Diabetesic Microangiopathy: matšoao, kalafo, litlamorao

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Haeba u hlophisa tlholisano har'a maloetse ohle, sebaka sa pele khafetsa ho mathata, ho teba ha kalafo ea bona, litlamorao ho mokuli, ntle le pelaelo, li tla tlameha ho fa lefu la tsoekere. Mathata a mangata a thehiloe ho lefu la tsoekere la tsoekere. Ka lebaka la phello ea tsoekere likepeng tse nyane, li fetoha brittle ebile li senngoa habonolo. Ka lebaka leo, libakeng tse ling kholo e sa laoleheng ea marang-rang a capillary e qala, athe libaka tse ling ha li na phepelo ea mali ka botlalo.

Selemo se seng le se seng, ka lebaka la lefu la Microangiopathy, ho etsoa likoto tse milione tsa maemo a tlase, batho ba nang le lefu la tsoekere ba limilione tse 0,6 ba sa bone, 'me liphio li sebetsa ho bakuli ba limilione tse 0.5. Boholo ba litlolo bo ka sebetsanoa le tsona haeba li ka fumanoa maemong a pele.

Sengoloa se akaretsang mabapi le angiopathy se teng mona - //diabetiya.ru/oslozhneniya/diabeticheskaya-angiopatiya.html

Lefu la tsoekere le khatello e matla e tla ba ntho ea khale

  • Ts'oarelo ea tsoekere -95%
  • Ho felisoa ha vein thrombosis - 70%
  • Ho felisa ho otla ha pelo e matla -90%
  • Ho tlosa khatello e phahameng ea mali - 92%
  • Keketseho ea matla mots'eare, ho ntlafatsa boroko bosiu -97%

Lefu la tsoekere le lefu la tsoekere - ke eng

Microangiopathy ke pheko e sa foleng ea lefu la tsoekere. Lebaka la eona le ka sehloohong ke phello ea tsoekere e phahameng ea mali holim'a bokantle ba marako a methapo ea mali. Glucose limolek'hule tsa "glycate endothelial" liprotheine, ke hore, li tlameletsoe ho tsona. Ts'ebetso ena e tsamaisana le tahlehelo ea methapo ea methapo, ho fokotseha ha bona, ho eketseha ha bona hape ebe timetso. Boemo bo mpefatsoa ke khatello ea ts'oaetso ea oxidative - tšenyo ea lisele ka li-radicals tsa mahala, tseo ho tsona lefu la tsoekere le hlahisoang ka bongata bo eketsehileng. Tlolo ea metabolism ea lipid, tšobotsi ea lefu la tsoekere la 2, le eona e na le litlamorao tse mpe maemong a methapo ea mali.

Litho tsohle tsa rona li kenngoe ke marangrang a likepe tse nyane, ka hona, lefu la tsoekere la tsoekere le ka senya ts'ebetso ea efe kapa efe ea tsona. Hangata, li-retina le lintla tsa liphio li fetoha "liphofu", hobane khokahano e hlophisitsoeng hantle ea li-capillaries e bohlokoa bakeng sa ts'ebetso ea bona e tloaelehileng.

Mathata a lefu la tsoekere, nts'etsopele ea eona e ts'oenyang microangiopathy:

