Sesebelisoa sena sa metabolic se ntlafatsa metabolism 'meleng. Thioctic acid e khothalletsa ho felisoa ha li-radicals tsa mahala. Ka thepa ea eona ea biochemical, acid e haufi le livithamini tsa B.
Lebitso la Machaba le sa Tšoanelehang
Lefats'eng ka bophara, moriana o fumaneha tlasa lebitso la Thioctic Acid kapa Thioctacid.
Thioctic acid e khothalletsa ho felisoa ha li-radicals tsa mahala.
ATX
Khoutu ea tafole ea ATX ke A16AX01.
Sebopeho
Ho pakete e le 'ngoe ea sele ke likotoana tse 10, 20 kapa 30. Lithutso li fumaneha ka lebokoseng la karete. Letlapa le leng le le leng le na le 600 mg ea α-lipoic acid. Lithako tse thusang:
- cellcose ea microcrystalline;
- crodarmellose sodium;
- silika;
- lactose monohydrate;
- magnesium stearate.
Toundctic acid e pota-potileng ka mahlakoreng a mabeli a letlapa, e koahetsoe ka 'mala o mosehla o bopiloeng ka:
- hyproloses;
- hypromellose;
- macrogol;
- tekanyetso ea titanium;
- Dae e khethehileng ea quinolative.
Ketso ea pharmacological
Sesebelisoa se na le ts'ebetso ea ho fokotsa lipid, e bapala karolo ea metabolite e sebetsang. Setlhare se tlama hammoho li-radicals tsa mahala, se ntlafatsa trophism ea methapo, se eketsa boemo ba glycogen bokong, se ntlafatsa ts'ebetso ea eona, se theola insulin.
Thioctic acid e ameha ho metabolism ea lipid le carbohydrate. O kenya letsoho ts'ebetsong e nang le chefo e joalo ka decarboxylation ea pyruvic acid.
Ntho ena e sebetsa e le coenzyme maemong a mangata aenzenzyme e hlahang mitochondria ea lisele.
Mofumahali
Ntho ena e kenella ka potlako mme e kenella hantle ke mmele. Kamora hora ea 1, motsoako oa asiti 'meleng o fihla boleng ba eona bo phahameng. Bioavailability e fihlella 30%.
Taba ea pele, asiti e kena ka har'a sebete. Ntho e entsoe ka setho sena.
Taba ea pele, asiti e kena ka har'a sebete. Ntho e entsoe ka setho sena. Mona ketane ea lehlakore ea thioctacide e na le oxidized ebile e kopantsoe. Ho etsa lintho hantle ho hlaha ka liphio.
Matlapa a thioctic acid tse 600 ke afe?
Sesebelisoa se sebelisoa kalafong ea:
- sensory-motor kapa peripheral polyneuropathy e hlahisoang ke lefu la tsoekere;
- lekhoba la joala;
- polyneuropathy;
- liphetoho tsa pelo;
- hepatitis;
- cirrhosis ea sebete;
- ho fokola ha mafura;
- coronary atherosclerosis;
- botenya
- Hyperlipidemia
Setlhare se u lumella ho fokotsa cholesterol, ho netefatsa metabolism e tloaelehileng ea mafura.
Contraindication
Phapang e ka sehloohong ke hypersensitivity ea motho ho thioctic acid. Ha hoa lumelloa ho sebelisa lithethefatsi maemong a latelang:
- nakong ea bokhachane le pelehi;
- ho bana ba ka tlase ho lilemo tse 18;
- le khaello ea lactase, allergies ho lactose, tsoekere-galactose malabsorption.
U ka nka lipilisi tsa thioctic acid tse 600 joang?
Nakong ea tsamaiso, matlapa ha a hatelloe, empa a entsoe ka botlalo. Li nooa halofo ea hora pele ho lijo tsa hoseng 'me li hlatsuoa ka metsi. Motsoako oa letsatsi le letsatsi o khothalletsoang bakeng sa kalafo ea polyneuropathies ke letheba le le leng. Nako e telele ea thupelo ke libeke tse 12. Ke ngaka feela e eang teng e ka lelefatsang kalafo.
