Ho senyeha ha potoloho ea mali bokong, litlamorao tse mpe tsa chefo le ho fokotseha ha molumo oa methapo ho lebisa ponahalong ea maloetse a matla a methapo ea pelo, ea pelo le a mang. Ho thibela nts'etsopele ea hypoxia le lefu la lisele tsa boko, bakuli ba fuoa li-antioxidants, metabolism, antihypoxants, nootropics le lithethefatsi tse ling tsa neurotropic.
Ho latela sebaka sa lesapo, kalafo ea mafu a ischemic le methapo ea methapo, ho sebelisoa li-agents tse kang Mildronate le Mexidol.
Litšoaneleho tse akaretsang tsa lithethefatsi
Mexidol le Mildronate li abetsoe:
- metabolism e ntlafalitsoeng;
- ts'ebetso ea ho potoloha ha mali methapong ea bokong;
- eketsa ho hanyetsa khatello ea maikutlo le kelello.
Ha ho phekoloa mafu a ischemic le pathologies ea methapo, Mildronate le Mexicoidol li sebelisoa.
Matšoao a mang a ts'ebeliso ea lichelete tsena a hlahisoa ke ts'ebetso ea ts'ebetso ea likarolo tse sebetsang.
Mexicoidol
Motsoako o sebetsang oa Mexicoidol ke ethylmethylhydroxypyridine succinate. Ntho ena ke lintho tse hlahisang acid e tsoakiloeng, e kopanyang thepa ea mosireletsi oa membrane, antioxidant le metabolism ea "metabolic".
Letsoai la Succinic acid le thibela ho haella ha mafura a mangata, le ho fokotsa tlhokahalo ea oksijene liseleng tsa boko le ho eketsa ho hanyetsa ha tsona ho hypoxia. Mexicoid activates ts'ebetso ea matla ea mitochondria mme e tsitsisa boemo ba likhomphutha tsa macroergic (ATP, jj.).
Mexidol e hlohlelletsa ho kenella ka hare ho acid ea li-nucleic acid le ho tsosolosoa ha li-membrane tsa lisele, ho kenya ts'ebetsong oxidation ea tsoekere.
Setlhare se tsosa ho kenella kahare ho acid ea acid le ho khutlisetsa li-membrane tsa sele, se sebetsisang oxidation ea tsoekere le ho ntlafatsa phetiso ea synaptic lipakeng tsa likarolo tsa bokong. Tšusumetso e ntle litekanyetsong tsa mali tsa rheological le boemo ba lipoprotein tse tlase-tlase li ka fokotsa sebaka sa tšenyo e ke keng ea fetoloa ho ischemia le ho thibela vasen stenosis nakong e tlang.
Tšebeliso ea Mexicoidol bakeng sa ho khaotsa ho thusa ho tsitsisa mokuli kapele le ho fokotsa litakatso tsa joala.
Morero oa lithethefatsi o bontšoa li-pathologies tse latelang:
- encephalopathy ea discirculatory, post-traumatic le genesis tse ling, ho kenyeletsoa e tsamaeang le litlhaselo tse tšosang;
- limela-vascular dystonia, asthenia;
- litlamorao tsa likotsi tsa cerebrovascular, TIA, likotsi tse mpe tsa boko;
- ho senyeha hoa kelello ha atherosulinotic etiology (ka lefu le bonolo la methapo);
- IHD (e le karolo ea thupelo e felletseng);
- mathata a ho tšoenyeha a nang le maloetse a amanang le neurosis le neurosis;
- ho tahoa le lithethefatsi tse thibelang kelello ho hlasela, matšoao a ho khaotsa ho ts'epa joala (a na le matšoao a kang a limela le methapo);
- khatello ea maikutlo, ho ikitlaetsa 'mele haholo (ho hanyetsa khatello ea maikutlo le ho thibela nts'etsopele ea maloetse a systemic).
Setlhare se fumaneha ka mokhoa oa matlapa le tharollo ea infusion.
Contraindication mabapi le ts'ebeliso ea Mexicoidol ke:
- kutloisiso ea motho ka mong litokisong tsa acid ea presinic;
- ho hloleha ho matla ha tšebetso ea liphio le sebete;
- lebone
- boimana
- lilemo tsa bana.
Mildronate
Ntho e sebetsang ea Mildronate ke meldonium. Mosebetsi oa mantlha oa karolo ena, hammoho le analogue ea eona ea sebopeho (gamma-butyrobetaine), e fumanehang ka seleng e 'ngoe le e' ngoe ea 'mele oa motho, ke ho fokotsa moelelo oa carnitine. Ka ho fokotseha ha tlhahiso ea carnitine, matla a ho tsamaisa mafura acid ho lisele a fokotseha, mme mohloli o ka sehloohong oa matla bakeng sa li-tishu tsa mmele (ATP) o qala ho hlahisoa haholo-holo ka lebaka la glucose, oxidation ea eona e hlokang oksijene e nyane mme e sa tlohele palo e kholo ea lihlahisoa tse nang le chefo.
