Litokisetso tsa kalafo ea kalafo ea methapo ea methapo

E 'ngoe ea mathata a tloaelehileng a lefu la tsoekere ke cerebral arteriosulinosis. Lefu lena le nkuoa e le sesosa se ka sehloohong sa ho holofala le ho shoa hoa baahi.

Ka discepulopia encephalopathy, lesapo la mokokotlo la mokokotlo, le amang phepo e nepahetseng ea lithane tsa boko le ho thusa ho hlaheng ha atherosranceotic stenosis. Hona ho hocha khafetsa ho baka lefu la ischemic le dementia ea methapo.

Kaha lefu lena le na le mathata a mangata a lefu la tsoekere, kalafo ea methapo ea kutlo e nang le lithethefatsi e lokela ho ba tlamo. Empa pele u etsa kalafo ea lithethefatsi, u lokela ho utloisisa lisosa, matšoao a lefu lena le ho etela ngaka.

Likarolo tsa lefu lena

Atherosclerosis ke mofuta o sa foleng oa methapo e meholo ea methapo, e khetholloang ka ho bokellana ha lipids marakong a methapo ea mali le kholo ea lithane tse amanang le tsona. Sesosa se ka sehloohong sa lefu lena ke ho se atlehe ha metabolism ea mafura. Lintho tse ka ntle le tse ka hare li ka lebisa kholo ea lefu lena.

Mabaka a tšoanang a kenyelletsa botsofaling, ha litsamaiso le litho tsa 'mele li qala ho sebetsa hampe ka lebaka la lits'ebetso tsa botsofali. Bong bo boetse bo phetha karolo ea bohlokoa ho hlaheng ha lefu la methapo ea pelo. Kahoo, ho banna, lefu lena le hlaha hangata khahlano le semelo sa estrogen, se amehang ho phatloheng ha triglycerides.

Foreisposition ea lefutso e boetse e bua ka lintho tse sa fetoloeng bakeng sa ponahalo ea liathomo tsa methapo ea methapo liseleng tse ka hare tsa methapo ea mali. Lisosa tse fetolehang tsa lefu lena li kenyelletsa:

1. khatello ea maikutlo
2. tšebeliso e mpe ea joala, ho tsuba;
3. hypercholesterolemia;
4. metabolic syndrome;
5. khatello ea mali e phahameng;
6. hyperglycemia e sa foleng;
7. khaello ea phepo e nepahetseng;
8. boima bo feteletseng;
9. khatello e phahameng ea Homocysteine ​​maling;
10. ho hloleha ha rems.

Psychology e 'ngoe e hlaha khahlano le semelo sa ho se sebetse' meleng, hyperfibrinogenemia. Hoa hlokomeleha hore, ho latela sesosa sa ketsahalo eo, mefuta ea atherosclerosis e khetholloa e le metabolic, amanang le lilemo, chefo, allergic le ho ruruha (syphilis, lefuba).

Haeba lefu le hlaha khahlano le semelo sa khatello ea methapo ea mali, joale se bitsoa hyalinosis. Ha lefu lena le hlaha ka lebaka la ho bokellana ha letsoai la calcium ka methapong ea methapo, ebe mokuli o fumanoa a leacacacosis.

Ho na le mekha e mene ea kholo ea methapo ea methapo. Boemong ba pele, lipid li hlahisa sebopeho, 'me ea bobeli - li-plaque tsa fibrous.

Mokhahlelo oa boraro o tšoauoa ka ho thehoa ha liathomo tsa atherosselotic le ho bokellana ha mesifa ea thrombotic. Boemong ba ho qetela ba lefu lena, atherocalcinosis e etsahala, eo ho eona ho nang le petrification ea li-plaque le define vascular.

Qalong ea nts'etsopele, atherosclerosis ha e bonahale. Ke ka linako tse ling bakuli feela ba tletleba ka mokhathala o sa foleng, ho tsepamisa mohopolo hampe, hlooho e sa utloahaleng.

Ha Psychology e ntse e tsoela pele, matšoao a latelang a ba teng:

• tinnitus;
• Ho tsekela
• tlama khatello ea mali;
• letsoalo
• ho hloka boroko
• ho senyeha ha mohopolo;
• ho se leka-lekane le sepheo sa matsoho;
• ts'ebeliso e mpe mesebetsing ea bonono le ea puo.

Maemong a tsoetseng pele, ho ba le litho tsa 'mele tse sa kopaneng ho tsona, sefahleho sa sefahleho, litho tsa maoto le matsoho. Hape, atherosclerosis ea mohato oa 3-4 e tšoauoa ka letšoao le joalo ka pherekano. Hangata, bakuli ba tletleba ka hore ha ba na matla a ho sebetsa, 'me ho bakuli ba bang, ho hlaha tšenyo e itseng botho.

