Hoa tsebahala hore nako ea lefu la tsoekere e sokela nts'etsopele ea mathata a mangata, ebe e fetoha lefu le bohloko.
Mathata a metabolite a ama litho tsohle, ho kenyeletsa le pheletso ea methapo. Mathata a kang lefu la tsoekere a kang polyneuropathy, tšenyo ea sebete le li-pathologies tse ling lia ntlafala.
Mafu a joalo a phekoloa ka mokhoa o phethahetseng ke lithethefatsi tse nang le tokelo ea molao Tiogamma, litaelo tsa tšebeliso ea tsona li fapana ho latela mofuta oa tokollo ea pharmacological.
Matšoao a ho sebelisoa
E 'ngoe ea litaba tse hatellang tsa bongaka ke hore phekolo ea mathata a lefu la tsoekere. Lithethefatsi tse ling li ama matšoao a lefu la tsoekere.
Empa mokhoa o tsoetseng pele ka ho fetisisa ke phello e tobileng ho pathogenesis ea lefu lena. E 'ngoe ea mathata a tloaelehileng a lefu la tsoekere ke polyneuropathy.
Psychology ena e lebisa mathateng ka maoto (lefu la tsoekere) hape e tšosa ka ho khaola maoto le matsoho. Mohloli oa lefu lena ke lethathamo la tsoekere e sa tloaelehang ka har'a lisele tse etsang methapo ea methapo ea methapo le methapo ea mali: mahlahana a kotsi a nang le ts'oaetso ea oxidizing - li-radicals tsa mahala - li thehiloe ka ho tsona.
U ka emisa mokhoa oo joang? Tharollo ke ho boloka maemo a tloaelehileng a tsoekere. E 'ngoe ea lintho tse loantšang katleho le mafu a joalo ke thioctic (TK) kapa α-lipoic acid (ALA). Thioctic acid e kenelletse hantle ho metabolism, ka katleho e fokotsa acidity ea lisele, kaha ke antioxidant e matla.
Thiogamma tharollong le matlapeng
Ntle le moo, TC e hlophisa metabolism ea li-carboxylic acid, e sirelletsang li-hepatocytes tsa sebete. ALA e eketsa phokotso ea cellular ho insulin, e phethang karolo ea bohlokoa ho lefu la tsoekere. Kajeno, sesebelisoa se ikhethang se thehiloeng ho thioctic acid, Thiogamma, se hlahile 'marakeng.
Moriana ona o na le botsoalle 'meleng, kaha ALA ka boeona ke sehlahisoa sa tlhaho sa metabolic. E ama ka matla mehato ea metabolic, moriana ona o fokotsa tsoelo-pele ea mathata ebile o fokolisa matšoao a 'ona. Ho lefu la tsoekere, thiogamma e ka fokotsa le litekanyetso tsa lithethefatsi tse theolelang tsoekere.
Setlhare se sebetsa hantle:
- lefu la tsoekere;
- ho taoa haholo;
- joala polyneuropathy le polyneuropathy ea joala;
- ho fokola ha mafura a hepatocytes (mohlala, ka joala) le li-pathologies tse ling tsa sebete.
Sebopeho
Karolo e ka sehloohong ke thioctic acid (TC). Motsoako o khothalelitsoeng oa kalafo ke 600 mg / ka letsatsi.
Tsepamiso ea maikutlo e na le:
- meglumine theoctate (ntho ea mantlha) - e lumellana le 600 mg ea TC;
- macrogol (4000 mg) le meglumine (ho fihlela 18 mg);
- metsi d / i - 20 di ml
Tharollo ea infusion (foromo e felileng) e kenyelletsa:
- letsoai la meglumine ea TC (ntho ea mantlha) - e lumellana le 600 ml ea thioctic acid;
- macrogol le meglumine;
- metsi d / i - 50 di ml.
Foromo ea Letlapa e na le:
- TK - 600 mg;
- cellulose ea microcrystalline le lactose monohydrate - 49 mg ka ngoe;
- sodium caramellose - 16 mg;
- magnesium stearate - 16 mg le talc - 2 mg.
Khetla ena e kenyeletsa:
- talc - 2.0 mg;
- macrogol - 0,6 mg;
- hypromellose - 2,8 mg;
- sodium lauryl sulfate - hoo e ka bang 0, 025 mg.
