Trypsin ke enzyme ea protheine (protein) e bolokiloeng ke karolo ea "pancreas" ea "pancreas". Qalong, ea etelletsoeng pele a le maemong a sa sebetseng, e leng trypsinogen, oa hlahisoa.
E kena duodenum 12, 'me ke moo e buoang ka lebaka la ketso ea enzyme e' ngoe ho eona - enterokinase.
Karolo ea lik'hemik'hale ea trypsin e thathamisitsoe e le protheine. Ka ts'ebetso, e fumanoa ho tsoa likhomo.
Mosebetsi oa bohlokoa ka ho fetisisa oa trypsin ke proteinolysis, i.e. ho petsoha ha liprotheine le li-polypeptides ka likarolo tse nyane - amino acid. Ke enzyme e thusang.
Ka mantsoe a mang, trypsin e senya liprotheine. Li-enzymes tse ling tsa pancreatic le tsona lia tsebahala - lipase, e kenyelletsoang ho cheng hoa mafura, le alpha-amylase, e arolang lik'habohaedreite. Amylase ha se enzyme ea pancreatic feela, e boetse e entsoe ka har'a litšoelesa tse qhekellang, empa ka bongata bo fokolang.
Trypsin, amylase le lipase ke lintho tsa bohlokoa ka ho fetesisa tšilo ea lijo. Ha ho na le bonyane e le 'ngoe ea bona, tšilo ea lijo e senyehile haholo.
Ntle le ho nka karolo ho etseng lijo tsa 'mele, "enypme" ea trypsin e sebetsa hantle haholo ho phekoleng maloetse a fapaneng:
- e thusa ho fokotsa ho ruruha 'meleng;
- e potlakisa pholiso ea ho chesoa, maqeba a matla;
- ho khona ho arola lisele tse shoeleng e le hore lihlahisoa tsa necrosis li se ke tsa kena maling le ho baka tahi;
- e etsa li-secretions tse tšesaane, li-secretions tse eketsehileng metsi;
- e nolofalletsa liquefaction ea likhahla tsa mali;
- e thusa ho phekola maloetse ka ho ruruha ha fibrinous;
- e ntlafatsa ho tlosoa ha masapo a puruse;
- e tšoara liphoso tse tebileng tsa ho ruruha ha molomo;
Boemong bo sa sebetseng, komporo ena e sireletsehile ka botlalo.
Kaha trypsin e na le thepa e joalo ea pholiso, e sebelisetsoa ho etsa meriana.
Joalo ka ntho leha e le efe e 'ngoe e sebetsang ea lithethefatsi leha e le life, tšebeliso ea trypsin e na le matšoao le litlolo tsa tšebeliso ea eona.
Ha o sebelisa lithethefatsi tse kenyeletsang trypsin, litlhahiso le litaelo tsa ngaka tsa ho sebelisa moriana li lokela ho nkuoa ka hloko.
Thupelo ea Trypsin:
- Amorphous - e ka sebelisoa feela ka lihlooho (sebakeng se fokolang sa letlalo).
- Crystalline - e tla ka sebopeho sa phofo e tšoeu-e mosehla, ka ho se be le monko o joalo. E sebelisoa ka kotloloho hape bakeng sa tsamaiso ea methapo.
Trypsin e fumaneha tlasa mabitso a fapaneng: "Pax-trypsin", "Terridekaza", "Ribonuclease", "Asperase", "Lizoamidase", "Dalcex", "Profezim", "Irukson". Litokisetso tsohle li lokela ho bolokoa sebakeng se omileng se lefifi ka mocheso o sa feteng likhato tse leshome.
Matšoao a sebelisoang ke:
- mafu a ho ruruha a matšoafo le airways (bronchitis, pneumonia, exudative pleurisy);
- lefu la bronchiectatic (ho ba teng ha li-extensions tse mpe ka har'a bronchi);
- ho chesoa ke tšoaetso le maqeba ka ho tsoa mokhoeng oa purulent;
- ho ruruha ho sa feleng ha tsebe (bohareng ba otitis media);
- ho ruruha hoa purifonia ea sebe se ka pele le se maxillary;
- lesapo la mokokotlo (osteomyelitis);
- lefu le sa foleng;
- ho petsoha ha kanale ea "lacrimal";
- ho ruruha hoa iris;
- liso tsa khatello;
- mathata a ka mor'a ho buuoa ka mahlo.
Khokahano ea tšebeliso ea trypsin ke:
- Karabelo ea mefuta eohle ea li-trypsin.
- Moea o eketsehileng oa matšoafo, kapa emphysema.
- Ho haella ha mosebetsi oa pelo.
- Liphetoho tsa Dystrophic le ho ruruha ka har'a sebete.
- Lefuba
- Lefu la fig.
- Pancreatitis ea sebetsa.
- Tlolo ea kahare ho sistimi ea ho ferekanya le anticoagulation.
- Lits'ebetso tsa ho ruruha ho liphio (jade).
- Hemorrhagic diathesis.
Litlamorao e ka ba life ka mor'a ho sebelisa trypsin?
- allergy
- pelo lippitations;
- redness le bohloko ka mor'a ho kenella ka har'a methapo ea methapo;
- hyperthermia
Ntle le moo, ho kuta ho ka 'na ha hlaha lentsoeng la mokuli.