BoloetseTlhaloso
RetinopathyLikepe tse fepelang retina li senngoa ka ho etsoa ha edema le ho bola, e lebisang ho senyeha ha pono. Haeba kalafo e sa qale ka nako, ho tla senyeha mokokotlo oa mokokotlo, ho senyeha ha methapo ea kutlo, le tahlehelo e felletseng ea pono.
NephropathyMicroangiopathy ho lefu la tsoekere mellitus e sitisa ts'ebetso ea glomeruli ea renal, e amang bokhoni ba bona ba ho ntša urine. Letšoao la pele ke protheine ka har'a moroto. Mosebetsi oa liphio butle-butle oa mpefala ho fihlela ho sebetsoa ke pheko.
Microangiopathy ea likarolo tse tlaseMaoto a phahame haholo ho tloha pelong, kahoo ho potoloha ha mali a 'ona ha ho na matla,' me kotsi ea lefu la tsoekere ea lefu la tsoekere e holimo haholo. Liphetoho tsa methapo ea kutlo li qala ka tlolo ea phallo ea mali ka menoaneng, mme le ka leoto lohle. Ho haella ha phallo ea mali ho lebisa ho bolaoa ke tlala ea litho tsa 'mele, ho ferekanya lefu la tsoekere, ho fokotsa bokhoni ba lisele tsa ho hlaphoheloa, hape ho thusa ho ntlafatseng leoto la lefu la tsoekere.
EncephalopathySena ke leseli la bokong, hangata le bakoa ke ho ruruha ha methapo ea pelo. Worsen encephalopathy neuropathy le lipids tse phahameng tsa mali ho lefu la tsoekere.
Ho hloka thobalano ho bannaHammoho le neuropathy, microangiopathy ke e 'ngoe ea lisosa tsa ho hloka matla. Ho senyeha ha erection ho diabetics hangata ho amahanngoa le ho se lekane ho tlatsa setho ka mali.

ICD Code 10 bakeng la lefu la tsoekere la Microidiopathy:

  • 2; E11.2 - nephropathy;
  • 3; E11.3 - retinopathy;
  • E5; E11.5 - Mathata a mang a bakoang ke ho se sebetse hantle ha methapo ea letsoho.

Matšoao a Microangiopathy ho lefu la tsoekere

Maemong a mangata, ha ho na matšoao qalong ea lefu lena. Ha u ntse u tsoela pele, mokuli ea nang le lefu la tsoekere a ka hlokomela:

  • pono e lerootho ea nakoana;
  • matheba a phaphametseng pela mahlo, a nyamela kamora matsatsi a mmalwa;
  • matšoao a botaoa - bofokoli, mokhathala, ho hloka takatso ea lijo;
  • moroto o eketsehileng - bala ka polyuria;
  • bosiu, bladder e tlala hangata ho feta pele;
  • Liphetoho maemong a maikutlo a mokuli: Ho lla ho ea mpefala, likarolo tsa ho teneha ntle le tšohanyetso li hlaha, kapa ho fapana le hoo, ho se tsotelle liketsahalo tse bohlokoa tsa pele;
  • mohlomong o ikutloa a le motenya litempeleng, hlooho e bohloko. Matšoao ha a felle ka botlalo ka mor'a ho nka li-painkiller;
  • mathata a ho hopola le ho teba;
  • menoana e lula e bata;
  • maqeba letlalong, haholo makaleng a tlase, u se ke oa fola nako e telele;
  • ho senyeha ha potency - ho hloka matla ha lefu la tsoekere.

Phekolo ea microangiopathy e sebetsa hantle haholo qalong, ha matšoao a eona a ntse a le sieo, ka hona, haeba ho ka ba le lefu la tsoekere. Se ke oa tlola tlhatlhobo ea bongaka ea nako le nakoe laetsoe ke ngaka e eang. Ntho ea bohlokoa ka ho fetisisa ke ho etela ngaka ea mahlo, lephrologist le neurologist.

Ts'oaetso

Mehato ea ho khetholla ho bona microangiopathy ho lefu la tsoekere e kenyeletsa:

  1. Tlhahlobo ea biochemical ea morine bakeng sa albin e khona ho bona protheine moriring pele ho feta OAM. Boemong ba pele, ha e abeloe kamehla, ka hona ho molemo ho fana ka moroto ka letsatsi.
  2. Nephropathy e tsamaisana le renal hypertrophy, e ka bonoang ke ultrasound.
  3. Hoa khoneha ho bona retinopathy le pele ho matšoao a pele ha u hlahloba fundus - ophthalmoscopy, haeba ho sa khonehe ho e tsamaisa, ho sebelisoa ultrasound.
  4. Ho haella ha ho potoloha ha mali ho li-capillaries tsa liphula tse tlase ho qetoa habonolo ka pono: libaka tse ling tsa letlalo li boreleli ebile li pholile, tse ling li le bokhubelu ka lebaka la kholo ea li-capillaries. Feela, mokato oa letlalo le sa sikoang oa eketseha, makhopho a hlaha.
  5. Tekanyo ea "di" Microangiopathy "ea" diabetes "maotong e ka hlahlojoa ho sebelisoa capillaroscopy kapa thuto ea sejoale-joale e theko e phahameng - flowopry ea Doppler.
  6. MRI e sebelisoa ho bona phetoho phepelong ea mali ho ea bokong.

