Molemong oa kalafo ea mofuta oa lefu la tsoekere la mofuta oa 2, ho sebelisoa li-hypoglycemic agents tse khethehileng kapa insulin. Moemeli ea nepahetseng oa hypoglycemic o nkuoa e le lefu la tsoekere.
Moriana o sebetsa haholo ebile o theko e tlase. Litsenyehelo tsa lithethefatsi Diabeteson 60 mg ke li-ruble tse 250-300. Moriana oa ngaka o sebelisoa.
Litšoantšiso tsa lefu la tsoekere ke eng? Phekolong ea mofuta oa lefu la tsoekere la mofuta oa 2, ho ka sebelisoa li-hypoglycemic, tse kenyelletsang lintho tse kang glimepiride, glibenclamide kapa glycvidone.
Ka bokhutšoanyane ka lefu la tsoekere le molao-motheo oa ts'ebetso
Lefu la tsoekere ke pheko ea lefu la tsoekere, leo karolo ea lona e sebetsang e leng gliclazide. Ke kopa ho tseba hore sehlahisoa se fumaneha ka tekanyetso ea 60 mg le 30 mg. Ntle le gliclazide, motsoako oa moriana o kenyelletsa lactose, hypromellose, magnesium stearate, maltodextrin, silicon dioxide.
Joale, phello ea hypoglycemic ea lithethefatsi e thehiloe ho eng? Gliclazide e fokotsa tsoekere ea mali ka ho tsosa secretion ea insulin ka lisele tsa beta tsa li-isanc tsa pancreatic tsa Langerhans. Ho diabetics, ka ts'ebeliso ea Diabeton, tlhoro ea pele ea "insulin secretion" e ea khutlisoa, mme monyetla oa ho tsoela pele ha thrombosis o fokotsehile.
Matšoao a ts'ebeliso ea lefu la tsoekere ke maemong a mang ha phekolo ea lijo e sa tsitsise maemo a tsoekere. Hape, moriana o sebelisoa ha ho na le menyetla ea ho ba le mathata a lefu la tsoekere la 2, haholoholo lefu la kelello.
Litaelo tsa tšebeliso li bolela hore lefu la tsoekere la 60 mg kapa 30 mg le lokela ho nooa le lijo. Ho feta moo, khafetsa tšebeliso ea matlapa ke 1 nako ka letsatsi. Tekanyetso ea ho qala ea letsatsi le letsatsi ke 30-120 mg. Ha u e khetha, lilemo, litšobotsi tsa motho ka mong le mokuli oa mali li nahaneloa.
Har'a lintho tse hanyetsanang ts'ebeliso ea lefu la tsoekere ke:
- Type 1 lefu la tsoekere.
- Nako ea lebone.
- Ntate-moholo oa lefu la tsoekere kapa komisi.
- Lefu la tsoekere la ketoacidosis.
- Hypersensitivity ho likarolo tsa moriana.
- Ho hloleha ha hepatatic kapa renal.
- Tšebeliso ea li-quinolones kapa miconazole.
Har'a litla-morao tsa lithethefatsi, litlolo tsa tšebetso ea tšilo ea lijo, ho se sebetse hantle ha letlalo le lisele tse ka tlasana li ka khetholoha. Hape, menyetla ea ho ba le mathata a hematological, ho kenyeletsa phokolo ea mali, leukopenia, granulocytopenia, e ke ke ea hlakoloa. Ka lebaka la liphetoho maemong a tsoekere ea mali, ho ka ba le ho ferekana ha litho tsa pono.
Litla-morao hangata li it rarolla hang hang ka mor'a ho tlohela moriana.
Glimepiride
Li-analogue tse ntle tsa lefu la tsoekere ke lithethefatsi tse kenyeletsang glimepiride. Ha e le analogue ea Diabeteson MV 30, o ka sebelisa Glimepiride 2 mg n 10. Theko ea lithethefatsi ke li-ruble tse 150-200. Ka tsela, Glimepiride 1 mg, 3 mg, 4 mg ea rekisoa. Tsena kaofela li fapana ka tekanyetso ea ntho e sebetsang letlapeng.
Setlhare sena ke sulfonylurea. Karolo e sebetsang ea lithethefatsi e sebetsa ka ho susumetsa ho tsoa ha insulin liseleng tsa pancreatic beta.
Glimepiride e ka sebelisoa kalafo ea mofuta oa tsoekere ea lefu la tsoekere la mofuta oa 2, haeba boemo ba tsoekere maling bo ke ke ba khalemeloa feela ka phekolo ea ho ja le ho ikoetlisa.
U ka nka joang analogue ea Diabeteson MV? Litaelo tsa tšebeliso li re moriana o lokela ho khethoa ke ngaka e tlang. Maemong ana, ngaka e lokela ho nahanela boemo ba tsoekere maling le morong.