Ho fetola mofuta oa lits'ebetso tsa metabolic ho fokotsa tlhoko ea oksijene ea li-tishu, ho fokotsa hypoxia, mme ho thibela ts'enyo ea lisele ka lihlahisoa tse chefo tse amanang le metabolism.
Analog ea maiketsetso ea gamma-butyrobetaine e boetse e na le thepa ea vasodilating (vasodilating), e thusang ho ntlafatsa phallo ea mali, e liehise ho theha libaka tsa necrosis nakong ea ho hlaseloa ke pelo le stroke. Ho abeloa mali hape molemong oa libaka tsa ischemic ho fokotsa kotsi ea ho hloka taolo ea trophic, ho fokotsa botebo ba syndrome ea bohloko, ho eketsa mamello ea mmele le ts'ebetso.
Mildronate e fokotsa tlhoko ea oksijene ea lithane ka ho fokotsa hypoxia hape e thibela tšenyo ea lisele chefo.
Ts'ebeliso ea meldonium e boetse e khothaletsoa bakeng sa matšoao a bang teng: setlhare se fokotsa matšoao a botahoa, se emisa ts'ebetso ea ts'ebetso ea methapo ea methapo mme e thusa matšoao a ho khaotsa ho phekola joala bo sa foleng.
Matšoao a ts'ebeliso ea Mildronate ke mekhoa e latelang:
- lefu la pelo le methapo, le tsamaeang le ho opeloa ke sefuba;
- myocardial infarction;
- ho senyeha ha litho tsa mesifa ea pelo le ho nyekeloa ke pelo;
- mathata a ho potoloha ha lesapo la mokokotlo (mokokotlo oa mokokotlo, boemo ba pele ho stroke);
- thrombosis ea mefuta e fapaneng;
- ho tsoa mali ho leihlo la mahlo le retina, ho phatloha ha methapo e ka sehloohong ea mokokotlo le makala a eona, retinopathy;
- discirculatory encephalopathy, neuropathy le liso tse ling tsa lefu la tsoekere, phaello e potlakileng ea boima ba mofuta oa 2 lefu la tsoekere;
- syndrome ea ho ntša maikutlo;
- maemo a tlase a ho sebetsa;
- khatello ea maikutlo, ho ikoetlisa ka matla.
Boithuto bo bongata bo bonts'a katleho ea Mildronate kalafong e rarahaneng ea lefu le ruruhileng la pulmonary.
Ho latela lipontšo, e 'ngoe ea mefuta e meraro ea ho lokolloa ha moriana e sebelisoa:
- lipilisi;
- sirapo;
- tharollo bakeng sa parabulbar (intraocular) le tsamaiso ea methapo.
Contraindication ho kalafo le Mildronate:
- maikutlo a motho ka mong ka likarolo tsa moriana;
- khatello e phahameng ea kelello e kenang ka hare (e nang le liqhubu le ho ruruha ho hoholo ha venous);
- boimana
- lebone
- lilemo tsa bana.
Ka methapo e matla ea liphio le sebete, kalafo e lokela ho etsoa ka hloko.
Papiso ea Mexicoidol le Mildronate
Mildronate le Mexicoidol li sebelisoa bakeng sa matšoao a tšoanang mme li na le phello e ts'oanang ea antihypoxic, e khethollang ts'ebetso ea bona ho ischemia ea libaka tsa boko. Leha ho tšoana, lithethefatsi tsena ha li na likarolo tse tloaelehileng ebile li fapana ka ts'ebetso e fapaneng.
E tšoanang
Lithethefatsi ka bobeli li fokotsa tlhoko ea oksijene bokong le liseleng tsa mesifa ea pelo ka ho emisa karabelo ea peroxidation (maemong a Mexicoidol) kapa ka ho thibela ho tsamaisoa ha mafura acid (maemong a Mildronate). Sena se o lumella ho fokotsa sebaka sa necrosis ka ho otloa le ho otloa ke pelo, hammoho le ho eketsa mamello ea mojaro o boima.
Ho ntlafatsa phallo ea mali nakong ea kalafo le Mexicoidol kapa Mildronate ho na le phello e molemo ho bakuli ba kileng ba otloa ke stroke kapa ba nang le matšoao a ho khaoha.
Ho sebelisana ha lithethefatsi ho ntlafatsa phello ea kalafo. Ka lefu la ischemic, matšoao a vestibulo-ataxic disorder, arrhythmias, matšoao a ho khaotsa le li-pathologies tse ling, Mildronate le Mexicoidol li ka nkoa ka nako e le ngoe.
Mildronate le Mexicoidol li hanyetsanoa nakong ea kemaro le ho lactation.
Phapang ke efe?
Phapang lipakeng tsa lithethefatsi tsena tse peli e ka tsela e fapaneng le ea tlhaiso-leseling. Mexidol e na le phello ea ho thusa ho hlophisa lintho hantle, ho hlapanya kelello, ho hlahisa kholofalo, antioxidant le moferefere o fokolang oa ho tšoenyeha, 'me Mildronate o na le phello ea angio-le pelo.
Ka kalafo ea Mexicoidol, ketsahalo ea:
- molomo o omileng
- ho nyekeloa
- karabelo ea mmele o mong le o mong;
- ho otsela.
