Neurobion ke sethethefatsi sa kajeno sa multivitamin. Phello ea kalafo ea lithethefatsi e bakoa ke thiamine, pyridoxine le cyanocobalamin. Hangata lingaka li fana ka litlhare ho phekola mafu a tsamaiso ea methapo.
ATX
A11DB (livithamini B1, B6 le B12).
Neurobion ke sethethefatsi sa kajeno sa multivitamin.
Lokolla liforomo le sebopeho
Ka 'marakeng oa litlama oa naha ea rona, lithethefatsi li ka rekoa ka matlapa le li-ampoules tsa 3 ml.
Lipilisi
Matlapa ana ke biconvex, e koahetsoeng ka khetla e tšoeu e bosootho holimo. Sebopeho sa lik'hemik'hale tsa moriana se hlahisoa litafoleng.
| Motsoako | Letlapa le leng le na le mg |
| Cyanocobalamin | 0,24 |
| Pyridoxine hydrochloride | 0,20 |
| Thiamine disulfide | 0,10 |
| Hlakola | 133,22 |
| Starch ea poone | 20 |
| Magnesium stearate | 2,14 |
| Metocel | 4 |
| Lactose Monohydrate | 40 |
| Glutin | 23,76 |
| Silica | 8,64 |
| Mountain glycol wax | 300 |
| Arab ea makhopho | 1,96 |
| Povidone | 4,32 |
| Calcium calcium | 8,64 |
| Kaolin | 21,5 |
| Glycerol 85% | 4,32 |
| Tekanyetso ea titanium | 28 |
| Talcum phofo | 49,86 |
Matlapa ana ke biconvex, e koahetsoeng ka khetla e tšoeu e bosootho holimo.
Tharollo
Moriana bakeng sa tšebeliso ea botsoali ke mokelikeli o hlakileng o mofubelu.
| Motsoako | Ampoule e le 'ngoe e na le mg |
| Cyanocobalamin | 1 |
| Pyridoxine hydrochloride | 100 |
| Thiamine hydrochloride | 100 |
| Sodium hydroxide | 73 |
| Potasiamo cyanide | 0,1 |
| Koahela metsi | ho fihla ho 3 cm3 |
Ketso ea pharmacological
Li-vithamine tsa sehlopha B, tse kenyellelitsoeng ka sebopeho sa moriana, li-catalyze redox process, li laola metabolism ea lipids, liprotheine le lik'habohaedreite. Lithako tsena, ho fapana le li-analogue tse haelloang ke metsi ha li kenngoe 'meleng oa motho, ka hona, li tlameha ho kenella khafetsa' me ka bongata bo lekaneng bo kena 'meleng ka lijo kapa e le karolo ea tlatsetso ea vithamine-mineral. Le haeba ho fokotseha ha nako ea bona ka nako e khuts'oane ho fokolisa tšebetso ea lits'ebetso tsa enzyme, tse sitisang ho fetoha hoa metaboliki le ho fokotsa boits'ireletso ba mmele.
Li-vithamine tsa sehlopha B, tse kenyellelitsoeng ka har'a sebopeho sa lithethefatsi, li-catalyze redox process.
Mofumahali
Ka khaello ea thiamine 'meleng, ts'ebetso ea phetoho ea pyruvate ho activate acetate acid (acetyl-CoA) e sitisoa. Ka lebaka la sena, li-keto acid (α-ketoglutarate, puruvate) li bokellana maling le liseleng tsa litho, tse lebisang ho "acidization" ea 'mele. Acidosis e hlaha ha nako e ntse e feta.
Metabolite ea bioactive metabolite ea vithamine B1, thiamine pyrophosphate, e sebetsa e le protheine e se nang protheine ea li-decarboxylase tsa pyruvic le α-ketoglutaric acids (i.e. e nka karolo ho bonts'eng ha oxidation ea carbohydrate). Acetyl-CoA e kenyelelitsoe mokelikeling oa Krebs 'me e entsoe ka metsi le carbon dioxide, ha e ntse e le mohloli oa matla. Ka nako e ts'oanang, thiamine hydrochloride e ameha ho hlahisoeng ha mafura acid le cholesterol, e kenya ts'ebetsong ts'ebetso ea ho fetola lik'habohaedreite hore e be mafura.
Ha ho fanoa ka molomo, halofo ea bophelo ea vithamine B1 e ka ba lihora tse 'ne.
Ha ho fanoa ka molomo, halofo ea bophelo ea vithamine B1 e ka ba lihora tse 'ne. Sebeteng, thiamine e phosphorylated 'me e fetoloa ho thiamine pyrophosphate. 'Mele oa motho e moholo o na le vithamine B1 e ka bang 30 mg. Kaha e na le metabolism e matla, e hloekisoa 'meleng ka matsatsi a 5-7.
