Mofuta oa 2 oa lefu la tsoekere, manyeme oa senyeha, menyetla ea ho fetoha ha litho tsa 'mele ho "insulin ea" hormone ea fokotseha. Phekolo e tšoanang le ena hangata e fumanoa hangata ho batho ba fetang lilemo tse 45.
Phekolo ea lefu lena e na le ho nka moriana o theolelang tsoekere, ngaka e boetse e fana ka phepo e khethehileng ea kalafo le litekanyetso tsa boikoetliso ba 'mele. Pele ho tsohle, batho ba nang le lefu la tsoekere ba lokela ho nahanisisa ka tsela eo u phelang ka eona, ho ntlafatsa lijo tse nang le phepo le ho eketsa ts'ebetso ea makoloi.
Ho netefatsa hore maemo a tsoekere ea mali a tloaelehile, ho fanoa ka lipilisi tse fokotsang tekanyo ea tsoekere maling. Setlhare se khutlisetsa ho senyeha ha lisele ka hanong, se fokotsa tekanyo ea ho kenella ka har'a insulin kahare, se fokotsa tlhahiso ea tsoekere ka lisele tsa sebete, 'me se fokotsa cholesterol.
Ho fokotsa Lithethefatsi
Lithethefatsi tsohle tsa kalafo ea lefu la tsoekere la mofuta oa 2 li ka aroloa ka lihlopha tse 'maloa ho latela molaoana oa tšebetso ea bona. Tsena li kenyelletsa li-biguanides, li-sulfanilurea derivatives, li-insretin, alpha glucosidase inhibitors, li-thiazolidinone derivatives, dipeptidyl peptidiase 4 inhibitors, GLP-1 receptor agonists.
Li-Biguanides li etsa hore lisele tse potolohang li amehe habonolo ke insulin, li fokotsa tlhahiso ea li-hormone, hape li fetole takatso ea lijo. Tsena li kenyelletsa matlapa a Siofor le Metformin. Nakong ea kalafo, lefu la tsoekere le fokotseha boima ba 'mele, lipid metabolism e thatafala. Hangata moriana o baka litlamorao ka mokhoa oa ho hlohlona lijo tse tsoileng matsoho, ka hona, moriana o nooa ka tekanyetso e lekanyelitsoeng kamora feela ho buisana le ngaka.
Hangata, mofuta oa 2 lefu la tsoekere le phekoloa ka lintho tse tsoang ho sulfonylurea - litokisetso tsa Chlorpropamide, Starlix, Glimepiride, Tolbutamide, Diabetes. Lithethefatsi tse joalo li khothaletsa tlhahiso ea lihormone ke lisele tsa manyeme le ho fokotsa ho hlaseloa ha lisele tsa mmele ho insulin. Lithethefatsi tse joalo li ka hlakola manyeme, kahoo haeba litekanyetso li fosahetse, e lebisa ho hypoglycemia.
- Meriana Insulinotropic polyptipid le Enteroglucagon li khetholloa ke boteng ba li-insretin - lihormone tsa tsamaiso ea tšilo ea lijo, tlhahiso ea tsona e bang teng kamora hore motho a jele. Lihormone tsena li baka tlhahiso ea insulin ke manyeme. Ka lilemo, thepa ena ea lisele e fokotseha ho motho, e sebelisa lithethefatsi ho khutlisa tšebetso ena.
- Li-inhibitors tsa Alpha-glucosidase ha li lumelle lik'habohaedreite hore li kenngoe ka mpeng e nyane, ka hona li fokotsa glycemia kamora ho ja le ho fokotsa tlhoko ea tlhahiso ea insulin. Li-glucobai, Miglitol, Acarbose, matlapa a Voglibosis li ngotsoe e le moriana o eketsehileng.
