K'holeseterole e phahameng hangata e hlaha khahlano le semelo sa nts'etsopele ea pathologies le phepo e fosahetseng. Keketseho ea palo ea potoloho e ka lebisa ho angina pectoris, lefu la pelo, le maemo a mang a kotsi. Atorvastatin 20 e tla thusa ho inalosa cholesterol ea mali.
Lebitso la Machaba le sa Tšoanelehang
Lithethefatsi tsa INN - Atorvastatin (Atorvastatin).
Atorvastatin 20 e tla thusa ho inalosa cholesterol ea mali.
ATX
Khoutu ea ATX ke C10AA05.
Lokolla liforomo le sebopeho
Ho lokolloa ha moriana ho ka tsela ea matlapa. Atorvastatin khalsiamo ea calcium ke ntho e sebetsang e teng ka tekanyo ea 20 mg.
Likarolo tse ling tse nang le boleng bo thusang ke:
- aerosil;
- calcium carbonate;
- MCC;
- lactose;
- starch;
- magnesium stearate;
- mahlohonolo.
Ho lokolloa ha moriana ho ka tsela ea matlapa.
Ketso ea pharmacological
Motsoako oa litlhare ke setlhare se fokolisang lipid se amanang le li-statins. Setlhare sena se ikemiselitse ho hlahisa enzyme eo e leng thibelo ea Phokotso ea HMG-CoA. Enzyme ena e lebisa liketsong tse fokotsang khoholeho ea cholesterol e felletseng le ho potlakisa matla a cholesterol ea LDL.
Ntle le moo, sesebelisoa se na le phello e ntle ho boteng ba mali le marako a lijana. Mefuta e meng ea lithethefatsi ke antiproliferative le antioxidant.
Bala hape papiso ea lithethefatsi le ba bang:
Atorvastin kapa Atoris? - ho feta sengoliloeng sena.
Atorvastin kapa Simvastin: ke eng e betere?
Rosuvastine kapa Atorvastine?
Mofumahali
Litšobotsi tsa Pharmacokinetic li na le likarolo tse latelang:
- ho felisoa ha halofo ea bophelo ba teng lihora tse ka bang 14;
- bioavailability e tlase;
- metabolism ka har'a sebete, e tsamaisana le ho thehoa ha lintho tse sa sebetseng le metabolites;
- tlama ho liprotheine tsa mali - 98%;
- ho monya haholo;
- ho fihlela tlhoro ea mahloriso a plasma kamora lihora tse 1-2.
Lithethefatsi li tšeloa ka har'a sebete.
Ba abetsoe eng?
Ho latela litaelo tsa tšebeliso, matšoao a ho nka meriana ke:
- dysbetalipoproteinemia;
- Hyperlipidemia e tsoakiloeng;
- heterozygous hypercholesterolemia ea lelapa le e seng ea lelapa;
- endo native hypertriglyceridemia;
- homozygous Familyal hypercholesterolemia;
- tlhokeho ea ho theola boemo ba apoliprotein, triglycerides le cholesterol e felletseng hammoho le lijo tse fokotsang lipid.
Contraindication
Setlhare ha se khothalletsoe ha mokuli a e-na le litlolo tse joalo:
- ho se mamelle lintho tse etsang Atorvastatin;
- metabolism ea sebete karolong e sebetsang;
- li-enzyme tse phahameng tsa sebete, sesosa sa tsona li neng li sa fumanehe;
- ho hloleha ha sebete.
Setlhare ha se khothalletsoe ha mokuli a e-na le lefu la sebete karolong e sebetsang.
Ka tlhokomelo
Sebelisa moriana ka hloko ha o na le li-pathologies le maemo a bonts'itsoeng:
- khatello ea kelello ea methapo;
- tlhaho e sa laoleheng ea sethoathoa;
- ho ba teng nalaneng ea mokuli ea mafu a sebete;
- sepsis;
- mathata a endocrine le metabolic;
- likotsi
- marapo a marapo a marapo;
- ho leka-lekana ho matla ha electrolyte;
- bokhoba ba joala.