Pyridoxine ke karolo ea sebopeho sa li-coenzymes (pyridoxalphosphate, pyridoxamine phosphate). Ka khaello ea vithamine B6, phapanyetsano ea li-amino acid, li-peptide le liprotheine lia senyeha. Maling, palo ea lisele tse khubelu tsa mali ea fokotseha, hemostasis ea senyeha, karolelano ea liprotheine tsa serum ea fetoha. Maemong a tsoetseng pele haholo, khaello ea livithamini tse qhibilihang ka metsing li lebisa phetohong ea methapo letlalong. 'Mele o na le hoo e ka bang 150 mg ea pyridoxine.
Ka khaello ea vithamine B6, phapanyetsano ea li-amino acid, li-peptide le liprotheine lia senyeha.
Pyridoxalphosphate e ameha ho thehoeng ha li-neurotransmitters le lihormone (acetylcholine, serotonin, taurine, histamine, tryptamine, adrenaline, norepinephrine). Pyridoxine e boetse e kenya tšebetsong biosynthesis ea sphingolipids, likarolo tsa sebopeho sa li-myelin sheaths tsa methapo ea methapo.
Cyanocobalamin ke vithamine e nang le tšepe e potlakisang ho etsoa ha lisele tse khubelu tsa mali, e hlahisang li-enzyme tsa sebete tse thusang ho feto-fetoha ha carotenoids ho khutlela morao.
Vitamin B12 e hlokahala bakeng sa motsoako oa deoxyribonucleic acid, homocysteine, adrenaline, methionine, norepinephrine, choline le moeine. Karolo ea cyanocobalamin e kenyelletsa cobalt, sehlopha sa nucleotide le radical cyanide. Vithamine B12 e kenngoa haholo-holo ka har'a sebete.
Vitamin B12 e hlokahala bakeng sa motsoako oa deoxyribonucleic acid.
Matšoao a ho sebelisoa
Moriana o laetsoe kalafo ea li-pathologies tse latelang:
- radiculopathy;
- thoracalgia;
- mafu a lesapo la mokokotlo (spondylarthrosis, osteochondrosis, spondylosis);
- lefu la neuropathic;
- herpes zoster;
- trigeminal neuralgia;
- lefu la lumbar;
- Bell palsy;
- plexopathy.
Contraindication
Lithethefatsi li na le litlolo tse 'maloa tse lebisitsoeng ho motho eo a e behiloeng:
- thromboembolism;
- lilemo tsa bana;
- erythremia;
- hypersensitivity;
- seso sa ka mpeng;
- allergy
U ka e nka joang
Ho thibela ho hlaha hoa mafu a ka bocha a lefu lena, moriana o ngotsoe ka sebopeho sa letlapa, makhetlo a 1 ka makhetlo a mararo ka letsatsi. Ha u nka matlapa, u hloka ho a noa ka metsi a mangata. Nako ea thuto e khethiloe ke ngaka.
Moriana ho ampoules o fanoa bakeng sa tsamaiso ea methapo ea methapo. Pele o tlosa matšoao a mantlha a lefu lena, ho khothalletsoa ho enta moriana o le mong ka letsatsi. Kamora ho ikutloa u le betere, liente li etsoa hang ka beke bakeng sa libeke tse 2-3.
Le lefu la tsoekere
Sesebelisoa se ka holimo se molemo ho phekola bohloko ba neuropathic ho bakuli ba nang le lefu la tsoekere la polyneuropathy. Ho ile ha fumaneha hore lithethefatsi li fokotsa botebo ba paresthesia, e ntlafatsa ho sithabela ha letlalo, e imolla bohloko.
Ho thibela ho hlaha hoa mafu a ka bocha a lefu lena, moriana o ngotsoe ka sebopeho sa letlapa, makhetlo a 1 ka makhetlo a mararo ka letsatsi.
Litlamorao
Moriana o mamelloa hantle ke bongata ba bakuli. Leha ho le joalo, maemong a mang, lipontšo tsa litla-morao tse arotsoeng ka lihlopha lia khonahala.
Phekolo ea ka mpeng
- bothata ba ho koenya;
- ho hlatsa
- hemorrhage ka mpeng;
- bohloko ba ka mpeng;
- ho nyekeloa
- botumo;
- lets'ollo
Ho tsoa ho sesole sa 'mele
- Edema ea Quincke;
- dermatitis;
- eczema
- anaphylactoid reaction.
