Ts'ebeliso ea li-inhibitors tsa liprotheine bakeng sa kalafo ea manyeme

Ka pancreatitis, ts'ebetso ea liprotheine e lebisa ho ruruheng ea setho le nts'etsopele ea libaka tsa necrotic.

Ho thibela ts'ebetso e joalo ea pathological, setsebi se khetha Contrical, Trasilol, Gordoks kapa Antagozan. Tšebeliso ea lithethefatsi tsena bakeng sa tsamaiso ea methapo e bohlokoa ka letsatsi la pele la pancreatitis e hlobaetsang.

Mefuta ea Enzymes ea Pancreatic

Mosebetsi o ka sehloohong oa manyeme ke ho etsa mesebetsi ea endocrine (ka hare) le exocrine (kantle). Ts'ebetso ea endocrine e na le tlhahiso ea lihormone - insulin, e theolang tsoekere le glucagon, e khothalletsang ho hlahisoa ha tsoekere maling.

Ts'ebetso ea exocrine ea manyeme ke ho hlahisa li-enzyme tse khethehileng (li-enzyme) tsa ho sefa lijo. Li lokela ho aroloa ka lihlopha tse 'maloa - li-enzymes tsa lipolytic, amylolytic le proteinolytic. A re ke re hlahlobeng ka botlalo leseli ka leng.

Li-enzyme tsa lipolytic. Sehlopha sena se ikarabella bakeng sa ho phatloha ha mafura ho mafura acid le glycerol. Prolipase ke enzyme e sa sebetseng ea lipase eo, ha e kena ka har'a duodenum, e kopana le colipase.

Ho qala ha lipase ho etsahala ka bongata ba letsoai la bile le trypsin. Ho phatloha ha likarolo tsa lipolytic ho etsoa ka lihora tse 7-14. Li-glomeruli tsa Renal li ikarabella bakeng sa ho filtara ha tsona: li khothalletsa ho monya ha lipase ka sebopeho sa lisele, ka hona likaroloana tsa likarolo tsa lipolytic ha li fumanoe ka moroto. Lintho tse tšoanang le lipase li boetse li hlahisoa ke sebete, matšoafo le mala.

Li-enzyme tsa Amylolytic. Ho na le mefuta e 'maloa - alpha, beta le gamma amylase. Sehlopha sena sa li-enzyme se boetse se bitsoa starch. Ts'ebetsong ea tšilo ea lijo, ke alpha-amylase feela e amehang.

E boetse e hlahisoa ka tekanyo e nyane ke litšoelesa tse nang le mongobo, haholo ha e hlafuna lijo. Ka hona, re utloa tatso e monate ha re ntse re hlafuna lijo tse nang le setlolo - raese kapa litapole tse khotliloeng. Ka lebaka la amylase, ts'ebetso ea ho ts'oaroa ha starch le lik'habohaedreite tse ling tse rarahaneng li fetoha bonolo.

Li-enzyme tsa Proteolytic. Mosebetsi oa mantlha oa sehlopha sena ke ho phatloha ha liprotheine. Li-enzymes tsa Proteolytic li kenya letsoho ho fokotseha ha li-amino acid tse tlamang tse fumanehang ka har'a peptides le liprotheine. Ho na le mefuta e 'meli e fapaneng ea protheine ho lero la pancreatic:

1. Peptidase, kapa exopeptidase, e ikarabellang bakeng sa hydrolysis ea metsoako ea kantle ea li-peptide.
2. Proteinase, kapa endopeptidase, e felisang metsoako e ka hare ea li-peptide.

Ka hona, lipase, amylase le proteinase li etsa lero la pancreatic, leo ha le kena ka duodenum, le qhekellang limolek'hule tse thata ho etsa metsoako e bonolo.

Lisosa le matšoao a pancreatitis

Ho motho ea phetseng hantle, ts'ebetso ea li-enzymes tsa pancreatic e etsahala ka duodenum.

Haeba ts'ebetso ea amylase, proteinase le lipase e qala ho manyeme ka boeona, re ka bua ka ho hloleha ha setho.

Pancreatitis e utloisisoa e le motsoako oa syndromes le maloetse a tsamaeang le ts'ebetso ea li-enzymes ka har'a gland, e lebisang ts'ebetsong ea "ho ikenya". Ka lebaka leo, ha ba kene ka har'a duodenum, mme tšilo ea lijo e a khathatseha.

Ho na le mabaka a 'maloa a lebisang ts'ebetsong e joalo ea pathological:

• khafetsa ho noa
• ho sitoa ho latela lijo tse nang le phepo e nepahetseng;
• tšebeliso e feteletseng ea lijo tse halikiloeng le tse mafura;
• ho ja lijo tse matlafatsang ka mor'a ho ja ka thata kapa ho itima lijo ka thata;
• ho ja ka mokhoa o sa laoleheng oa meriana e itseng;
• tsamaiso ea tšilo ea lijo;
• pathology ea tlhaho e tšoaetsanoang.