Ha e sebelisoa ka holimo bakeng sa kalafo ea maqeba a omileng kapa maqeba a nang le lisele tse shoeleng, ho sebelisoa li-compress tsa trypsin tse kentsoeng.
Ho etsa sena, o hloka ho qhala 50 mg ea boitokisetso ba enzyme ka 50 mg ea saline ea mmele (sodium chloride, kapa saline ea 0.9%).
Ka tloaelo sebelisa lipompo tse tharo tse nang le mekhahlelo e meraro.
Kamora ho sebelisa compress, e kenngoa ka bandage mme e siuoe lihora tse mashome a mabeli a metso e mene.
Tsamaiso ea methapo 5 mg ea trypsin e hlapolotsoe ka 1-2 ml ea saline, lidocaine kapa novocaine. Ho batho ba baholo, liente li etsoa habeli ka letsatsi, bakeng sa bana - hang feela.
Tšebeliso ea mahareng. Kamora ho hlahisoa ha moriana, o ka se be maemong a tšoanang nako e telele, hobane sena se etsa hore ho be thata ho hlakola lekunutu. Hangata, kamora matsatsi a mabeli, sephiri sena se tsoa ka hara draina.
Kopo ea ho inhalation. Li-inhalations tsa Trypsin li etsoa ho sebelisoa inhaler kapa bronchoscope. Kamora ts'ebetso, ho molemo ho hlatsoa nko kapa molomo oa hau ka metsi a futhumetseng (ho latela hore na ts'ebetso e ile ea etsoa joang).
Ka sebopeho sa marotholi a mahlo. Li hloka ho huleloa lihora tse ling le tse ling tse 6-8 ka matsatsi a 3.
Likarolo tsa tšebeliso ea trypsin:
- Trypsin e thibetsoe ho etsa kopo ka maqeba a tsoang mali.
- E ke ke ea sebelisoa ho phekola mofetše, haholo-holo ka ulceration ea lisele.
- Ha e tsamaisoe ka matla.
- Ha ho phekoloa bana ba banyenyane, ho rala merero e le 'ngoe.
- Basali baimana kapa ba anyesang ba lokela ho sebelisa meriana ena ha feela kotsi ea lefu la hae kapa lefu la fetal e bohlokoa haholo.
Pharmacokinetics, ke. phetisetso ea lithethefatsi 'meleng ha e so ithutoe. Ho tsejoa feela hore ha ntja e kena 'meleng, trypsin e tlama alpha macroglobulins le alpha-1 antitrypsin (inhibitor ea eona).
Hajoale, ho na le lipalo tse ngata tse ntle mabapi le lithethefatsi tse nang le trypsin. Haholo-holo e fapaneng haholo ea ts'ebeliso ea eona ho ophthalmology. Ka eona, ho ruruha ha methapo ea methapo, methapo, ho ruruha le methapo ea methapo ea iris e ea alafshoa, hobane li-pathologies tsena ha ho se na phekolo e lekaneng li ka lebisa bofofu bo ke keng ba fetoha. Motsoako oa kalafo ea litokisetso tsa enzyme o nang le lithethefatsi tsa khale, lithibela-mafu, lihormone, meriana ea glaucoma e sebetsa haholo, e leng se eketsang sekhahla sa ntlafatso ea tishu.
Trypsin e thusitse ho fokotsa mafu a kopaneng, a kang ramatiki, polyarthritis, arthrosis le lefu la ramatiki. E fokotsa bohloko, e hatella ho ruruha, e khutlisetsa mekhahlelo e felletseng.
Ka likotsi tse tebileng, ho khaola ho tebileng, ho chesa, enzyme e lumella, bonyane, ho fokotsa boiketlo ba kakaretso ea motho ea hlasetsoeng, le ho potlakisa pholiso.
Theko e tloaelehileng ea litokisetso tsa trypsin ho la Russia e tsoa ho li-ruble tse 500.
Meleng, "trypsin" e bitsoang "immunoreactive" e ikemiselitsoe hammoho le ntho e hatellang tšebetso ea eona - alpha-1-antitrypsin. Sekhahla sa trypsin ke 1-4 μmol / ml.min. Keketseho ea eona e ka bonoa ha ho ruruha ho hoholo hoa manyeme, ts'ebetso ea oncological ho eona, ka cystic fibrosis, ho hloleha ho sa foleng ha liphio, hape ho ka tsamaisana le mafu a vaerase. Ho fokotseha hoa palo ea enzyme ho ka supa mofuta oa 1 lefu la tsoekere, kapa mafu a kaholimo, empa ka mefuta e sa foleng le maemong a morao.
Ntle le tlhahlobo ea mali, hangata bakuli ba fuoe kopi. Pele ho thuto ena, ha ho khothalletsoe lithibela-mafu tse 3 bakeng sa matsatsi a 3. Ha deciphering trypsin e mantle e ka se fumanoe. Hangata hona ke sesupo sa mekhoa ea "cystic fibrous" makhophong. Ho fokotseha ho hoholo ho eona ho bonoa ka cystic fibrosis, empa sena ha se bolele hore tlhahlobo ea bongaka e tiisitsoe, 'me ho hlokahala lithuto tse eketsehileng ho hlakisa. Hajoale, ho lumeloa hore boikemisetso ba ts'ebetso ea trypsin ka har'a makhopho ha a bonts'e letho.
Tlhahisoleseling e khuts'oane ka trypsin le li-enzyme tse ling li fanoa video videong ena.