Pele u nka meriana leha e le efe ea lefutso la methapo ea methapo, ho hlokahala tlhahlobo e phethahetseng. Lithuto tsa laboratori li kenyelletsa liteko tsa mali tse amanang le immunological le biochemical.

Mokhoa o motle ka ho fetisisa oa ho fumana atherosulinosis ke MRI. Ultrasound, angiography le transcranial dopplerography li sebetsa ka tsela e tšoanang.

Melao-motheo e akaretsang ea kalafo

Phekolo ea kalafo ea methapo ea methapo e tlameha ho ba e felletseng hape e na le mekhoa ea matšoao, pathogenetic le khalemelo. Empa pele o nka meriana, lingaka li eletsa bakuli ho lekola lijo tsa bona.

Pheko ea phepo e nepahetseng e tla etsa hore kalafo ea lithethefatsi e sebetse haholoanyane 'me e tla liehisa ho tsoela pele ha lefu lena. Molao-motheo o ka sehloohong oa phepo ea phepo atherossteosis ke ho hana lijo tse mafura tse tsoang liphoofolong, tšebeliso e fokolang ea letsoai le lijo life kapa life tse kotsi (lijo tse potlakileng, soseji, lino-mapholi).

Ka li-pathologies tsa methapo, lingaka li khothaletsa ho lekola khatello ea mali khafetsa, ho lekola maemo a tsoekere le cholesterol maling. Ntho ea bohlokoa ka ho tšoanang ke ho hana lithethefatsi, ho tloaela boima ba 'mele, mokhoa oa letsatsi le letsatsi. Ha rea ​​lokela ho lebala ka ho ikoetlisa ka tsela e leka-lekaneng le ho qoba maemo a sithabetsang.

Haeba atherosulinosis ea methapo ea methapo e fumanoa, kalafo ea lithethefatsi e u lumella ho fumana litlamorao tse latelang:

1. khatello ea khatello ea mali;
2. ho fokotseha ha hypoxia;
3. normalization ea lipid metabolism;
4. nchafatso ea lumen ea vascular.

Phekolo ea kalafo ea methapo ea methapo e kenyelletsa tšebeliso ea lithethefatsi tsa lihlopha tse fapaneng tsa lithethefatsi.

Statins, bile acid sequestrants, antiplatelet agents, vithamine PP, li-fibrate, lithethefatsi tsa anticholesterol le lithethefatsi tse thatafatsang khatello ea mali li sebelisoa.

Maemo

Lithethefatsi tsena li nkuoa e le motheo oa kalafo ea atherosulinosis, kaha li tlosa sesosa sa ponahalo ea sona - hypercholesterolemia.

Pheko ea li-statins ke ho thibela sephiri sa enzyme e phehiloeng e ikarabellang bakeng sa tlhahiso ea k'holeseterole, ho eketsa palo ea "liploprotein" tse nang le "bohlokoa", ho nolofatsa methapo ea methapo ea methapo, methapo ea methapo ea kutlo le ho matlafatsa le ho fepa methapo ea mali.

Lipilisi tse ntle ka ho fetisisa tsa "cera" tse tsoang seretseng tse tsoang sehlopheng sa li-statins tse ncha tsa moloko:

Ntle le taba ea hore li-statin li na le kalafo e matla ea ho fokotsa lipid ka tlase, li na le litla-morao tse 'maloa. Tse tloaelehileng ka ho fetisisa ho tsona ke li-pathologies tsa mesifa ea mesifa, ho kulisoa ke mefuta eohle, ho se sebetse hantle ha tsamaiso ea methapo ea kutlo le ts'ebetso e mpe ea ts'ebetso ea tšilo ea lijo.

Contraindication ho ho nka li-statins - lefu la sebete, bana ba ka tlase ho lilemo tse 8, ho se mamellane ka bonngoe.

Moriana ha ea lumelloa ho sebelisoa haeba ho ka etsoa mokhachane, ho nyeka le ho na le tšoaetso e ngata maling.

Fibrate

Fibroic acid e tsoang ho tsona ke sehlopha sa bobeli se sebetsang sa lithethefatsi bakeng sa ho thatafatsa metabolism ea lipid. Ba fokotsa bongata ba mafura a kotsi 'meleng ka 50%, ba eketsa matšoao a cholesterol e ntle maling. Phello ea kalafo e fumanoa ka ho eketsa bongata ba li-enzyme tse khethehileng tse etsang hore ho tlosoe lipoprotein tse fokolang tse tsoang 'meleng ka bile.

