Ho tseba lefu la tsoekere ho hloka mafu a mangata. Mokuli o fuoa tlhahlobo ea mali le a moroto bakeng sa tsoekere, tlhahlobo ea khatello ea kelello le tsoekere.
Ho lefu la tsoekere mellitus, boikemisetso ba C-peptide maling bo tlameha.
Sephetho sa tlhahlobo ena se tla bonts'a hore na hyperglycemia ke phello ea khaello ea insulin e felletseng kapa e amanang. Ke eng e sokelang ho fokotseha kapa keketseho ea C-peptide, re tla e sekaseka ka tlase.
C peptide ke eng?
Ho na le tlhahlobo e ka lekolang mosebetsi oa lihlekehleke tsa Langerhans ka har'a manyeme le ho senola boholo ba secretion ea hormone ea hypoglycemic 'meleng. Letšoao lena le bitsoa peptide e hokahanyang kapa C-peptide (C-peptide).
Makhopho ke mofuta oa polokelo ea lihormone tsa protheine. E bolokiloe ka mokhoa oa proinsulin. Ha motho a phahamisa tsoekere, proinsulin e putlama ka peptide le insulin.
Ho motho ea phetseng hantle, karo-karolelano ea bona e lokela ho lula e le 5: 1. Boikemisetso ba C-peptide bo senola ho fokotseha kapa keketseho ea tlhahiso ea insulin. Ketsahalong ea pele, ngaka e ka hlahloba lefu la tsoekere, mme ho bobeli, ea insulin.
Tlhatlhobo e behiloe tlasa maemo afe le maloetse?
Mafu ao ho a hlahlobeloang litlhaloso:
- mofuta oa 1 le mofuta oa 2 lefu la tsoekere;
- mafu a fapaneng a sebete;
- ovary ea polycystic;
- makhopho a pancreatic;
- ho buuoa ka pancreatic;
- Cushing's syndrome;
- hlokomela kalafo ea li-hormone bakeng sa lefu la tsoekere la mofuta oa 2.
Insulin e bohlokoa ho batho. Ena ke eona hormone ea bohlokoa e amehang ho metabolism ea carbohydrate le tlhahiso ea matla. Tlhahlobo e khethollang boemo ba insulin maling ha e ea nepahala kamehla.
Mabaka a tjena:
- Pele, insulin e thehoa makhophong. Ha motho a phahamisa tsoekere, lihormone li kena pele ho sebete. Moo, karolo e itseng ea lula, 'me karolo e' ngoe e etsa ts'ebetso ea eona mme e fokotsa tsoekere. Ka hona, ha u lekola boemo ba insulin, boemo bona bo tla lula bo le tlase ho feta li-pancreas tse kopantsoeng.
- Kaha tlhahiso e ka sehloohong ea insulin e etsahala ka mor'a ho ja lik'habohaedreite, boemo ba eona bo nyoloha ka mor'a ho ja.
- Lintlha tse sa nepahalang li fumanoa haeba mokuli a e-na le lefu la tsoekere 'me a phekoloa ka insulin hape.
Ka lehlakoreng le leng, C-peptide ha e lule kae kapa kae 'me e kena mohloling oa mali hanghang, ka hona thuto ena e tla bonts'a linomoro tsa' nete le palo e nepahetseng ea li-hormone tse hlahisitsoeng ke manyeme. Ntle le moo, k'hemik'hale ha e kopantsoe le lihlahisoa tse nang le tsoekere, ke hore, boemo ba eona ha bo eketsehe kamora ho ja.
Ts'ebetso e etsoa joang?
Lijo tsa mantsiboea tse 8 pele u nka mali li lokela ho ba bobebe, li se na lijo tse mafura.
Algorithm ea ho etsa lipatlisiso:
- Mokuli o tla ka mpeng e se nang letho ka phapusing ea pokello ea mali.
- Mooki o nka mali a venous ho eena.
- Madi a tšeloa ka har'a mothapo o khethehileng. Ka linako tse ling e na le gel e khethehileng e le hore mali a se ke a baka.
- Ebe tube e kenngoa ka centrifuge. Sena sea hlokahala e le hore o ka arola plasma.
- Ebe mali a tšeloa ka sehatsetsing 'me a fokotsoe ho likhato tse 20.
- Kamora moo, tekanyo ea peptide ea "insulin" maling e ikemiselitse.
Haeba mokuli a belaelloa ka lefu la tsoekere, o fuoa tlhahlobo ea khatello ea maikutlo. E na le ts'ebetsong ea glucagon e kenang kapa ho kenella ha tsoekere. Ebe ho na le tekanyo ea tsoekere ea mali.
