K'holeseterole e phahameng ho lefu la tsoekere ke letšoao le sa thabiseng la mokuli.
Sena se bakoa ke taba ea hore ka keketseho ea boemo ba cholesterol (ka har'a lingoliloeng tsa Amerika "cholesterol"), potoloho e mpe ea methapo ea methapo ea pelo e koetsoe.
Ha boemo ba lipids bo le holimo maling, bo beha menyetla ea ho ba le lefu la sethoathoa, le eona e eketsang kotsi ea tsoelo-pele ea lefu la tsoekere.
Ntlheng ena, ho bohlokoa haholo hore nako le nako u lekole karolelano ea cholesterol ho lefu la tsoekere.
Ho na le mefuta e 'meli ea cholesterol ea endo native, ho latela bongata ba eona, hammoho le liprotheine tsa tsamaiso:
- lipoprotein tse tlaase le tse tlase haholo (LDL, VLDL) li "kotsi" atherogenic lipids mme li kotsi 'meleng;
- lipoprotein tse phahameng le tse phahameng haholo (HDL, HDL), ka lehlakoreng le leng, li na le ts'ebetso ea antiatherogenic le ho thibela kotsi ea ho ba le atherosclerosis ea methapo ea mali.
Batho ba nang le lefu la tsoekere ba tšoauoa ka ho eketseha ha maemo a LDL le ho fokotseha ha maemo a HDL ha ho bapisoa le palo e akaretsang ea batho ba phetseng hantle. Keketseho ea boemo ba matšoao a LDL le TAG e na le kotsi ea ho ba le koluoa ea methapo ea methapo. Metabolism ea "glucose" e senyehileng e lebisa ho se leka-lekanang pakeng tsa likarolo tse peli tsa lipoprotein. Keketseho ea lipids tsa mali ho lefu la tsoekere e amahanngoa le mekhoa e latelang ea methapo ea methapo:
- Mali a mokuli ea nang le lefu la tsoekere a pepesitse ho khomarela le ho pepeseha lipids tsa mahala.
- Ka lebaka la bokuli bo nako e telele, vasotine ea methapo e ea fokola ebile e rata ho holofatsa sebopeho.
- Keketseho ea tsoekere e lebisa hoketseho ea nako ea ho potoloha ha lipoprotein tsa atherogenic serum.
- Maemo a tlase a lipid tsa anti-atherogenic a eketsa kotsi ea likotsi tsa lefu la pelo.
- Ho ba teng ha lipid plaque likepeng ho mpefatsa boemo ba lefu la tsoekere.
- Ho kopana ha li-pathologies ka bobeli ho ntlafatsa phello ea e 'ngoe le e' ngoe.
Mabapi le mekhoa e kaholimo ea tšusumetso, kakaretso ea serum cholesterol ho lefu la tsoekere e matla e lokela ho betoa leihlo khafetsa. Mokuli ea joalo o tlameha ho ngolisa le endocrinologist le therapist.
Boleng ba cholesterol ho lefu la tsoekere
Ho latela lipatlisiso tsa morao-rao tsa kliniki, cholesterol e phahameng ho tsoekere ea lefu la tsoekere e lebisa ho tsoeleng pele ka potlako ea angiopathy mme e eketsa kotsi ea lefu la pelo le methapo.
Le ha ho na le bothata ba kalafo ena e kopaneng, bo arabela hantle kalafong.
Ho lekola khafetsa ho itima lijo ha glycemia, khatello ea mali le khatello ea lipoprotein ho thusa ho ntlafatsa boemo ba mokuli.
Ho lefu la tsoekere la mofuta oa pele (mocha) ka ho lekola boemo ba glycemia khafetsa, keketseho ea boemo ba lipid ha e bonoe. Empa ho bakuli ba nang le lefu la tsoekere la lefu la tsoekere le mofuta oa 2 lefu la tsoekere, boemo bo fapane.
Teko e atolositsoeng ea mali bakeng sa lipids tsa mofuta oa 2 lefu la tsoekere e tšoauoa ka:
- fokotse cholesterol ea HDL;
- maemo a tlase a HDL;
- keketseho ea maemo a LDL;
- maemo a ntseng a phahama a VLDL;
- keketseho ea cholesterol e felletseng;
- maemo a ntseng a eketseha a TAG.
Liphetoho tse joalo profilse ea lipid li lebisa ho pepeseng lipoprotein tsa atherogenic marakong a endothelium 'me li lebisa ho sitisoeng ke leseli la methapo ea methapo. Li-lipids tse nyane tsa li-antiidsogenic lipids ha li khone ho sebetsana le ho eketseha ha liso tsa methapo ea methapo ea methapo ea methapo. Triglycerides e boetse e ama hampe lits'ebetso tsa phetoho ea metabolic ea lipids. Ka lebaka la ho felisoa ha sekepe, hypoxia ea lisele tse fanang ka mali ea hlaha.