E le molao, litekanyetso tsa pele tsa glimepiride ke 1 mg. Haeba tekanyetso e nyane ha e thusa ho tsitsisa boemo ba tsoekere maling, joale litekanyetso tsa letsatsi le letsatsi li nyolohela ho 2, 3 kapa 4 mg, ka ho latellana. Empa re lokela ho hopola hore tekanyetso e nyoloha butle butle ka nako ea libeke tse 1-2. Tekanyo e phahameng ea letsatsi le letsatsi ea lithethefatsi ke 6 mg.
Ehlile, Glimepiride, joalo ka moemeli leha e le ofe oa hypoglycemic, o na le lintlha tse 'maloa tsa contraindication hore li sebelisoe. Har'a tsona ke:
- Lefu la tsoekere le itšetlehileng ka insulin (mofuta oa 1).
- Lefu la tsoekere la ketoacidosis.
- Ntate-moholo oa lefu la tsoekere kapa komisi.
- Ho senyeha ho matla hoa ts'ebetso ho sebete.
- Ts'ebetso e sebetse hantle malebana le liphio, haholo-holo ho sebetsoa ke liphoko.
- Allergy ho likarolo tsa moriana. Ho feta moo, u ke ke ua nka glimepiride le haeba motho a e-na le mamello ho tse ling tse tsoang ho sulfonylurea.
Nakong ea kalafo, o tlameha ho latela lijo ka tieo. Empa re tlameha ho hopola hore, ha ho na monyetla o ka fokotsang ka matla tekanyo ea khalori. Ntle ho moo, ho ka hlaha mokokotlo oa hypoglycemic. Hape, nakong ea kalafo ho thibetsoe ka thata ho sebelisa joala leha e le bofe.
Litlamorao tsa glimepiride:
- Mathata a amanang le mosebetsi oa pelo le hematopoietic system. Li hlaha ka mokhoa oa ho theola khatello ea mali, thrombocytopenia, granulocytopenia, leukopenia, agranulocytosis, pancytopenia, erythropenia, anemia.
- Ts'ebetso ea ts'ebetso ea methapo ea kutlo le litho tsa kutlo - ho tsekela, migraine, ho fokotseha ho fokotsehang ha pono ea mahlo.
- Ho nyekeloa ke pelo, ho hlatsa, bohloko ba ka mpeng, ho utloa bohloko bo boholo sebakeng sa epigastric, lets'ollo, cholera ea methapo ea methapo.
- Hypoglycemic coma.
- Hyponatremia.
- Litla-morao.
- Ho hema hanyane.
- Hepatitis, mosebetsi o eketsehileng oa hepatic transaminases.
- Linepe.
Ha litla-morao tse matla li hlaha, sethethefatsi sea hlakoloa, 'me ho khethoa moemeli e mong oa hypoglycemic.
Glibenclamide ea lefu la tsoekere
Haeba Diabeteson MV 30 ha e loketse, o ka reka sesebelisoa se kang Glibenclamide. Moriana o ratoa haholo ke batho ba lefu la tsoekere, ka lebaka la ho sebetsa ha lona haholo le mamello e ntle. Theko ea Glibenclamide 5 mg n 100 ke li-ruble tse 100-120 feela.
Sebakeng sena sa Diabeteson ho na le ntho e sebetsang ea glibenclamide, le lintho tse thusang - lactose monohydrate, starch ea litapole, povidone, E124, magnesium stearate.
Glibenclamide e susumetsa lisele tsa pancreatic beta, e tsamaeang le ts'usumetso le keketseho e eketsehang ea "insulin" ea "insulin". Setlhare se sebetsa hantle boteng ba makhopho a maseli a sebetsang a beta a hlahisang insulin ea nako e telele. Ntho e sebetsang ea Glibenclamide e thusa ho fokotsa bongata ba liplatelete.
Moetsi o bontša ka litaelo hore moriana ona o lokela ho sebelisoa kalafong ea lefu la tsoekere la mofuta oa 2 ha phekolo ea lijo le mehato e meng ea kalafo e sa thusa ho fetisa litekanyetso tsa tsoekere ea mali.
Motsoako oa pele oa glibenclamide ke 2,5-5 mg. Maemong ana, mokuli o hloka ho lula a lekola boemo ba glycemia. Haeba bonyane litekanyetso li-athari tsa hypoglycemic ha li hlahisoe, joale lethal dose ea letsatsi le letsatsi ea tsosoa.
Haeba ho hlokahala, glibenclamide e kopantsoe le li-agents tse ling tsa hypoglycemic. Maemong ana, hangata litekanyetso li fokotsoa 'me li khethoe ka tsela e tla fokotsa kotsi ea ho ba le komello ea hypoglycemic.