U ka nka atorvastatin 20 joang?
Pele a qala kalafo, mokuli o tlameha ho latela lijo tse fokotsang lipid. Melao e tšoanang ea phepo e nepahetseng e tla hloka ho bonoa nakong ea kalafo le Atorvastatin.
Sesebelisoa se ka sebelisoa ka nako efe kapa efe ea letsatsi.
Tekanyetso ha ea itšetleha ka tšebeliso ea lijo. Palo ea meriana e khethoa ka bonngoe, hobane hoa hlokahala ho ela hloko lipheo tsa kalafo, litšobotsi tsa 'mele oa mokuli, boemo ba lipoprotein tse fokolang le cholesterol.
Tekanyetso ha ea itšetleha ka tšebeliso ea lijo.
Ho nka moriana oa lefu la tsoekere
Nakong ea lefu la tsoekere, moriana o nooa ho latela litaelo le litlhahiso tsa setsebi.
Litlamorao
Phekolo ea ka mpeng
Tšebeliso ea lithethefatsi e ka lebisa lipontšong tse latelang:
- belching;
- ho tsoa mali ka mokokotlo;
- botumo;
- phetoho ea takatso ea lijo ka thoko ea ho eketseha kapa ho mpefala;
- ho nyekeloa
- bohloko bo ka mpeng;
- molomo o omileng
- lets'ollo
- setuloana se ntšo;
- seso sa ka mpeng;
- mathata a ka har'a sebete;
- tšenyo ea kolon le mala;
- boemong bo sa thabiseng ho rectum.
Tsamaiso ea methapo e bohareng
Litla-morao li ka hlaha ka lehlakoreng la tsamaiso ea methapo e kholo, ka lebaka leo ho tla ba le lipontšo:
- ho otsela
- ho holofala sefahlehong;
- Ho sithabela maikutlo
- ho felloa ke letsoalo;
- litoro tse mpe;
- hlooho e bohloko, ho kenyelletsa le migraine;
- ho hloka boroko
- ho fokotseha ha kutloelo-bohloko ho ba khopisang;
- metsamao ea boithatelo e etsahalang ka tšohanyetso;
- perseheral nerve dysfunction;
- tahlehelo ea mohopolo
- maikutlo a hoosebumps, tinging kapa ho chesa maikutlo ho hlahang ka boiketsetso;
- mokhathala, ho hloka matla.
Litla-morao li ka hlaha ka lehlakoreng la methapo e meholo ea methapo, mme la baka matšoao a ho otsela.
Ho tsoa tsamaisong ea phefumoloho
Haeba maemo a mabe a ama tsamaiso ea phefumoloho, mokuli o na le matšoao:
- nosebleeds;
- ho eketseha ha asthma;
- maikutlo a ho hloka moea;
- bronchitis kapa pneumonia.
Karolong ea letlalo
Matšoao a latelang a litla-morao a hlaha:
- seborrhea;
- ho fufuleloa ho eketsehileng;
- maikutlo a phahameng ho khanya ea letsatsi;
- xeroderma;
- tahlehelo ea moriri
- matheba a manyane (petechiae);
- hemorrhage letlalong (ecchymosis).
Seborrhea ke e 'ngoe ea litlamorao tse ka bang teng kamora ho sebelisa moriana.
Ho tsoa ts'ebetsong ea genitourinary
Matšoao a mahlakore a hlahang karolong ea tsamaiso ea genitourinary a tšoauoa ka lipontšo tse latelang:
- lefu la liphio
- tlolo ea ts'ebetso ea ho ntša metsi;
- fokotseha potency;
- mali a tsoang ka mpeng kapa ka popelong;
- ho ruruha hoa semelo sa seminal.
Ho tsoa ho tsamaiso ea methapo ea pelo
Mokuli o na le matšoao:
- angina pectoris;
- pelo lippitations;
- phokolo ea mali
- arrhythmia;
- khatello ea mali e phahameng;
- vasodilation;
- ho hloka botsitso sefubeng.
Ho tsoa ho tsamaiso ea pelo le pelo, angina e ka hlaha.