Ka khaello ea phepo e nepahetseng le khaello ea oksijene, litho tsa methapo ea methapo lia hlaha, ho hlobaetsang - necrosis. Lefu la tsoekere le cholesterol e phahameng le na le monyetla o moholo oa ho fumana infarction e mpe ea myocardial kapa ho otloa ke lefu la sethoathoa bokong nakong e tlang.
Ntle le moo, lefu la tsoekere le 'meleng oa ka le lefu la tsoekere le tsoela pele le khokahanyo ea tšebetso ea atherosulinotic.
Ho sebelisana ha insulin le cholesterol maling
Ho fihla joale, lithuto li ntse li etsoa ka phello ea insulin ea kantle ho biochemistry ea mali, ho kenyeletsoa le maemong a lipid. Keketseho e eketsehileng ea "insulin" ea mali maling e lebisa keketseho ea karoloana ea lipids tsa atherogenic le ho fokotseha hoa khatello ea li-lipids tsa antiatherogenic. Ntle le moo, litekanyetso tsa cholesterol e phahameng ke tšobotsi ea bakuli ba nang le lefu la insulin e matla ea ho hlola.
Ho ikoetlisa ka matsoho ho lebisa ho fokotseha hoa maemo a cholesterol. Taba ena e bohlokoa bakeng sa botenya ba lelapa kapa bo botšehali. Bakeng sa bakuli ba mofuta oa lefu la tsoekere, ho hlahloba glycemia ka nako e tšoanang ho ka fokotsa cholesterol.
Ka ho beha leihlo hantle tsoekere ea glucose, ho hlokomeleha tloaelo ea cholesterol ea mali. Ka bomalimabe, ka kalafo e sa nepahalang ea hypoglycemic mofuteng oa pele oa lefu la tsoekere, hyperlipidemia e matla le eona ea hlaha.
Sena se lebisa likotsi tse phahameng tsa atherosulinosis sehlopheng sena sa bakuli. Hoo e ka bang bakuli bohle ba nang le lefu la tsoekere, ho senyeha ha senya le methapo ea methapo. Liphoso tse hlahang ho endothelium li bokella limolek'hule tsa cholesterol.
Sena se lebisa kholong e potlakileng ea ntho ea atherogenic mme se eketsa likotsi tsa thrombosis, ho koaloha leseli la methapo le nts'etsopele ea methapo ea methapo ea kutlo.
Mekhoa e meholo ea kalafo
Mokhoa o tiileng oa ho theola cholesterol ea mali ke ka ho fetola mekhoa ea bophelo.
Mokuli o lokela ho qala ho buisana le ngaka ea bongaka bakeng sa likeletso.
Hape hoa hlokahala ho latela ka tieo meriana, e nke ka tieo joalo ka ha u laetsoe ke ngaka.
Litlhahiso tse latelang mabapi le tšebeliso ea mafura li tla ntlafatsa tsela ea lefu lena le boleng ba bophelo ba mokuli:
- Ho sebelisoa haholo ha mafura a monounsaturated le lik'habohaedreite tse potlakileng ho ka eketsa khatello ea cholesterol maling. Tšebeliso ea bona e lokela ho ba le moeli.
- Ha ho na tlhoko ea ho felisa mafura ka botlalo lijong.
- Mafura a bohlokoa ka ho fetisisa lijong ke mafura a polyunsaturated. Baemeli ba khanyang bao e leng mafura a mafura a Omega-3 le Omega-6. Boholo ba li-omega acid bo fumaneha ka oli ea meroho le litlhapi tsa leoatleng.
Mokhoa o netefalitsoeng oa batho oa ho felisa ho fokotseha tsoekere ea mali le ho tloaetsa cholesterol - mokhoa o phetseng hantle, mofuta le mofuta oa phepo e nepahetseng.
Phekolo ea mantlha bakeng sa hypercholesterolemia ke ts'ebeliso ea li-statins. Sehlopha sena sa lithethefatsi se na le phello e phatlalalitsoeng ea antiatherogenic. Mofuta oa 2 oa lefu la tsoekere le cholesterol e phahameng ke maloetse, maemong a mangata, a kopaneng.
Sehlopha sena sa litokisetso tsa meriana le sona se tlameha ho kopanngwa le phetolo ea mokhoa oa bophelo, liphetoho tsa ho ja le ho ruisa ka likarolo tsa semela le mafura a phetseng hantle, hammoho le mesebetsi e tloaelehileng ea letsatsi le letsatsi e entsoeng. Mokhoa o joalo oa phekolo o tla fokotsa kotsi ea koluoa ea pelo le methapo. Phekolo e boetse e itšetleha ka boemo ba lipid, bophelo ba mokuli, litšobotsi tsa lilemo tsa hae le ho ba teng ha lintlha tse kotsi.
Kamano pakeng tsa lefu la tsoekere le atherosclerosis e hlalositsoe videong ena.