- Ka lebaka la melemo ea thiazolidinone, ho hanyetsa ha li-insulin receptor ho eketseha, tsoekere ea mali e ea fokotseha, metabolism ea lipid e khutlisetsoe, ho tlosoa ha glucose e fetelletseng 'meleng ho potlakile. Lithako tsa cholesterol e phahameng le e tlase haholo le tsona lia eketseha. Tse tummeng ka ho fetisisa ke Pioglitazone le Rosiglitazone. Sehlopha sena sa lithethefatsi se baka litlamorao tse ngata mme se eketsa boima ba 'mele.
- Ho eketsa karabelo ea cellular ea manyeme ho ea tsoekere, hemoglobin e tlase le triglycerides maling, ho sebelisoa kalafo e thibelang lipeptidyl peptidiasis 4. Ka thuso ea Sitagliptin, Vildagliptin, lefu la tsoekere le ka laola glycemia. Setlhare sena se nkuoa ka bobeli ka boikemelo le ka kopanelo le Metformin.
- Ho laola takatso ea hau ea lijo, ngaka ea hau e ka fana ka lefu la tsoekere ho nka li-agonists tsa GLP-1 receptor. Setlhare sena se khotsofatsa 'mele kapele ebile ha se lumelle ho nona ho feta tekano. Ka lebaka la sena, boima ba mokuli boa fokotseha 'me indices ea glycemic e thathamisitsoe. Meriana ea sehlopha sena e kenyelletsa tharollo bakeng sa ente ea Viktoz le Baeta, theko ea tsona e phahame haholo mme e fihla li-ruble tse 10,000.
Ho latela molao-motheo oa ts'ebetso, lithethefatsi li ka aroloa ka mefuta e meraro ea mantlha: lithethefatsi tse amang lihlekehleke tsa Langerhans le manyeme ho matlafatsa tšebeliso ea insulin, lithethefatsi tse eketsang phello ea lihormone tsoekere le lithethefatsi tse fokotsang tsoekere tse amang tekanyo ea ho monya tsoekere.
Kameho ho manyeme
Lithethefatsi tse amang manyeme e le ho ntlafatsa tlhahiso ea insulin li kenyeletsa Maninil, Diabeteson, Glyurenorm, Amaril.
Maninil o hlohlelletsa manyeme ho lokolla palo e phahameng ea lihormone tse hlokahalang e le hore tsoekere e kenang 'meleng ka lijo e monya ka potlako. Setlhare sena ka linako tse ling se baka karabelo e itseng, se tšoaetsanoang bakeng sa basali ba baimana, bana le bakuli ba nang le lefu la tsoekere la mofuta oa 1.
Diabeteson e sebetsa ka bonolo haholoanyane, e thusa ho sireletsa methapo ea mali le ho sebetsa mohato oa pele oa tlhahiso ea insulin. Moriana o na le litlamorao tse ngata ka tsela ea hlooho e bohloko, hypoglycemia, o fokotse nako ea ho tsepamisa maikutlo, o liehisa ho arabela, khatello ea maikutlo, tahlehelo ea boitšoaro. Setlhare sena se kopantsoe nakong ea kanyeso, ka mafu a sebete le a liphio.
- Glurenorm e laetsoe batho ba tsofetseng mme e ka nkeloa mafu a liphio. E thusa tlhahiso e sebetsang ea insulin. Phello e phahameng e etsahala hora kamora ho ja. Litlamorao tse ka bang teng ka mokhoa oa leukopenia, thrombocytopenia, hlooho, ho tsekela, ho otsela, mokhathala, ho se sebetse hantle ha pelo. Ka lefu la tsoekere la mofuta oa 1, lithethefatsi tsena li loantšitsoe.
- Amaryl ke mokhoa o sebetsang oa moloko oa ho qetela. Lithethefatsi li na le tšusumetso ea nako e telele 'me li thusa ho fokotsa kotsi ea hypoglycemia. Contraindication e kenyelletsa lefu la tsoekere la mofuta oa 1.