Seo se ama litholoana life?
Boithuto bo bontša manyeme, ka hona molao o ka sehloohong ke ho boloka lijo.
Khothaletso ea mantlha ea bakuli ba nyehelang mali ho C-peptide:
- Lihora tse 8 ka potlako pele ho monehelo oa mali;
- o ka nwa metsi a a senang khabone;
- o ka se noe joala matsatsi a 'maloa pele ho thuto;
- Fokotsa khatello ea maikutlo 'meleng le maikutlong;
- u seke oa tsuba lihora tse 3 pele thuto e fela.
Tloaelo ho banna le basali e tšoana ebile e tloha ho 0.9 ho isa ho 7, 1 μg / L. Liphetho li ikemetse ka lilemo le bong. Re lokela ho hopola hore libakeng tsa mahlale tse fapaneng litholoana tsa maemo li ka fapana, ka hona, boleng ba litšupiso bo lokela ho ananeloa. Lits'ebetso tsena ke kakaretso ea laboratori ena mme e thehiloe kamora tlhahlobo ea batho ba phetseng hantle.
Puo ea video ka lisosa tsa lefu la tsoekere:
Ke maemong afe moo boemo bo ka tlase bo tloaelehileng?
Haeba boemo ba peptide bo le tlase, 'me tsoekere, ho fapana le hoo, e phahame, ena ke pontšo ea lefu la tsoekere. Haeba mokuli a le monyane 'me a sa motenya, ho ka etsahala hore a tšoaroe ke lefu la tsoekere la mofuta oa 1. Bakuli ba tsofetseng ba nang le tloaelo ea botenya ba tla ba le lefu la tsoekere la 2 le nete hore Maemong ana, mokuli o lokela ho bontšoa liente tsa insulin. Ntle le moo, mokuli o hloka tlhahlobo e eketsehileng.
O abetsoe:
- tlhatlhobo ea fundus;
- boikemisetso ba boemo ba likepe le methapo ea lipheo tse tlase;
- qeto ea mesebetsi ea sebete le ea liphio.
Litho tsena ke "liphofu" 'me li utloa bohloko bo boholo ba tsoekere e maling. Haeba kamora ho hlahloba mokuli o na le mathata le litho tsena, joale o hloka ho khutlisetsoa ka potlako boemo ba glucose bo tloaelehileng le kalafo e eketsehileng ea litho tse amehang.
Phokotso ea peptide le eona e etsahala:
- kamora ho tlosoa ha karolo ea manyeme;
- hypoglycemia ea maiketsetso, ke hore, ho fokotseha ha tsoekere ea mali ho ileng ha bakoa ke liente tsa insulin.
Ke maemong afe moo boemo bo kaholimo ho bo tloaelehileng?
Liphetho tsa tlhahlobo e le 'ngoe li ke ke tsa lekana, ka hona mokuli o fuoa bonyane tlhahlobo e le' ngoe ho bona hore na tsoekere e maling e kae.
Haeba C-peptide e phahame 'me ho se na tsoekere, joale mokuli o fumanoa a e-na le insulin kapa prediabetes.
Maemong ana, mokuli ha a hloke ho entoa insulin, empa o hloka ho potlakisa ho fetola mokhoa oa hae oa bophelo. Qoba mekhoa e mebe, qala ho bapala lipapali 'me u je ka nepo.
Mehato e phahamisitsoeng ea C-peptide le glucose li bontša boteng ba lefu la tsoekere la mofuta oa 2. Ho latela boima ba lefu lena, ho ka fuoe motho matlapa kapa liente tsa insulin. Hormone e fuoa ts'ebetso ea nako e telele, makhetlo a 1 - 2 ka letsatsi. Haeba litlhoko tsohle li bonoa, mokuli a ka qoba liente mme a lula litafoleng feela.
Ntle le moo, keketseho ea C-peptide e ka etsahala ka:
- insulinoma - hlahala ea pancreatic e kopanyang insulin e ngata;
- ho hanyetsa insulin - boemo boo ho bona litho tsa motho li lahleheloang ke kutloisiso ea tsona ea insulin;
- lefu la polycystic ovary - lefu la basali le tsamaeang le mathata a lihormone;
- ho se sebetse hantle ha renal - mohlomong e le ntho e patiloeng ea lefu la tsoekere.
Boikemisetso ba C-peptide maling ke tlhahlobo ea bohlokoa ho hlokeng lefu la tsoekere le lefu la tsoekere le mekhoa e meng ea lefu lena. Ho tseba ka nako le kalafo ea lefu lena le qalile ho tla thusa ho boloka bophelo bo botle le ho lelefatsa bophelo.
