Lefu la tsoekere la steroid ke eng: tlhaloso, matšoao, thibelo

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Steroidabetes mellitus e boetse e bitsoa lefu la tsoekere la lefu la tsoekere le amanang le lefu la tsoekere 1. Le hlaha ka lebaka la bongata bo feteletseng ba corticosteroids (lihormone tsa adrenal cortex) maling nako e telele.

Hoa etsahala hore lefu la tsoekere la steroid le hlaha ka lebaka la mathata a mafu moo ho nang le keketseho tlhahiso ea lihormone, mohlala, ka lefu la Itsenko-Cushing.

Leha ho le joalo, hangata lefu lena le hlaha kamora ho phekoloa ka nako e telele le lithethefatsi tse ling tsa lihormone, ka hona, le leng la mabitso a lefu lena ke lefu la tsoekere la lithethefatsi.

Mofuta oa lefu la tsoekere la tsoekere ka tlhaho ke karolo ea sehlopha sa mafu a tsoang kantle ho 'mele, qalong ha a amane le mathata a pancreatic.

Ho batho ba se nang mathata a amanang le metabolism ea carbohydrate haeba ho na le li-glucocorticoids tse ngata, e etsahala ka mokhoa o bonolo ebe makhasi kamora hore a hlakoloe. Hoo e ka bang 60% ea batho ba kulang, lefu la tsoekere la 2 le baka phetoho ea mofuta o ikemetseng oa lefu lena ho ea itšetlehileng ka insulin.

Mekhoa ea meriana ea lefu la tsoekere

Lithethefatsi tsa Glucocorticoid, tse kang dexamethasone, prednisone le hydrocortisone, li sebelisoa e le lithethefatsi tse khahlanong le ho fokola bakeng sa:

  1. Lerotholi la bronchial;
  2. Rheumatoid ramatiki;
  3. Maloetse a Autoimmune: pemphigus, eczema, lupus erythematosus.
  4. Multiple Sclerosis.

Lefu la tsoekere la meriana le ka hlaha ka tšebeliso ea li-diuretics:

  • thiazide diuretics: dichlothiazide, hypothiazide, nephrix, Navidrex;
  • lipilisi tsa thibelo ea bokhachane.

Methapo e meholo ea li-corticosteroids e boetse e sebelisoa e le karolo ea kalafo e khahlanong le ho ruruha kamora ho ts'ebetsoa ha mothofatso oa meno.

Kamora ho fetisoa, bakuli ba lokela ho nka chelete ho hatella boits'ireletso ba bophelo bohle. Batho ba joalo ba tloaetse ho tsoaetso, eo, qalong, e sokelang setho se fetisitsoeng hantle.

Lefu la tsoekere la moriana ha le thehoe ho bakuli bohle, leha ho le joalo, ka mokokotlo o sa feleng oa lihormone, monyetla oa ho hlaha ha lona o phahame ho feta ha ba phekola mafu a mang.

Matšoao a lefu la tsoekere a bakoang ke li-steroid a bontša hore batho ba kotsing.

E le hore ba se ke ba kula, batho ba mafura ba lokela ho theola boima ba 'mele; ba nang le boima bo tloaelehileng ba hloka ho ikoetlisa, 'me ba etse liphetoho lijong tsa bona.

Ha motho a tseba hore o na le lefu la tsoekere, ho hang ha ua lokela ho nka meriana ea lihormone ho latela maikutlo a hau.

Likarolo tsa lefu lena le matšoao

Lefu la tsoekere la Steroid le khethehile ka hore le kopanya matšoao a lefu la tsoekere la mofuta oa bobeli le lefu la tsoekere la 1. Lefu lena le qala ha palo e kholo ea li-corticosteroids e qala ho senya lisele tsa pancreatic beta.

Sena se tsamaisana le matšoao a lefu la tsoekere la mofuta oa 1. Leha ho le joalo, lisele tsa beta li ntse li tsoela pele ho hlahisa insulin ka nako e telele.

Hamorao, bophahamo ba insulin boa fokotseha, kutloisiso ea mesifa ea hormone ena le eona ea ferekanngoa, e etsahalang ka lefu la tsoekere 2.

Kamora nako, lisele tsa beta kapa tse ling tsa tsona lia senyeha, e lebisang ho emeng tlhahiso ea insulin. Kahoo, lefu lena le qala ho tsoela pele ka mokhoa o ts'oanang le lefu la tsoekere le tloaelehileng le thehiloeng ho insulin 1. Ho bonts'a matšoao a tšoanang.

Matšoao a bohlokoa a lefu la tsoekere le lefu la tsoekere a tšoana le mofuta ofe kapa ofe oa lefu la tsoekere:

  1. Ho eketsa urination;
  2. Nyoriloe;
  3. Mokhathala

Ka tloaelo, matšoao a thathamisitsoeng ha a bonts'e haholo, ka hona ha a elloe hloko hangata. Bakuli ha ba fokotse boima ba 'mele haholo, joalo ka lefu la tsoekere la mofuta oa 1, liteko tsa mali ha se kamehla li etsang hore ho be le tlhahlobo ea mali.

