Glidiab ke setlhare se batloang hohle seo ketso ea sona e etselitsoeng ho ntlafatsa maemo a bakuli ba nang le lefu la tsoekere la mofuta oa 2. Lintho tse sebetsang tsa sebopeho li thusa ho fokotsa bongata ba tsoekere le ho theha taolo ea glycemic.
Lebitso la Machaba le sa Tšoanelehang
INN Gliclazide (gliclazide).
Ka Selatine - Glidiab.
Ath
Boemong ba lihlopha tsa atomiki le tsa bongaka, moriana o fuoa khoutu ea A10BB09.
Glidiab ke setlhare se batloang hohle seo ketso ea sona e etselitsoeng ho ntlafatsa maemo a bakuli ba nang le lefu la tsoekere la mofuta oa 2.
Lokolla liforomo le sebopeho
Glidiab e fumaneha ka mokhoa oa matlapa a nang le sebopeho se pota-potiloeng le tranelate (kapa e 'mala o monyane). Sephutheloana sena se na le matlapa a 60.
Motsoako o ka sehloohong oa motsoako ke gliclazide. Bophahamo ba eona ka har'a letlapa le leng le le leng le fihla ho 80 mg.
Glidiab MV e na le 30 mg ea ntho e sebetsang.
Sebopeho se thusang sa likarolo se kenyeletsa: magnesium stearate, tsoekere ea lebese, talc, hypromellose, sodium starch glycolate, MCC.
Glidiab e fumaneha ka mokhoa oa matlapa a pota-potiloeng ka sebopeho.
Ketso ea pharmacological
Matlapa ke setlhare sa sehlopha sa lianstantike tsa maiketsetso. Matla a lithethefatsi a ikemiselitse ho lokisa lits'ebetso tse 'maloa tsa pathological:
- Lisele tsa pancreatic B li qala ho hlahisa insulin ka mafolofolo;
- li-tishu tsa pherekano li fumana kutloisiso e eketsehileng ea insulin;
- ketso ea tsoekere e fumana thepa e matlafalitsoeng ea insulin;
- nako ea ho qaleha ho ja ho fihlela e qala tlhahiso ea insulin e fokotsehile;
- keketseho ea postprandial ea maemo a tsoekere e fokotsehile;
- tlhoro ea pele ea tlhahiso ea insulin e ea khutlisoa.
Lithethefatsi li na le phello e ntle ho microcirculation:
- permeability ea vascular e khutlisetsoa;
- pokello ea liplatelete le khokahano li fokotsehile;
- physiological parietal fibrinolysis ke ntho e tloaelehileng;
- menyetla ea ho ba le atherosulinosis le microthrombosis e ea fokotsoa;
- e fokotseha kutloisiso ea li-receptor tsa vascular ho adrenaline.
Bohlokoa ba moriana ona ke hore o ama ka kotloloho mohato oa pele oa insulin secretion. Tšobotsi ena e e khetholla ho mekhoa e meng, hobane bakuli ha ba eketse boima ba 'mele. Ho latela lijo tse khothalletsoang ke ngaka, bakuli ba nang le boima ba 'mele haholo ba ka khutlisa boima bo tloaelehileng ba' mele.
Mofumahali
Kamora ho nka moriana, tekanyo e kholo ea karolo e sebetsang ea plasma ea mali e fihlella kamora lihora tse 4. Sebeteng, biotransformation ea metabolites e etsahala: li hlahisoa ka bongata, ho na le glucuronidation e sebetsang le hydroxylation. Ka lebaka la ts'ebetso ena, ho thehiloe li-metabolites tse 8 tse sa amaneng le tsoekere.
Ntho ena e tlosoa 'meleng ho tsoa lipelong (hoo e ka bang 70%) le ka mpeng (e ka bang 12%). Ho felisoa ha halofo ea bophelo ho etsa lihora tse 8-11.
Matšoao a ho sebelisoa
Setlhare sena se laeloa bakuli ba nang le lefu la tsoekere la mofuta oa 2 lefu le sa lekanyetsoang. E loketse ha mathata a hlaha (microangiopathy). Maemong ana, moriana o ka sebelisoa e le monotherapy kapa kalafo e rarahaneng hammoho le lithethefatsi tsa hypoglycemic.
Setlhare sena se laeloa bakuli ba nang le lefu la tsoekere la mofuta oa 2 lefu le sa lekanyetsoang.
Ha e le prophylactic, matlapa a khothalletsoa ho thibela nts'etsopele ea mathata a hemorheological ho lefu la tsoekere.
Contraindication
Lethathamo la li-contraindication ho moriana ona li kenyelletsa li-pathologies le maloetse a latelang:
- mofuta oa 1 lefu la tsoekere;
- nts'etsopele ea labile ea lefu la tsoekere la mofuta oa 2;
- ho ba teng ha insuloma ho mokuli;
- ketoacidosis;
- ho fokola ha rems le sebete;
- Microangiopathy e matla;
- hypersensitivity ho sulfonylurea;
- ho ima le ho nyekeloa ke mpa;
- mafu a tšoaetsanoang;
- nako ea mehato ea ho buoa pele le ka mor'a bona (lihora tse 48);
- bana ba ka tlase ho lilemo tse 18.