Ho tsoa tsamaisong ea musculoskeletal
Boitšoaro bo fosahetseng bo lebisa matšoao a latelang:
- tšenyo ea mesifa (myopathy);
- bohloko ba mesifa le manonyeletso;
- ho ruruha ha mekotla ea mucous;
- cramps
- eketsa molumo oa mesifa;
- tšenyo ea tendon e nang le kotsi e eketsehileng ea ho phatloha;
- ho ruruha ha manonyeletso.
Allergie
Boitšoaro bo ho kula bo bonahatsa lintho tse latelang:
- lekhopho letlalong;
- feberu ea nettle;
- ho hlohlona
- ho ruruha, ho kenyelletsa le motho;
- ho thothomela ha anaphylactic;
- angioedema;
- erythema exudative.
Bohloko bo bakoang ke ho qeta ho sebelisa moriana o kenyelletsa ho hlohlona.
Litaelo tse khethehileng
Tekanyo ea joala
Tšebeliso e tšoanang ea lihlahisoa tsa atorvastatin le joala ha ea lumelloa.
Tšusumetso ho bokhoni ba taolo ea methapo
Moriana o ka ba le phello e mpe taolong ea lipalangoang, ka hona, o lokela ho hana ho khanna koloi nakong ea kalafo.
Sebelisa nakong ea bokhachane le pelehi
Moriana ona o thibetsoe hore o sebelisoe nakong ea lebone le ho beleha.
Tsamaiso ea Atorvastatin ho bana ba 20
Lilemo tse ka tlase ho lilemo tse 18 ke tlolo ea molao, ka hona, moriana ona ha o sebelisoe molemong oa bana.
Lilemo tse ka tlase ho lilemo tse 18 ke tlolo ea molao, ka hona, moriana ona ha o sebelisoe molemong oa bana.
Sebelisa botsofaling
Moriana ha oa haneloa ho bakuli ba tsofetseng. Moriana o lokela ho nooa ka tekanyo e bontšitsoeng ke ngaka nakong ea lipuisano.
Kopo ea ts'ebetso ea renal e senyehileng
Moriana ha o hloke phetoho ea litekanyetso.
Sebelisa bakeng sa ts'ebetso ea sebete e sa sebetseng
Boteng ba pathologies ea sebete, moriana o ka nooa, empa ka tlhokomeliso, kahoo nakong ea kalafo ho hlokahala ho laola boemo ba transaminase. Ka mekhahlelo e sebetsang ea maloetse a setho, lithethefatsi ha li sebelisoe.
Bongata
Ho sebelisa lithethefatsi ka tekanyetso e kholo ho lebisa ho se sebetseng hantle ha sebete le rhabdomyolysis - boemo bo khetholloang ke ho hloleha ho matla ha renal le ho senyeha ha lisele tsa mesifa. Maemong ana, mokuli o lokela ho isoa sepetlele.
Ho sebelisa lithethefatsi ka tekanyetso e kholo ho lebisa ho se sebetse hantle ha sebete le rhabdomyolysis.
Ho sebelisana le lithethefatsi tse ling
Ho sebelisana ha atorvastatin le lithethefatsi tse ling ho emeloa ke likarolo tse latelang:
- ho theola mokokotlo oa lithethefatsi ha li nooa ka li-antacid tse nang le magnesium kapa aluminium;
- kotsi e eketsehileng ea myopathy ka lebaka la fibrate, cyclosporin, le meriana ea antifungal;
- keketseho e nyane ea tekanyo ea meriana ha u nka Digoxin;
- khatello e eketsehileng ea lithethefatsi ka lebaka la tšebeliso ea li-inhibitors tsa proteinase;
- ho fokotseha ha khatello ea atorvastatin ha u sebelisa colestipol;
- keketseho e matla ea bongata ba moriana maling ha u ntse u nka Itraconazole;
- ho bokellwa ha likarolo tsa sethethefatsi ka tšebeliso ea lero la morara;
- ho fokotseha ha nako ea prothrombin nakong ea tsamaiso ea warfarin;
- kotsi e eketsehileng ea myopathy ka lebaka la keketseho ea khatello ea khatello ea Atorvastatin nakong ea ts'ebeliso e le 'ngoe le Verapamil, Clarithromycin, Diltiazem, Erythromycin.