Keketseho ea tsoekere maling le morong e phahame ka mokhoa o sa tloaelehang. Ntle le moo, boteng ba lipalo tsa acetone e maling kapa moroto ha bo bonoe hangata.

Lefu la tsoekere e le sesosa sa kotsi ea lefu la tsoekere la steroid

Palo ea li-hormone tsa adrenal e eketseha ho batho bohle ka litsela tse fapaneng. Leha ho le joalo, ha se batho bohle ba nkang glucocorticoids ba nang le lefu la tsoekere la steroid.

Taba ke hore ka lehlakoreng le leng, corticosteroids e sebetsa ho manyeme, 'me ka lehlakoreng le leng, e fokotsa phello ea insulin. E le hore khatello ea tsoekere ea mali e lule e tloaelehile, manyeme a qobelloa ho sebetsa ka mojaro o boima.

Haeba motho a e-na le lefu la tsoekere, joale maikutlo a lisele tsa ho kenella ho insulin a se a fokotsehile, mme gland ha e na 100% ho sebetsana le mesebetsi ea eona. Phekolo ea steroid e lokela ho etsoa feela joalo ka khetho ea ho qetela. Kotsi e eketseha ka:

  • tšebeliso ea li-steroid maemong a phahameng;
  • tšebeliso ea nako e telele ea li-steroid;
  • mokuli ea boima bo feteletseng.

Ho lokela ho ba hlokolosi ha ba etsa liqeto le bao ka linako tse ling ba nang le tsoekere e phahameng ea mali ka mabaka a sa hlalosoang.

Ho sebelisa li-glucocorticoids, lipontšo tsa lefu la tsoekere lia eketseha, 'me sena se makatsa motho, hobane o ne a ka se tsebe ka lefu la hae la tsoekere.

Tabeng ena, lefu la tsoekere le ne le le bobebe pele ho nkeloa li-glucocorticoids, ho bolelang hore lithethefatsi tse joalo tsa lihormone li tla mpefatsa boemo mme li ka baka boemo bo kang ho ba le lefu la tsoekere.

Pele o fana ka lithethefatsi tsa lihormone, batho ba baholo le basali ba fetang boima ba mmele ba hloka ho hlahlojoa lefu la tsoekere la morao.

Phekolo ea lefu la tsoekere

Haeba 'mele o se o sa hlahise insulin, joale lefu la tsoekere la lithethefatsi, joalo ka lefu la tsoekere la mofuta oa 1, empa le na le likarolo tsa lefu la tsoekere la mofuta oa 2, ka mantsoe a mang, ho hanyetsoa ha insulin. Lefu la tsoekere le tšoaroa joalo ka lefu la tsoekere 2.

Phekolo, ho fapana le lintho tse ling, ho latela hantle hore na mokuli o na le mathata afe. Mohlala ho batho ba nonneng haholo ba ntseng ba hlahisa insulin, ho hlahisoa lijo le lithethefatsi tse fokotsang tsoekere tse kang thiazolidinedione le glucophage. Ntle le moo:

  1. Haeba ho na le ts'ebetso ea pancreatic e fokotsehileng, joale ho kenngoa ha insulin ho tla e nolofalletsa ho fokotsa mojaro.
  2. Tabeng ea atrophy e sa phethahalang ea lisele tsa beta, ha nako e ntse e tsamaea, ts'ebetso ea pancreatic e qala ho fola.
  3. Bakeng sa morero o ts'oanang, ho fanoa ka lijo tsa carb tse tlase.
  4. Bakeng sa batho ba nang le boima bo tloaelehileng, ho khothalletsoa ho ja ja 9;

Haeba manyeme a sa hlahise insulin, joale e laetsoe ka ente mme mokuli o tla hloka ho tseba ho kenya insulin hantle. Taolo ea tsoekere ea mali le kalafo li etsoa ka mokhoa o tšoanang le lefu la tsoekere 1. Ho feta moo, lisele tse shoeleng tsa beta li ke ke tsa khutlisoa.

Nyeoe e arohaneng ea kalafo ea lefu la tsoekere e khothalletsoang ke lithethefatsi ke boemo boo ho ke keng ha khoneha ho hana phekolo ea li-hormone, empa motho o fetoha lefu la tsoekere. Sena e ka ba kamora ho fetisoa ha meno kapa ho na le asthma e matla.

Tekanyo ea tsoekere e bolokoa mona, e ipapisitse le polokeho ea manyeme le boemo ba linama tse hlasetsoeng ke insulin.

Ha e le tšehetso e eketsehileng, bakuli ba ka fuoa lihormone tsa anabolic tse lekanyang litlamorao tsa lihormone tsa glucocorticoid.

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