Allergie
- makhopho
- ho hlohlona
- hyperemia;
- ho ruruha ho feteletseng;
- bohloko
- makhopho
- urticaria;
- necrosis sebakeng sa ente.
Tsamaiso ea pelo
- pelo lippitations;
- bohloko ba sefuba.
Tsamaiso ea methapo
- hyper irritability;
- migraine
- sensory neuropathy;
- paresthesia;
- Ho sithabela maikutlo
- ho tsekela.
Litaelo tse khethehileng
Setlhare ha se reretsoe tsamaiso ea methapo. Hape, sethethefatsi se ke ke sa sebelisoa ho bakuli ba nang le lefu la pelo le matla. Ka tlhokomeliso e fetelletseng, meriana e lokela ho fuoa batho ba nang le neoplasms e mpe.
Setlhare ha se reretsoe tsamaiso ea methapo.
Tšusumetso ho bokhoni ba taolo ea methapo
Setlhare sena ha se ame bokhoni ba motho ba ho khanna makoloi le mekhoa e rarahaneng.
Sebelisa nakong ea bokhachane le pelehi
Nakong ea ho ba le bana, sehlahisoa se ka sebelisoa feela haeba ho na le matšoao a hlakileng a khaello ea livithamini B1, B6 le B12 'meleng oa mme ea lebelletsoeng. Litlamorao tsa moriana ho ima, pele ho pelehi le kamora ngoana ha li e-so fumanoe.
Ngaka e lokela ho tseba ho nepahala ha ho fana ka moriana nakong ea kemolo, ho tseba kamano pakeng tsa melemo le kotsi.
Li-vithamine tse etsang moriana ona li hlahisoa ka lekunutu la litšoelesa tse anyesang, leha ho le joalo, kotsi ea hypervitaminosis ho masea ha e so tsebisoe. Ho amoheloa ha pyridoxine ka tekanyetso e kholo (> 600 mg ka letsatsi) ho ka tsosa hypo- kapa agalactia.
Nakong ea ho ba le bana, sehlahisoa se ka sebelisoa feela haeba ho na le matšoao a hlakileng a khaello ea livithamini B1, B6 le B12 'meleng oa mme ea lebelletsoeng.
Ho khethoa ha neurobion ho bana
Bana ba ka tlase ho lilemo tse 15 ha ba khothalletsoe ho fana ka moriana.
Sebelisa botsofaling
Tlhahisoleseling mabapi le ts'ebeliso ea lithethefatsi ho batho ba tsofetseng le senile ha e fumanehe.
Bongata
Ka har'a lingoliloeng tse ikhethang, ho hlalosoa linyeoe tsa lithethefatsi tse feteletseng tsa lithethefatsi. Bakuli ba tletleba ka bophelo bo botle, mesifa e bohloko, manonyeletso, ho nyekeloa le pelo le mokhathala o sa foleng. Haeba u fumana matšoao a ka holimo, moriana o lokela ho hlakoloa ebe o etela ngaka. O tla fumana sesosa sa mathata, ho fana ka kalafo ea matšoao.
Vithamine B1
Kamora ho hlahisoa ha thiamine ka lethal dose e fetisang makhetlo a fetang lekholo, ho ts'oaroa ha hypercoagulation, ho senyeha ha purine metabolism, litlamorao tsa curariform ganglioblocking tse bakang tšilafalo ea tlhahiso ea litšusumetso tse haufi le methapo ea methapo.
Ho ikutloa o sa sebetse, bofokoli bo akaretsang ke matšoao a bosholu ba moriana.
Vithamine B6
Kamora ho amoheloa ka nako e telele (ho feta likhoeli tse tšeletseng) tsa pyridoxine ka tekanyo ea ho feta 50 mg / ka letsatsi, pontso ea litla-morao tsa neurotoxic (hypochromasia, seborrheic eczema, lefu la sethoathoa, neuropathy le ataxia) lia khoneha.
Vithamine B12
Haeba ho na le ts'oaetso e feteletseng, ho kula ho bakoang ke ho kula, ho hlohlona, ho hloka boroko, khatello e phahameng ea mali, ho hlohlona, khatello ea methapo e tlase, lets'ollo, phokolo ea mali le ho makala.
Ho sebelisana le lithethefatsi tse ling
Litaelo tsa tšebeliso li bontša hore lithethefatsi tse ling ha li lumellane le sethethefatsi se kaholimo. Ka linako tse ling, tsamaiso e ts'oanang e lebisa ho fokolisang matla a kalafo kapa ho eketsa ponahatso ea litlamorao:
- Thiamine e senngoa ka ho sebelisana le meriana e nang le sulfite (potasiamo metabisulfite, potasiamo bisulfite, sodium hydrosulfite, sodium sulfite, jj).