Ka tlhokomelo
Ho ea ka litaelo, ho na le maloetse a 'maloa le maemo ao ho' ona lengolo la ngaka le hlokang hore ho fetoloe litekanyetso le litekanyetso tsa tsamaiso. Hona ke:
- Psychology
- feberu
- tlhekefetso ea joala (botahoa);
- gland ha e sebetse hantle
- boteng ba lefu la tsoekere.
Ha ho na le methapo e le 'ngoe kapa tse' maloa tse boletsoeng ka holimo, ngaka e lokela ho khetha tsela ea phekolo ka bonngoe. Monyetla oa ho fana ka taelo ea Glidiab o nkoa.
Mokhoa oa ho nka Glidiab
Bakeng sa bonolo, ke moetlo ho khetholla litekanyetso tsa meriana tsa letsatsi le letsatsi:
- standard - 80 mg / letsatsi .;
- ka karolelano - 160 mg / letsatsi .;
- bophahamo ke 320 mg / letsatsi.
Bophahamo ba modumo ea letsatsi le letsatsi e arotsoe likarolo tse peli tse lekanang 'me e nkuoa hoseng le mantsiboea metsotso e 30 pele ho lijo. Noa moriana ona ka metsi a mangata.
Ho nka moriana oa lefu la tsoekere
Ha ho kgothaletswe ho ikatela, hobane moriana o thibetsoe mofuta oa 1 lefu la tsoekere le mofuta oa 2 bakeng sa nts'etsopele ea labile. Pele a fana ka tekanyetso, ngaka e hlahloba lilemo tsa mokuli, boemo ba lefu lena, matšoao a glycemia le tšebeliso ea lithethefatsi tse ling.
Pele a fana ka tekanyetso, ngaka e hlahloba lilemo tsa mokuli, boemo ba lefu lena, matšoao a glycemia le tšebeliso ea lithethefatsi tse ling.
Litlamorao tsa Glidaba
Litla-morao tse tlisoang ke ho sebelisa moriana li fumaneha seoelo. Maemong a mangata, matlapa a mamelletsoe hantle.
Bakuli ba ka tletleba ka:
- Ho tsekela
- hlooho e bohloko
- mokhathala;
- ho kula (ho hlohlona le urticaria);
- nts'etsopele ea lefu la ho tšoana le "disulfiram" (ho nyekeloa ke pelo, lets'ollo, kapa ho sokela);
- asthenia;
- photosensitization.
Tse sa tsejoeng hangata:
- paresis;
- hypoglycemia;
- thrombocytopenia;
- agranclocytosis;
- leukopenia;
- phokolo ea mali
Tšusumetso ho bokhoni ba taolo ea methapo
Ha ba sebelisa sethethefatsi sena, bakuli ba lokela ho ba hlokolosi ho khanna, ho sebelisa mechini le ho bapala lipapali tse ka bang kotsi.
Litaelo tse khethehileng
Ho fokotsa kotsi ea litla-morao, moriana o lokela ho beoa nakong ea tšebeliso ea lijo. Litlhokahalo tsa bohlokoa ke ho haella ha tlala ea sekoboto le ho khetholla joala ka botlalo.
Nako ea phekolo e etsoa hammoho le lijo tse nang le lik'habohaedreite tse nyane. Ka nako e ts'oanang, o hloka ho lekola khafetsa li-glucose tse maling ka mpeng e se nang letho le ka mor'a ho ja.
Ho fokotsa kotsi ea litla-morao, moriana o lokela ho beoa nakong ea tšebeliso ea lijo.
Maemong moo mokuli a nang le khatello e phahameng ea maikutlo kapa ea 'mele, litekanyetso tsa moriana li lokela ho lokisoa.
Sebelisa nakong ea bokhachane le pelehi
Setlhare ha se fuoe.
Ho rera Glidiab ho bana
Ka lebaka la hore ha ho na datha mabapi le likotsi le melemo ea moriana ho bana, ha e fuoe bakuli ba ka tlase ho lilemo tse 18.
Sebelisa botsofaling
Bakuli ba tsofetseng ha ba hloke phetoho ea litekanyetso. Mokhelo ke batho ba nang le li-pathologies tse hlokang tlhokomelo e eketsehileng.
Bakuli ba tsofetseng ha ba hloke phetoho ea litekanyetso.
Bongata ba Glidab
Ho eketsa tekanyetso ena ea kalafo e baka ho fokotseha ho matla hoa tsoekere ea mali. Liphetoho tse joalo li ka baka li-coma tsa hypoglycemic coma, lefu la tsoekere.
Ho tsitsa ho fokotsehile ho kenyelletsa tsoekere, sucrose kapa dextrose 'meleng. Ho na le mekhoa e mengata ea ho etsa sena:
- ka molomo (haeba motho a khona ho koenya);
- kahare (haeba mokuli a sa tsebe letho) - Tharollo ea 40% ea dextrose e fanoa.