Ka li-plaque tsa atherosclerotic, li-fibrate li behiloe ka li-statins, haholo-holo ha hypercholesterolemia e tsamaisana le triglyceridemia. Empa ka ho hloka mamello ho li-enzyme tsa enzyme ea sebete, li-derivatives tsa fibroic acid li ka nkuoa ka thoko.

Motsoako o sebetsang oa "cerrophal arteriosulinosis" o tsoang sehlopheng sa fibrate ke Fenofibrate. Tekanyetso ea letsatsi le letsatsi ea lithethefatsi e ka tloha ho 140 ho isa ho 400 mg.

Lits'oaetso tsa fibroic acid, joalo ka li-statins, li nkuoa lithutong - ho tloha likhoeli tse 3. Matlapa a tahoa ho fihlela makhetlo a 2 ka letsatsi.

Lithethefatsi tse tummeng tse tsoang sehlopheng sa li-fibrate:

• Bezafibrat. U ka nka sehlahisoa se fihlang ho 0,3 g ka nako e le ngoe.
• Clofibrate. E na le ts'ebetso e hlophisehileng - e thibela enzyme ea sebete, e senya mafura, e fokotsa pono ea mali le mahloriso a uric acid. O ka nwa hofihlella hofihlella ho isa ho 9 pilisi ka letsatsi, lipilisi tse 2-3 ka nako e le ngoe.
• Gemfibrozil. Moriana o nooa 1 (900 mg) kapa 2 (600 mg) hang ka letsatsi pele ho lijo.
• Lipanor Tekanyetso matsatsing a pele a 90 a kalafo ke 100 mg ka letsatsi, ebe e ka eketsoa ho 200 mg. Haeba ho hlokahala, moriana o sebelisoa lilemo tse 'maloa.
• Koprofibrate. E fapana le li-fibrate tse ling ketsong e telele, e fokotsang nako ea kalafo le palo ea litekanyetso tsa moriana. Libeke tsa pele tse 8-12, sethethefatsi se laetsoe ka mokhoa oa monotherapy, ebe ts'ebeliso ea sona e kopantsoe le lithethefatsi tse ling tse khahlanong le atherosselotic.

Litlhahlobo tsa batho ba bangata ba nang le lefu la ho holofala ha litho tsa 'mele li tiisa hore maemong a 90%, li-fibrate li mamelloa hantle. Ka hona, likarabelo tse mpe (allergies, ho nyekeloa le pelo, ho nyekeloa hoa tšilo ea lijo, ho senyeha ha potency) ha li na seoelo. Leha ho le joalo, litabeng tsa tšebelisano-'moho ea fibroic acid e nang le li-statins, ts'ebetso ea sebete e mpefala le ho feta.

Mofuta ofe kapa ofe oa fibrate o kopantsoeng le ho hlaphoheloa hoa mmele oa hepatic kapa hepatic, bokhachane le ho lactation.

Lithethefatsi tse joalo ha li fuoe phoso bakeng sa liphatsa tsa lefutso ho metabolism ea carbohydrate, mme bana le bacha le bona ba hanela ho e sebelisa.

Li-antiplatelet agents le li-sequestrants

Li-antiplatelet agents ke li-agents tse fokotsang bokhoni ba ho kopanya li-enzyme tse bopehileng, tse eketsang phallo ea mali le ho thibela ho etsoa ha methapo ea mali. Setlhare se tsebahalang haholo sa sehlopha sena sa lithethefatsi ke Aspirin.

Melemo ea lithethefatsi ke litšenyehelo tse tlase le ts'ebetso e potlakileng. Leha ho le joalo, o lokela ho tseba hore acetylsalicylic acid e halefisa mucous ea ka mpeng, ka hona e kopantsoe le gastritis le seso.

Lisebelisoa tse ling tse tsebahalang tsa antiplatelet, tšebeliso e tloaelehileng ea tsona e thusang ho qoba ho kenella ha opereishene bakeng sa thrombosis, ke Thrombo ACC, Cardiomagnyl, Clopidogrel.

Li-sequel tsa Bile acid ke sehlopha se seng sa lithethefatsi se fuoeng lefu la mokokotlo oa mokokotlo. Basebelisi ba sebetsa ho latela molao-motheo o ikhethang oa phapanyetsano ea ion ea li-resin. Meriana e tlosa acid e mafura 'meleng, ho kenyelletsa cholesterol e mpe.

Ha ho bapisoa le lithethefatsi tse kaholimo, li-sequestrant tsena li na le katleho e tloaelehileng ea lithethefatsi. Empa li na le menyetla - theko e nepahetseng le kotsi e fokolang ea karabelo tse mpe.