- Tšebeliso e kopaneng ea cycloserine le D-penicillamine e eketsa tlhoko ea 'mele ea pyridoxine.
- Setlhare ha sea lokela ho kopanngoa le meriana e meng ka har'a siling e le 'ngoe.
- Tsamaiso ea li-diuretics e lebisa ho fokotseha ha palo ea vithamine B1 maling mme e potlakisa haholo tlhahiso ea eona ea liphio.
Setlhare ha sea lokela ho kopanngoa le meriana e meng ka har'a siling e le 'ngoe.
Mokuli o lokela ho tsebisa ngaka ka meriana eo a e noang hona joale. Ngaka ntlheng ena e tla ntlafatsa mofuta oa kalafo, ka hona a fokotsa menyetla ea litla-morao.
Li-analog
Haeba ho hlokahala, moriana o ka nkeloa sebaka ke mekhoa e kang:
- Neurolek;
- Kombilipen;
- Milgamma
- Vitaxone;
- Neuromax;
- E nepahetse;
- Neuromultivitis;
- Esmin;
- Neurobeks-Teva;
- Selmevite;
- Dynamizan;
- Unigamm
- Kombilipen;
- Centrum;
- Pantovigar;
- Farmaton
- Ginton;
- Nerviplex;
- Aktimunn;
- Berocca le;
- Encaps;
- Detoxyl
- Pregnakea;
- Neovitam;
- motsoako oa livithamini B1, B12, B6;
- Megadine;
- Neurobeks-Forte.
Moqapi
Moqapi oa semolao ea lithethefatsi ke Merck KGaA (Jeremane).
Lipehelo tsa khefu ea khemisi
Lifekthering, pheko ena e fuoa meriana e fanoang, empa ha se setlhare se khothalletsoang ka mokhoa o thata.
Theko ea Neurobion
Litsenyehelo tsa lithethefatsi tsa Russia li fapana ka theko ho tloha ho li-ruble tse 220 ho isa ho tse 340. Ukraine - 55-70 UAH. bakeng sa ho paka.
Maemo a polokelo ea lithethefatsi Neurobion
Boloka lithethefatsi sebakeng se lefifi le se phodileng.
Letsatsi la ho felloa ke nako
Lilemo tse 3
Tlhahlobo ea lingaka le bakuli mabapi le Neurobion
Svetlana o lilemo li 39, Kiev: "Ke bile le mathata a lesapo la mokokotlo ho tloha ha ke le lilemo li 18. Osteochondrosis o ile a fuoa li-vithamine ka ente .. Moriana o ile oa enta ka methapo ea kutlo, 1 ampoule ka letsatsi. Kamora thupelo ea libeke tse peli, bophelo ba ka bo ile ba ntlafala le bohloko sebakeng se lumbar. Bakeng sa merero ea prophylactic, ke sebelisa moriana o ka mokhoa oa letlapa.
Andrei ea lilemo li 37, Astrakhan: "Haufinyane tjena ba ile ba qala ho tšoenyeha ka ho hlohlona ho tebileng le bohloko sebakeng sa mesifa. Ha ngaka e beoa, o ile a fumana hore ke na le radicular neuritis. Ngaka ea methapo ea kutlo e ile ea tsoa likotsi tsa Neurobion. Ho se utloane hohle ho ile hanghang ka mor'a matsatsi a mane. Ho ne ho laetsoe ampoule e le 'ngoe ka beke. Ke khotsofetse ke sephetho sa kalafo. "
Sabina ea lilemo li 30, Moscow: "Ke sebelisitse livithamini bakeng sa lumbar neuralgia nako e telele. Kamora nako e itseng, ba ile ba emisa ho thusa. Ha ke ea ngakeng, o ile a kenella Neurobion. Kamora matsatsi a 'maloa ke phomotse. Kamora ho hlaphoheloa, ke tla e sebelisa hape e le prophylactic. moriana ka mokhoa oa matlapa. "
Artyom ea lilemo li 25, Bryansk: "O sebelisitse motsoako oa vithamine kalafo ea neuro-brachial syndrome. O ile a fana ka liente ka matsatsi a 5. Setlhare sena se ile sa fokotsa litlhaselo tsa bohloko mme sa khutlisa mmele ka tekanyo e hlokahalang ea livithamini. Kamora thupelo ea libeke tse tharo, ngaka e neng e iletse lipilisi hore e sebelisoe ka mehla. e sebelisitsoe joalo ka kalafo ho hlokomela ho khutla hape. "