Lits'ebetso mabapi le tšebeliso ea moriana:
- Allergy ho likarolo tsa moriana. Ha e sa kgothaletswa ho nka matlapa a batho ba lefu la tsoekere ba neng ba bile le karabelo ea hypersensitivity ho tse ling tse tsoang ho sulfonylurea.
- Type 1 lefu la tsoekere.
- Ntate-moholo oa lefu la tsoekere kapa komisi.
- Ho hloleha kahare ho sebete.
- Ho hloleha ha tsebe le mathata a mang a tšebetso a liphio.
- Nako ea bokhachane le pelehi.
- Ho bolaoa ke lefu la tsoekere ka lebaka la ho buuoa.
Ho bohlokoa ho hopola hore phello ea hypoglycemic ea Glibenclamide e matlafatsoa haeba motho a sebelisa sulfonamides, painkillers, coumarin derivatives, heparin. Thepa e theolang tsoekere e boetse e ntlafatsoa haholo ha e kopantsoe le li-inhibitors tsa MAO, li-hypocholesterolemic agents, lithibela-mafu tse ling le li-barbiturate.
Empa ho fokotseha ha thepa ea hypoglycemic ho ka hlaha haeba Glibenclamide e kopantsoe le lithibela-mafu tsa sehlopha sa rifamycin kapa thiazide diuretics.
Litlamorao tsa meriana:
- Hypoglycemia
- Mathata a amanang le mala. Ho bonahatsoa ka mokhoa oa ho hloka takatso ea lijo, ponahalo ea tatso ea tšepe e ka hanong, ho hlatsa, lets'ollo, bohloko ba ka mpeng, ho otla ha pelo.
- Litla-morao.
- Cholestasis.
- Ts'ebetso ea sebete e sa sebetseng.
- Mathata a tsamaiso ea hematopoietic.
- Tloloko ea kutloelo-bohloko.
Hape, thuto ea ts'ebeliso e re glibenclamide e ka baka nts'etsopele ea photosensitivity.
Glurenorm joalo ka sebaka
Lefu la tsoekere le ka nkeloa sebaka ke sesebelisoa se kang Glyrenorm. Moemeli enoa oa hypoglycemic ha a na katleho. Theko ea Glurenorm 30 mg n 60 ke li-ruble tse ka bang 500-620.
Karolo e sebetsang ea lithethefatsi ke glycidone. Bakeng sa merero e thusang, lactose, starch ea poone, stearate ea magnesium e eketsoa matlapeng. Motheo oa ts'ebetso ea ts'ebetso ea Glurenorm e thehiloe holim'a eng?
Glycvidone (ntho e sebetsang) e phahamisa sephiri sa insulin ea endo native ke lisele tsa beta tsa manyeme. Ka mantsoe a mang, moeli oa ts'ebetso ea moriana o ts'oana le li-agents tse ngata tsa hypoglycemic.
Ka thuso ea Glyurenorm, ho ka khonahala ho phekola lefu la tsoekere la mofuta oa 2, ha lijo le ho ikoetlisa li sa thusa ho tsitsisa boemo ba tsoekere maling. Ka linako tse ling moriana ona o sebelisoa hammoho le lithethefatsi tse ling tsa hypoglycemic.
U ka sebelisa lipilisi joang? Litaelo tsa tšebeliso li bolela hore lethalinyana la pele ha lea lokela ho feta 15 mg. Ho hlokahala hore u noe pilisi ka lijo. Ka ho se sebetse hantle ha mehato ea kalafo, litekanyetso li eketseha butle-butle. Empa re lokela ho hopola hore lethal dose e phahameng ea letsatsi le letsatsi ke 120 mg. Ho thata ho tšela monyako ona.
Contraindication bakeng sa ts'ebeliso:
- Mofuta oa 1 oa lefu la tsoekere.
- Precomatose kapa komisi.
- Lefu la tsoekere le rarahaneng ke acidosis kapa ketosis.
- Sesebelisoa sa makhopho.
- Nako pele ho buuoa.
- Mathata a teng ka har'a sebete.
- Hepatic porphyria.
- Allergy ho likarolo tsa moriana.
Har'a litla-morao tsa Glenrenorm, agranulocytosis, leukopenia, thrombocytopenia, hypoglycemia e ka khetholloa. Hape, motho a ke ke a qhelela ka thōko monyetla oa ho otsela, ho ba le letsoele, migraine, paresthesia, mathata a bolulo, karabelo ea mefuta-futa.
Ho boetse ho tlalehiloe hore ho nka Glurenorm ho ka baka angina pectoris, ho nyekeloa ke pelo le khatello e tlase ea mali. Qalong ea kalafo ea kalafo, ho ferekana ha ts'ebetso ea tšilo ea lijo ho ka khoneha, ho bonahatsoa ka mokhoa oa ho hlatsa, ho sokela, molomo o omileng. Video e sehloohong sena e tla bua ka Diabetes.