Li-analog
Mokhoa o tšoanang oa ts'ebetso bakeng sa meriana e latelang:
- Torvacard ke "statin" e nang le phello e tlase ea lipid. E hlahisoa ka sebopeho sa letlapa.
- Atorvox. E fumaneha ka tekanyetso ea 40 mg ea motsoako o sebetsang. Sephutheloana sena se na le matlapa a 30, 40 kapa 60.
- Atoris ke lithethefatsi tse etselitsoeng ho thibela mesebetsi ea HMG-CoA reductase.
Atoris ke e 'ngoe ea lipapatso tsa moriana.
Moriana o boetse o na le mefuta e hlahisoang ke lik'hamphani tse ling:
- Atorvastatin C3;
- Atorvastatin Canon;
- Atorvastatin alkaloid;
- Atorvastatin Akrikhin;
- Teorvastatin Teva.
Lipehelo tsa khefu ea khemisi
E lokolloa moo ho nang le risepe e tlatsitsoeng ka Selatine.
A na nka reka ntle le lengolo la ngaka?
Setlhare se ka rekoa feela ka lengolo la ngaka.
Atorvastatin 20 theko
Litsenyehelo ke li-ruble tse 70-230.
Maemo a polokelo ea moriana
Sehlahisoa se bolokiloe sebakeng se ommeng le se lefifi se sa fumaneheng ho bana.
Sehlahisoa se bolokiloe sebakeng se ommeng le se lefifi se sa fumaneheng ho bana.
Letsatsi la ho felloa ke nako
E loketse lilemo tse 3.
Moqapi
Likhamphani tse latelang li hlahisa moriana
- ALSI Pharma (Russia);
- Teva (Isiraele);
- Vertex (Russia);
- Actavis (Ireland);
- Canonpharma (Russia);
- Akrikhin (India);
- Izvarino Pharma (Russia).
Tlhahlobo ea Atorvastatin 20
Lingaka
Valery Konstantinovich, ngaka ea methapo ea pelo.
Ho sebetsa ha atorvastatin ho latela moetsi. Ho na le lithethefatsi tse ngata tse tšoanang, empa ha se tsona kaofela tse ka thusang mokuli. Lithethefatsi tsa pele ke lithethefatsi tse ntle tse fokotsang lipid, empa li na le litšenyehelo tse phahameng.
Tšebeliso e tšoanang ea lihlahisoa tsa atorvastatin le joala ha ea lumelloa.
Bakuli
Eugene ea lilemo li 45, Penza.
Nakong ea tlhahlobo, sepetlele se fumane cholesterol e phahameng. Atorvastatin e ne e laetsoe ho nka, e neng e lokela ho emisa boemo boo. O ile a nka moriana pele a robala ho fihlela sephutheloana se felile. Ha ho fumanoa botjha, ho ile ha senoloa hore boemo ba cholesterol ha bo fetohe.
Veronika, ea lilemo li 35, Nizhny Novgorod.
Atorvastatin e ne e fuoe ntate, hobane cholesterol e phahameng ke bothata ba lelapa le futsitsoeng. Kamora kalafo, boemo ha bo a fetoha, mme kamora likhoeli tse 6 ho ropoha mokokotlong ho ile ha koaloa, e leng ho ileng ha baka leqhubu la meno. Hona joale ntate o sebelisa moriana o theko e boima makhetlo a mabeli ka selemo, ho seng joalo ba tla khaoloa.
Sergey, ea lilemo li 49, Krasnoyarsk.
Kamora ho hlaseloa ke pelo, o ile a qala ho nka Atorvastatin. Ke se ke qetile lilemo tse fetang tse 5 ke sebelisa moriana ona. Phuputso ea morao tjena e fumane hore maemo a cholesterol a ne a tloaelehile mme ho ne ho se na lebaka la ho tšoenyeha. Ha ho litla-morao ha ho nooa lipilisi.