Ka ho haha 'mele
Lipapaling tsa ho haha 'mele le tse ling tsa lipapali tse matla, ho nkuoa thioctic acid ho fokotsa litlamorao tsa khatello ea maikutlo le ho hlaphoheloa boikoetlisong bo matla ba' mele. Acid hape e u lumella ho tlosa mafura a 'mele. Baatlelete ba ka nka tlatsetso makhetlo a 3 ka letsatsi, boleng ba tekanyetso e le 'ngoe boemong bona bo ka fihla 50 mg. Ka mojaro o boima, litekanyetso tsa letsatsi le letsatsi li nyolohela ho 600 mg.
Lipapaling tsa ho haha 'mele le tse ling tsa lipapali tse matla, ho nkuoa thioctic acid ho fokotsa litlamorao tsa khatello ea maikutlo le ho hlaphoheloa boikoetlisong bo matla ba' mele.
Le lefu la tsoekere
Litsebi tsa lefu la tsoekere li ka fetohela matlapeng kamora ts'ebetso ea ts'ebetso ea methapo e kenelletseng. Nakong ea thupelo e le 'ngoe, ho sebelisoa li-ampoules tse 15. Nakong e tlang, bakuli ba nang le lefu la tsoekere ba lumelloa ho nka Letlapa le le 1 la thioctacid ka letsatsi pele ho lijo tsa hoseng.
Litla-morao tsa thioctic acid matlapa a 600
Ha u ntse u sebelisa lithethefatsi, tsoekere ea glucose e ka theoha. Ho na le matšoao a mang:
- ho hlohlona le ho senyeha ha mokhoa oa ka mpeng ka mokhoa oa ho nyekeloa ke pelo, ho hlatsa, ho opeloa ke pelo, lets'ollo, colic ka mpeng;
- ho ts'oaroa ke lintho tse sa utloahaleng - makhopho, bofubelu ba letlalo, ho teneha, urticaria, ka linako tse ling ho thothomela ha anaphylactic;
- phetoho ea tatso;
- hypoglycemia le mofufutso o feteletseng, hlooho ea hlooho le ho tsekela, ho senyeha ha pono.
Ho se sebetse hantle ka polasetiki ho bonoa feela ka tsamaiso ea methapo ea lithethefatsi.
Litaelo tse khethehileng
Mosebetsi ho bana
Bana ba ka tlase ho lilemo tse 18 ha baa lumelloa ho sebelisa lithethefatsi.
Sebelisa nakong ea bokhachane le pelehi
Kaha phello ea sethethefatsi le phello ea eona kholisong ea lesea ha e e-so thelisoe, ha ea lumelloa ho e nka nakong ea kemaro le ho lactation.
Tekanyo ea joala
Ethanol e fokotsa ts'ebetso ea lithethefatsi, lino tse tahang le thioctacid ha li lumellane.
Tšusumetso ho bokhoni ba taolo ea methapo
Ka tlhokomeliso, o lokela ho nka moriana nakong ea mosebetsi o hlokang tlhokomelo e eketsehileng. Maemong ana, ho sebelisa lithethefatsi ho ka ba kotsi.
Bongata
Matšoao a mantlha a bokhoba ba bongoana:
- ho nyekeloa ke pelo, ho hlatsa
- hlooho e bohloko
- ho ts'oaroa ka mokhoa o susumetsang;
- liphetoho mabapi le tekanyetso ea acid-base, e bonahatsoang ka mokhoa oa lactic acidosis;
- mathata a ho tsoa mali, ao ka linako tse ling a behang bophelo kotsing;
- skeletal mesifa necrosis;
- hemolysis;
- ho hloleha hoa litho tse ngata.