Ketso e ntlafalitsoeng ea insulin
Lithethefatsi tse ntlafatsang ketso ea lihormone li kenyelletsa Siofor le Metformin. Lithethefatsi tsena ha li ame makhopho, empa li eketsa tšebetso ea insulin, fokotsa ho monya tsoekere le mafura a tsoang ka mpeng. Thusa glucose ho kenella ka potlako.
Matlapa a Siofor a theola tsoekere e maling, a fokotsa boima ba 'mele' me a thusa ka botenya. Setlhare se kopantsoe le maoto a lefu la tsoekere, hypoglycemia, joala bo sa foleng, nakong ea kemolo. Matsatsing a pele a ho nka moriana, motho ea nang le lefu la tsoekere o utloa tatso ea tšepe ka molomong oa hae le bohloko ba ka mpeng.
Metformin e nkoa e le hypoglycemic e sebetsang; e nkoa hammoho le kalafo ea insulin.
Ho nwa moriana ho kopantsoe le ho hloleha ha sebete le lefu la tsoekere, lefu la tsoekere, ketoacidosis, ts'oaetso e matla, hypersensitivity, ho nyekeloa ke pelo, ho otloa ke pelo.
Matlafatso ea Glucose e ntlafalitsoeng
Ho theola mokhoa oa ho monya le ho fokotsa tsoekere ea mali, e thehiloeng ka lebaka la ho phatloha ha lijo, ngaka e fana ka taelo ea ho nka Acarbose le Glucobay. Matlapa ana a ka baka litlamorao tse fapaneng ka sebopeho sa dysbiosis, cholecystitis, ts'ebetso ea ho ruruha ka mpeng le mala.
Acarbose e na le phello ea hypoglycemic. Setlhare se kopantsoe le cirrhosis, ketoacidosis, methapo ea methapo ea litho tsa ka mpeng, ts'ebetso ea mokokotlo oa mokokotlo, nakong ea boimana le ho lactation. Litla-morao ka mokhoa oa lets'ollo le ho bata habonolo lia khoneha.
Glucobai e thusa ho fokotsa maemo a tsoekere ka mor'a ho ja, sethethefatsi se fanoa e le mokhoa o mong oa phepelo ea phepo e nepahetseng. Setlhare se ke ke sa nooa le mafu a ka mpeng, nakong ea kemaro le ho nyeka.
Ka linako tse ling motho ea tsoekere ea lefu la tsoekere a ka ba le ho hlasimoloha le bonolo ka mpeng.
Lithethefatsi tse ncha
Kajeno, inthanete e phatlalatsa ka ho hlaka lithethefatsi tse fapaneng tse ncha tse ntšang tsoekere ka har'a moroto. Lithethefatsi tse tsebahalang haholo ke moriana oa Farmiga oa lefu la tsoekere, Farsida, Forbinol.
Lithethefatsi tsena li na le litlhahlobo tse ngata tse ntle tse tsoang ho basebelisi. Leha ho le joalo, ho ea ka lingaka, ha ho hlokahale hore u lumele lithoriso tsena. Taba ke hore hajoale ha ho na lithethefatsi tse ka folisang ho hloka pancreatic ka botlalo.
Ntle le moo, mekhoa ea sejoale-joale e khothalletsoang e na le palo e kholo ea li-contraindication. Haholo-holo, tšebeliso ea lithethefatsi hangata e lebisa ho tšoaetsong ea pampiri ea urine, ka lebaka leo lefu la tsoekere le ka holisang ho hloloa ke lefu la mmele.
Lithethefatsi ha li na litaelo tse felletseng, e leng sesupo sa boleng bo bobe ba thepa. Ka litšenyehelo, meriana ena ha e khonehe ho batho ba bangata ba lefu la tsoekere.
Video e sehloohong sena e tla u bolella haholoanyane ka lithethefatsi tse theolelang tsoekere.