Li-latter tse tummeng:

1. Boholo. Ho emisoa ho nooa ka molomo tekong ea 4 g, ka nako pele ho lijo. Nako ea kalafo e khethoa ke ngaka. Litlamorao tse mpe tse ka bang teng ke tlolo ea tšilo ea lijo, ho fokotseha hoa livithamini tse qhibilihang ka hara 'mele.
2. Colestipol kapa Colestid. E fumaneha ka mokhoa oa matlapa (5 g) le phofo (1 g). Boemong ba pele ba kalafo, tekanyetso e le 'ngoe ea moriana ke ligrama tse 5, kamora moo, palo e ka nyolohela ho 30 gr.
3. Questran e fumaneha ka foromo ea phofo. Tekanyetso ea letsatsi le letsatsi bakeng sa bana ke sachet e le 'ngoe, ho batho ba baholo - li-sachets tse 6. Nakong ea kalafo le moriana, ho khothalletsoa ho noa metsi a mangata.

Lithethefatsi tse ling tse sebetsang

Vitamin PP e bapala karolo ea bohlokoa kalafong ea atherosulinosis. Ntho ena e na le thepa e 'maloa e ntle. E na le hypotensive, anticholesterol, vasodilator le fibrinolytic effect.

Tabeng ea mokelikeli oa ho ruruha ha methapo ea kutlo, nicotinic acid e kenya lipoproteidlipase le ho tlosa mafura acids a mangata, e fokotsa khatello ea kelello ea TG.

Lihlahisoa tse thehiloeng ho Vitamin PP li fumaneha ka mefuta e fapaneng ea litekanyetso mme li nkuoa kamora lijo. Motsoako oa letsatsi le letsatsi o khothalletsoang ke ligrama tse 3-5.

Mofuta o mongata oa lithethefatsi tse thehiloeng nicotinic acid o ka baka ho tuka. Contraindication - urolithiasis, ho hloleha ha sebete, ho se sebetse hantle hantle ha tšilo ea lijo.

Hape, ka atherosclerosis, li-vasodilator li laetsoe. Ba holisa khanya ea methapo ea methapo ea kelello le ho tsamaisa maloetse, a ntlafatsang ho potoloha ha mali le ho eketsa metabolism ea matla a neural.

Lithethefatsi tse sebetsang tsa vasodilator:

• Cinnarizine;
• Norvask
• Nimodipine;
• Lacipil;
• Adalat le ba bang.

Ka thoko, ho bohlokoa ho hlokomela moriana o bitsoang Detralex. Ena ke moriana o hlasimollang o hlatsoang le ho pepeta methapo ea mali ea boko kapele. Empa khafetsa, Detralex e alafshoa bakeng sa ho senya atherosulinosis, kaha e tlosa ho ruruha, ho imeloa le bohloko maotong.

Li-vithamine le liminerale ke karolo ea bohlokoa ea kalafo e rarahaneng bakeng sa ho thibeloa ha methapo ea kutlo ka li-cholesterol plaque. Lintho tse nang le thuso tse hlokahalang bakeng sa methapo ea methapo: livithamini PP, C, B le mohlala oa li-silicon, potasiamo, selenium.

Kaha atherosclerosis hangata e tsamaisana le khatello ea mali ea methapo, lithethefatsi tse matlafatsang li kenyelletsoa kalafong e rarahaneng ea lefu la tsoekere. Indapamide, Captopril, Hydrochlorothiazide, Nifedipine le Carvedilol li na le phello e ntle ea kalafo. 'Me ka mehato e tsoetseng pele ea atherosclerosis, mokuli a ka fuoa marotholi a nang le lithethefatsi tse matla ho hloekisa le ho theola mali.

Ho felisa matšoao a sa thabiseng a li-pathologies tsa vascular, kalafo ea matšoao e etsoa. Khafetsa, ngaka e beha litlhare tsa litlhare, lithethefatsi tsa psychotropic, analgesics, tranquilizer.

Joaloka phekolo ea adjunct e nang le kotsi e eketsehang ea ho bola ha mali, litlolo tse thehiloeng limela tsa litlama li ka sebelisoa. Haeba ho hlokahala, bakuli ba ka tlatselletsa kalafo e felletseng ka litlhare tsa setso.

Ka atherosclerosis ea boko, litlama tse kang periwinkle, balm ea lemone, dill, mint, borax, melilot, meadowsweet, thuso ea clover. Bakeng sa ho hlohlelletsa microcirculation, ho felisoa ha mesifa ea mesifa le ho fokotseha ha mali, ho sebelisoa litokisetso tse nang le ginko-biloba -Tanakan, Ginko Fort le Bilobil.

Tsela eo atherosclerosis e tšoaroang ka eona e hlalositsoe videong ena.