Ka ts'ebetso ea li-enzymes ka har'a manyeme, ho ruruha ho etsahala: e eketseha ka boholo, 'me libaka tsa necrotic li hlaha. Ts'ebetso e joalo e ke ke ea ba sesoeu, ho feta moo, ho na le tlolo ea mokhoa oa "gastrointestinal".

Ka khaello ea li-enzymes tsa pancreatic ka duodenum le ho ruruha ha manyeme, matšoao a latelang a bonoa:

1. Bohloko ho hypochondrium ea leqele, hangata ea mofuta oa shingles.
2. Phokotso ea bohlokoa ea bokooa, malaise le bofokoli ka kakaretso.
3. Dyspeptic disorder - ho thunya, ho nyekeloa kapa ho hlatsa, ho hloka takatso ea lijo, setofo se holofetseng.

Matšoao a lefu lena a ka fapana le ho haella ha enke e itseng:

• Khaello ea Amylase e lebisa ho letšollo, khaello ea livithamini, ho fokotsa boima ba 'mele. Metsoako e fetoha metsi, le likaroloana tse sa koaeloang tsa lijo li teng ka ho eona.
• Lenane le sa lekaneng la lipase le tlotsang mafura le baka steatorrhea - keketseho ea palo ea mafura setulong. Ka pancreatitis, metsamao ea "bowel" e fetoha mosehla kapa 'mala oa lamunu, motsoako oa mucus o bonoa ho bona.
• Ka bofokoli ba protheine, metsoako ea protheine e sa tsejoeng e fumaneha ka har'a maro. Letšoao le khethollang ke ho hola ha phokolo ea mali.

Haeba motho a hlokomela lipontšo tse joalo, o lokela ho batla thuso ea bongaka kapele kamoo ho ka khonehang. Ngaka e tla u fa lengolo la liteko le kalafo e lekaneng.

Natural Pancreatic Enzyme Inhibitors

Mmele ha o hlahise feela lintho tsa enzymatic tse tlatsetsang ho phatloheng ha limolek'hule tse rarahaneng, empa hape le li-inhibitors tsa secretion ea pancreatic, i.e. dikarolo tse thibelang tlhahiso e feteletseng ya lero la pancreatic.

Li-block tsa enzyme li kenyelletsa pancreatic polypeptide (PPP), YY peptide, somatostatin, glucagon ea pancreatic, pancreastatin le neuropeptides.

Lihlekehleke tsa Langerhans, tse fumanehang mohatleng oa manyeme, li hlahisa lihormone tse khethehileng, PPP, e thibelang tlhahiso ea metsi, li-enzyme le bicarbonate. E boetse e thibela tlhahiso ea acetylcholine.

Secretion ea PPP e eketseha maemong a joalo:

1. ka ho fepa ka kelello kapa ho ja lijo;
2. kamora ho hlohlelletsa methapo ea botšehali;
3. ka acidization ea duodenum;
4. ha e pepesetsoa gastrin le gastrin-e lokollang peptide;
5. ha ho pepesoa lekunutu, cholecystokinin le VIP.

The distal ileum le kolone e ntša YY peptide hang hoba mafura a kene ka har'a tšilo ea lijo. Peptide ena e thusa ho fokotsa ho tšoenyeha ha tšoelesa ka litlamorao tsa cholecystokinin le secretin.

Lisele tsa pancreatic D le membrane ea mucous ea tšilo ea lijo e hlahisa somatostatin. Hormone ena e thibela tlhahiso ea li-enzyme le bicarbonate. Sisteme ea methapo ea kutlo e nka karolo ho hlahiseng somatostatin, hang ha mafura le amino acid e tsoa lijong.

Li-inhibitors tse ling tsa pancreatic li emeloa ke lihormone tse joalo:

• Pancreatic glucagon, e emisang tlhahiso ea maro, li-bicarbonate le enzymes.
• Pancreatin, e thibelang ho lokolloa ha acetylcholine. E hlahisoa qetellong ea methapo ea botsana.
• Neuropeptides, e nang le calcitonin-information peptide (e susumetsa somatostatin) le enkephalins (fokotsa tlhahiso ea acetylcholine).

Ka lits'ebetso tse senyang gland, secretion ea pancreatic enzyme inhibitors e ka senyeha, ka hona, meriana e lokela ho nkuoa.

Melao-motheo ea kalafo bakeng sa pancreatitis

Likarolo tse peli tsa bohlokoa tsa kalafo e sebetsang bakeng sa lefu lena ke lijo le meriana. Mokhoa oa phekolo o ntlafatsoa ka bonngoe ho latela botebo ba lefu lena le tšenyo ea manyeme.