Mokhoa oa ho phekola complication

Boemo bo ka sehloohong ba kalafo e atlehileng ea microangiopathy ke puseletso e tsitsitseng ea lefu la tsoekere. Ho fumanoe hore ho fokotseha ha hemoglobin ea glycated ea 1% feela ka karolo ea boraro ho fokotsa kotsi ea tšenyo ea methapo. Hoa khoneha ho thibela microangiopathy le ho fokotsa mathata a teng a lefu la tsoekere la mefuta e 'meli feela ka thuso ea ho lekola glycemia kamehla. Ho feta moo, ha ho na taba hore sepheo sena se fihlelloa joang. Haeba u boloka tsoekere e le tloaelo, lijo tse nang le nama e tlase ea carb lia thusa - ho lokile. Haeba ho hlokahala kalafo e matla ea insulin ho fumana matšeliso a lefu la tsoekere, o tla tlameha ho fetohela ho ona. Leha ho le joalo, hyperglycemia e kotsi haholo ho feta litlamorao tse tlisoang ke lithethefatsi tse theolelang tsoekere.

Ke 'mele feela o ka lokisang marang-rang a senyehileng a likepe. Mosebetsi oa kalafo ke ho mo thusa ntlheng ena e thata.

Bakeng sa sena, ho bakuli ba nang le ts'ebeliso ea lefu la tsoekere:

  1. Mekhoa ea sejoale-joale ea ho fokotsa khatello ea mali ka har'a lijana ke li-block tsa ACE le li-blockers tsa AT1.
  2. Li-ejenti tse kantle tse nang le litlamorao tsa antibacterial le regenerative bakeng sa kalafo e potlakileng ea maqeba maotong.
  3. Boikoetliso ba 'mele ho ntlafatsa phallo ea mali.
  4. Li-antioxidants tsa ho imolla khatello ea oxidative (Thiogamma).
  5. Barekisi ba microcirculation (Actovegin, Curantil).
  6. Lipalo haeba boemo ba lipid tsa mali bo sa hole haholo.
  7. Li-vithamine, haholo-holo sehlopha sa B.
  8. Lithethefatsi tsa ho fokotsa mali le thibelo ea thrombosis (Lioton, Heparin).

Mefuta e tebileng le litlamorao

Haeba microangiopathy e bonolo e arabela hantle kalafong, mehato ea lefu lena e ke ke ea phekoloa ka botlalo. Maemong ana, e ka ba poloko e lekanyelitsoeng ea litho tsa litho tse senyehileng ke lefu la tsoekere.

Liphetho tsa angiopathy:

BoloetsePhello e ka ba e mpe
RetinopathyHo koaloa hape ka mokokotlo, glaucoma, ho lahleheloa ke pono haholo, bofofu bo felletseng.
NephropathyPhokotso ea ts'ebetso ea liphio, khatello ea mali, edema, tahi, ho se sebetse hantle ka mpeng, tlhoko ea ho hlohlona kapa ho fetisoa hoa litho.
Leoto la lefu la tsoekereLi-ulcophara, tšilafalo ea manonyeletso le masapo a masapo, maqeba, ho khaoloa leoto kapa leoto le ka tlase, sepsis.
EncephalopathyMigraine, cramps, ho holofala, amnesia, mathata a kelello.
Ho se sebetse hantle ha kelelloHo se sebetse hantle ha erectile dysfunction.

Tšepa bophelo bo botle 'me u se ke ua lebala ho etela litsebi ka nako bakeng sa ho lemoha li-pathologies kapele.

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