Ntle le moo, 1-2 mg ea glucagon e fanoa ka intramuscularly. Kamora hore motho a hlaphoheloe kelellong, o bontšoa lijo tse nang le phepo e ntle ea lijo tse nang le phepo.
Ho eketsa tekanyetso ena ea kalafo e baka ho fokotseha ho matla hoa tsoekere ea mali.
Ho sebelisana le lithethefatsi tse ling
Ho khetha litekanyetso, ho lumellana ha lithethefatsi le lithethefatsi tse ling tse sebelisitsoeng kalafo ho lokela ho nahanoa.
Moriana ona ha o lumellane le litokisetso tsa miconazole.
Ketso ea "gliclazide" e sebetsang e ntlafatsoa ke lithethefatsi tse latelang:
- fibrate;
- Li-inhibitors tsa ACE;
- beta-blockers;
- biguanides (metformin);
- li-anabolic steroids;
- salicylates;
- MAO inhibitors;
- litopo;
- lithibela-mafu
- phosphamides;
- coumarins.
Tšusumetso ea lithethefatsi e fokotsoa ke lithethefatsi tse latelang ho tsoa lenaneng:
- glucocorticoids;
- barbiturates;
- sympathomimetics;
- lihormone tsa qoqotho;
- saluretics;
- letsoai la lithium;
- Rifampicin;
- Chlorpromazine;
- Glucagon.
Methapo e phahameng ea estrogen, lithibela-pelehi tsa molomo, acid ea nicotinic e ka fokolisa matla.
Tekanyo ea joala
Nakong ea kalafo le Glidiab, joala bo lokela ho tloheloa ka ho felletseng. Ha e kopantsoe, katleho ea moriana e tlase. Ntle le moo, boteng ba ethanol bo eketsa kotsi ea litla-morao.
Li-analog
Setlhare sa mantlha sa sehlopha sena ke Gliclazide (e na le sehlahisoa se sebetsang sa lebitso le le leng). Lithethefatsi tse ling tsohle tse nang le motsoako ona li nkuoa e le li-generator. Lithethefatsi tse latelang li fetisetsoa ho li-antidiabetesic agents tse nang le gliclazide:
- Diatics;
- Tlhokomeliso;
- Diabefarm;
- Diabinax;
- Predian;
- Diabresid;
- Gliklada;
- Diabetesalong;
- Glucose;
- Predian;
- Glioral;
- Diabresid;
- Glucostabil;
- Medoclazide.
Hona le litlhare tse 'maloa tse tsamaisanang le morero (mofuta oa 2 lefu la tsoekere). Har'a tsona ke tse 'maloa tse batloang haholo ka mora mona:
- Januvius;
- Glucobay;
- Bagomet;
- Baeta;
- Lymphomyozot;
- Avandia
- Methamine;
- Multisorb;
- Foromo.
Lipehelo tsa khefu ea khemisi
O ka reka sethethefatsi sena ka k'hemisteng feela ka taelo ea ngaka.
Mofuta oa Glidiab
Litsenyehelo tsa lithethefatsi li fapana hanyane ho latela leano la litheko tsa k'hemiste. Naheng ea Moscow, theko e tsoa ho li-ruble tse 120 ho isa ho tse 160.
O ka reka sethethefatsi sena ka k'hemisteng feela ka taelo ea ngaka.
Maemo a polokelo ea moriana
Setlhare se khethiloe e le B. E lokela ho bolokoa sebakeng se lefifi hole le bana ka mocheso o sa feteng + 25 ° C.
Letsatsi la ho felloa ke nako
Nako ea polokelo ke lilemo tse 4. Kamora nako ena, mori o thibetsoe ho nka.
Moqapi
Moqapi ke k'hamphani ea Russia Akhirin Khimfarmkombinat OJSC. Ofisi le tlhahiso ea k'hamphani li sebakeng sa Moscow, motsana oa Staraya Kupavna.
Litlhahlobo tsa Glidiab
Irina, ea lilemo li 49, Tyumen
Ke se ke qetile selemo ke noele Glidiab, boemo ba ka bo se bo tsitsitse. Ho lekana: o noa pilisi hoseng 'me o ka ea mosebetsing ka mokhoa o sireletsehileng mme o sa tšoenyehe ka tsoekere. Ntho feela e sa lokelang ho lebaloa ke lijo tse matlafatsang. Ho seng joalo, moriana o se o se na thuso.
Natalia, ea lilemo li 35, Izhevsk
Ka nakoana ke ile ka noa sethethefatsi se seng ka mofuta o tšoanang. Likhoeli tse 'maloa tse fetileng, ngaka e ile ea fetisetsa Glidiab. Pele, ho ne ho baka tsitsipano e nyane ka mpeng. Kamora libeke tse 'maloa, litla-morao li ile. Ke ntse ke sebelisa lipilisi tsena. Ho fihla joale, tsohle li hantle.