Litla-morao tsa Mildronate ke:
- dyspepsia
- sekhahla sa pelo;
- khatello ea khatello;
- ho se khonehe.
Maemong a sa tloaelehang, bofokoli, maikutlo a ho kula, le ho eketseha ha khatello ea eosinophils li bonoa.
Lithethefatsi ka bobeli li loantsoe bongoaneng.
E leng theko e tlase
Litšenyehelo tsa Mexicoidol li tsoa ho li-ruble tse 274 bakeng sa matlapa a 30 (litekanyetso - 125 mg) le li-ruble tse 1423 bakeng sa li-ampoules tse 20 tsa 5 ml (litekanyetso - 50 mg / ml).
Theko ea Mildronate e qala ho tloha ho li-ruble tse 255 bakeng sa li-capsule tse 40 (litekanyetso - 250 mg) le ho tloha ho li-ruble tse 355 bakeng sa li-ampoules tse 10 tsa 5 ml (dosage - 100 mg / ml).
Ha u fuoa lethal dose e khothalletsoang ea kalafo (400-800 mg / letsatsi bakeng sa Mexicoidol le 500-1000 mg / letsatsi bakeng sa Mildronate), kalafo ea meldonium e nang le matšoao a tšoanang e tla bitsa theko e tlase haholo.
E leng molemo: Mexicoidol kapa Mildronate
Mexidol ke sethethefatsi sa nootropic le antioxidant, se hangata se laeloang bakeng sa mathata a phepelo ea mali ho lithane tsa boko le liso tsa methapo ea methapo ea methapo ea methapo. Mildronate e na le phello e kholo lits'ebetsong tsa metabolic liseleng le boemo ba tsamaiso ea methapo ea pelo.
Khetho ea chelete ke boikarabello ba ngaka e eang ho ngaka (ngaka ea methapo, ngaka ea methapo, narcologist). Ha a fana ka moriana, o nahana ka lipontšo le nalane ea mokuli.
Tlhahlobo ea lingaka
Poroshnichenko A.I., setsebi sa methapo, Ryazan
Mexicoidol ke lithethefatsi tse sebetsang le tse theko e tlaase tsa moetsi oa lapeng, tse laetsoeng li-pathologies tse ngata tsa methapo. E mamelloa haholo ke bakuli ebile ha e hlabe e hlekefetsa maikutlo a fapaneng.
Bothata ba sethethefatsi ke katleho e tlase ea sebopeho sa eona sa molomo (matlapa). Ho fihlella sephetho kapele, Mexicoidol e lokela ho nkuoa ka methapo kapa kahare.
Mayakov A.I., narcologist, Kursk
Mildronate e felisa lipontšo tse tloaelehileng tsa asthenic, e khutsufatsa nako ea ntlafatso bakeng sa joala bo sa foleng, mme e felisa ho tsitsipana ha trophic ho likhoele tsa methapo ea methapo ho mafu a kang lefu la tsoekere. Setlhare se na le litla-morao tse sebetsang tsa antiarrhythmic ebile se fokotsa nako ea ketso ea lithethefatsi tse ling tsa kelello.
Minus Mildronate ke litla-morao (bofokoli, allergies, liphetoho khatello ea mali), leha ho le joalo, lia fumaneha.
Ho nka tekanyetso e khothalletsoang, kalafo ea meldonium e nang le matšoao a tšoanang e tla bitsa theko e tlase haholo.
Maikutlo a bakuli mabapi le Mexicoidol le Mildronate
Ekaterina, ea lilemo tse 41, Moscow
Kamora ho etsoa opereishene mokokotlong (lefu leo ke letsoele la lesapo la mokokotlo), bohloko bo ile ba hlaha litempeleng le mokokotlong oa hlooho. Ke qetile matsatsi a 'maloa ke noella likokoana-hloko, empa leha ho le joalo ke ile ka retelehela ho ngaka ea methapo. Ngaka e ile ea fana ka thupelo ea ente ea 10 ea Mexicoidol. Ka letsatsi la 4, ke ile ka utloa ntlafatso ea pele, ka la 6, bohloko bo ile ba fela ka botlalo.
Kamora phekolo, o hlokometse hore o qalile ho robala hamolemo, a arabela ka mokhoa o khutsitseng le o kopaneng likhatellong le likhohlano, mme o tsepamisa maikutlo haholo mosebetsing. Ha kea ka ka hlokomela litla-morao leha e le life, ke khotsofetse ke sethethefatsi sena.
Maria, ea lilemo li 33, Tomsk
Ke kentse Mildronate matsatsi a 10 ka khothatso ea ngaka. Matsatsing a pele, phello ha e bonahale, empa kamora 'nete e felletseng khatello e khutletse ho tloaelehileng, lerata hloohong, ho hloka boroko le mokhathala o sa feleng li ile tsa fela. Hona joale ke se ke le mafolofolo mosebetsing ebile ke ipha nako ea ho etsa lintho tseo ke li ratang haholo.
Liente ke mokhoa o sa thabiseng, empa phello ea tsona ea hlolla.