Maemong a mang, mokuli ka mor'a ho sebelisa tekanyetso e phahameng ea lithethefatsi o oela ka har'a komello ea hypoglycemic. Setlhare ha se na antidote, haeba ho na le chefo, kalafo ea matšoao e etsoa, ka linako tse ling ka ho kena sepetlele.
Ho sebelisana le lithethefatsi tse ling
Thioctacid e ntlafatsa ts'ebetso ea lithethefatsi tsa antidiabetes, insulin le lithethefatsi tse ling tse fokotsang tsoekere ea mali mme li sebelisoa kalafong ea lefu la tsoekere la mofuta oa 1. Litsebi tsa lefu la tsoekere li lokela ho lekola maemo a tsoekere, ho fokotsa meriana ha ho hlokahala.
Nakong ea kalafo le thioctacid, katleho ea cisplatin e fokotsehile haholo. E theha khokahano ea tšepe le e 'ngoe, empa ha e khothalletsoe ho e nka ka nako e le ngoe le litokisetso tsa tšepe le magnesium. Ntho ena e ntlafatsa matla a khahlanong le ho ruruha a ho nka li-glucocorticosteroids. U ke ke ua e sebelisa hammoho le infusions tse nang le fructose.
Li-analog
Ho sebelisoa phofo e bosehla ea 'mala o mosehla bakeng sa ho lokisa li-infusions le tharollo ea metsi bakeng sa ente. Analog ea matlapa ke tharollo bakeng sa tsamaiso ea methapo, e hlahisoang ka ampoules. Lithethefatsi tse ling tse nang le thepa e tšoanang:
- Alpha lipoic acid.
- Lipothioxone.
- Borokho.
- Neuroleipone.
- Tiogamma.
- Tiolepta.
- Espa Lipon.
- Oktolipen.
Lipehelo tsa khefu ea khemisi
A na nka reka ntle le lengolo la ngaka?
Setlhare se fanoa feela ka taelo ea ngaka.
Theko
Litsenyehelo tse tloaelehileng tsa lithethefatsi matlapeng ke li-ruble tse 1,500.
Maemo a polokelo ea moriana
Moriana o lokela ho bolokoa hole le khanya ea letsatsi, sebakeng se ommeng le se futhumetseng se sa fumaneheng ho bana. Mocheso oa moea ha oa lokela ho feta 25 ° С.
Letsatsi la ho felloa ke nako
Setlhare sena se bolokiloe lilemo tse 3.
Moqapi
Setlhare sena se etsoa ke k'hamphani ea Jeremane AWD.pharma.
Moriana o lokela ho bolokoa hole le khanya ea letsatsi, sebakeng se ommeng le se futhumetseng se sa fumaneheng ho bana.
Litlhahlobo
Lingaka
Elena Sergeevna, ngaka e akaretsang, Minsk
Sesebelisoa se thusa hantle bakuli ba nang le lefu la tsoekere. Thioctic acid e bontšitsoe e sebetsa hantle ho phekoleng lefu lena.
Irina Olegovna, setsebi sa endocrinologist, Nizhny Novgorod
Ngaka e 'ngoe le e' ngoe e fang bakuli ba eona lithethefatsi e tlameha ho ba le bonnete ba hore e na le tšireletseho. Ts'ebetsong ea ka, ke bone khafetsa hore thioctacid ea sebetsa.
Bakuli
Anna, ea lilemo li 50, Kazan
Ke na le lefu la tsoekere, hape ho na le mathata le lesapo la mokokotlo. Ke nkile moriana ona likhoeli tse tharo. Ha kea ka ka hlokomela matšoao a lehlakoreng le leng, ntle le sena, boima bo ile ba fokotseha.
Olga, ea lilemo li 25, Kostroma
Litaelo li re ha o ntse o sebelisa moriana o ka baka ho kulisoa. Re ne re sa mamellane ka lithethefatsi, le ha ke le allergic.