Lijo tse khethehileng tsa "pancreatitis" li thehiloe ho nomoro ea 5 ea lijo ho latela Pevzner. E felisa tšebeliso e feteletseng ea lijo tse nang le lik'habohaedreite le mafura hape e reretsoe ho ja lijo tsa protheine.

Ka ho qala ha pancreatitis e sa foleng, ho laetsoe matsatsi a 3-4 a ho itima lijo. Nakong ena, o tlameha ho hana ho ja le ho noa metsi a futhumetseng a letsoai haholo, mohlala, Borjomi.

Kamora ho bolaoa ke tlala le pancreatitis, lijo tse bolokiloeng li hlahisoa lijong tse ke keng tsa imetsa tsamaiso ea lijo. Bakuli ba nang le pancreatitis ba lumelloa ho sebelisa:

• mefuta ea lijo tsa nama le litlhapi;
• sopho ea meroho le moroho o hloiloeng;
• mahobe le li-biscuits tsa maobane;
• lihlahisoa tsa lebese la skim;
• litholoana tse ncha, litlama le meroho;
• lijo-thollo tse phehiloeng ka metsing kapa lebese la skim;
• mahe ka lipalo tse fokolang;
• rosehip moro, mahe a linotsi kapa jeme (e lekantsoe).

Ka ho ruruha ha manyeme, ho bohlokoa ho hana lijo tse eketsang tšilo ea lijo:

1. Lihlahisoa tsa chokolete, lijo-thollo, likuku.
2. Bohobe bo bocha.
3. Lijo tse halikiloeng.
4. Ho bolokoa, ho tsubelletse nama le li-pickles.
5. Lijo tse mafura le tlhapi.
6. Lihlahisoa tsa lebese tse mafura.
7. Lino tse khabisitsoeng ka khalase.
8. Linoko.
9. Mapheo a ruileng.
10. Ho na le mahe a mangata.
11. Tee e matla le kofi.
12. Sosebelisoa.
13. Li-legum le tamati.

Ka ho eketsoa ke pancreatitis e sa foleng, ho bohlokoa ho latela boroko ba ho robala.

Moriana bakeng sa makhopho a kenyelletsa ts'ebeliso ea:

• li-enzyme tsa enzyme ho fokotsa ts'ebetso ea liprotheine tsa "pancreatic" (proteinases);
• li-antibacterial agents ho qoba lits'ebetso tsa ho ruruha tsa mokokotlo oa mokokotlo, ho ruruha ha lera la bursa ea omental, nts'etsopele ea pancreatic necrosis le rotul cellulose ea sebaka se ka morao ho peritoneum;
• Li-blockers tsa H2 ho fokotsa tlhahiso ea hydrochloric acid;
• li-antacids tsa ho khelosa hydrochloric acid ka mpeng;
• antispasmodics bakeng sa tsitsipano ea mesifa e boreleli e amanang le ts'ebetso ea sphincter e sa sebetseng ka har'a duct ea pancreatic;
• lithethefatsi tsa anticholinergic ho thibela lits'ebetso tse sa tloaelehang ho ganglia le cortex ea "cerebral";

Ntle le moo, li-enzymatic agents li sebelisetsoa ho ntlafatsa ts'ebetso ea tšilo ea lijo le ho felisa ho senyeha ha dyspeptic.

Melemo e sebetsang

Ka letsatsi la pele la ho eketsa mofuta o sa foleng, ts'ebeliso ea liprotheine tsa thibelo ea pancreatitis e bohlokoa. Lithethefatsi tsena li tlosa sesosa sa ponahalo ea tsepamisang mohopolo le ho hasana ha libaka tsa necrotic.

Litlhare li fumaneha ho pulmonary parenchyma le manyeme a likhomo.

Ka tlase ho litlhare tse sebetsang hantle haholo, ke hore na moriana o noang ngaka e ikemiselitseng ka kotloloho. Ha li fumanehe ka mokhoa oa matlapa, empa ka sebopeho sa ho tsepamisa mohopolo kapa lyophilisate bakeng sa infusion.

Phekolo ea pancreatitis le inhibitors e nang le intravenous tsamaiso e etsoa feela maemong a supine. Ho feta moo, mooki le ngaka ba lokela ho hlokomela boemo ba mokuli ka hloko. Lijo No. 5 le tsona li tlameha ho bolokoa ka hloko, tseo, hammoho le phekolo ea lithethefatsi, tse tla netefatsa hore mokuli o fola ka katleho ntle le mathata.

Mokhoa oa ho phekola pancreatitis o tla hlalosoa ke litsebi videong ena.