Fomu ea ho lokolla le ho paka
Lifekthering, Tiogamm e hlahisoa ka mefuta e latelang:
- tharollo ea ente e sebelisitsoeng ka mokhoa o hlakileng e hlakileng ea li-vials. E na le 'mala o botala ba' mala o moputsoa. Li-botlolo tse 50 ml li entsoe ka khalase e sootho 'me li koaetsoe ka sethala sa rabara, se sirellelitsoeng ka holimo ka cap ea aluminium. Se seng le se seng se na le mokotla o bobebe oa polasetiki. Sephutheloana sena se na le libotlolo tse ka bang 10 tse arohantsoeng ke karata ea karata;
- tsepamisa mohopolo bakeng sa infusion - e hlakileng pepeneneng ea 20 ml. E na le 'mala o moputsoa bo botala. Mohope o mong le o mong o entsoe ka khalase e sireletsang e 'mala o sootho' me e tšoailoe ka letheba le lesoeu. Letlapa la karete e nang le likarolo tse arohanang e etselitsoe li-ampoules tse 5. Pakete e ka ba le lipolanete tse 1,2 kapa 4;
- biconvex kapa matlapa a 600 a li-ml tse ngata. Likotoana tse 10 li kentsoe ka har'a lipolanete tsa foil kapa tsa PVC blister. Li na le 'mala o moputsoa o bobebe. Ho na le likotsi mahlakore ka bobeli. Motsoako o bobebe oa 'mala o mosehla oa bonahala manonyeletsong. Ho paka ka mokhoa oa lebokose la likarete tse nang le marang-rang a 3, 6 kapa 10.
Ketso ea pharmacological
Karolo e ka sehloohong ke thioctic acid. E hlahisoa ke 'mele o phetseng hantle' me e kenella ka mafolofolo ho metabolism ea mafura, oxidative le carbohydrate 'meleng.
Ho kenella ho metabolism ea lipid, TC e fokotsa ho potoloha ha mafura a fokolang haholo, ka lebaka leo palo ea lipids tse phahameng haholo plasma ea mali e eketsehang.
Ka hona, thioctic acid e imolla methapo ea mali liseleng tse mafura tse ngata. TK e na le phello e ntle ea ho khahlisa. Bokhoni bona ba thioctic acid ke litholoana tsa mosebetsi o ntlafalitsoeng oa sebete.
Thiogamma e boetse e sebelisoa ka mafolofolo kalafong ea lefu la tsoekere, ho ntlafatsa phepo e nepahetseng ea methapo ea kutlo ea methapo. E fokotsa ho ruruha ha lisele ho tsoekere le ho thibela ho bokellana ha glycogen bokong, e le hepatoprotector e ntle. Melemo ea pharmacological ea lithethefatsi e ts'oana le ketso ea vithamine B.
Moriana o boetse o tumme haholo ho cosmetology. Kaha alpha lipoic acid e na le phello e molemo letlalong la sefahleho:
- e fokotsa wrinkles, esita le sefahleho se tebileng sa sefahleho;
- e kokobetsa letlalo;
- e thusa makhopho.
Litaelo tsa ho sebelisoa
Melao ea ho sebelisa moriana o fapana ho ea ka mofuta oa tokollo.
Matlapa a 600 mg a khothalletsoa hore a nooe hang ka letsatsi.
E le hore e se ke ea senya khetla, ha ea lokela ho hlafuneloa. Ho hlapa ka metsi. Thupelo ea kalafo e laetsoe ke ngaka ho latela lipontšo tsa motho ka mong.
Ka tloaelo matlapa a nooa ho tloha khoeli ho isa ho matsatsi a 60. Pheta kalafo makhetlo a 2-3 ka selemo. Haeba Thiogamm e sebelisoa e le infusion (entravenous infusion), litekanyetso tsa eona ka letsatsi le tsona ke 600 mg. Ke feela TC e ngata e fumanehang ho ampoule ka 'ngoe, e bonolo haholo.
Moriana o fanoa butle butle, ho fihlela halofo ea hora, ho tlosa litla-morao. Pheko ntlheng ena e nka libeke tse 2-4. Nako ea kalafo e khuts'oane (e bapisoang le matlapa) e hlalosoa ke ho hlohlona ho phahameng ha moriana ke lero la mali.
Ho lokisa tharollo ea infusion ho tsoa ho tsepamiso, o tlameha ho etsa tse latelang: litaba tsa ampoule e le 'ngoe li tsoakane le 100-250 ml ea tharollo ea sodium chloride (9%).
Motsoako o hlahisoang o koaheloa hang-hang ka kesi e khethehileng ea opaque ebe e tsamaisoa e le lerotholi la methapo.
Tsamaiso e nka metsotso e 20 ho isa ho e 30. Tharollo ea Thiogamm e entsoeng hantle e ka bolokoa nako e telele ho isa ho lihora tse 6.
Contraindication
Contraindication mabapi le ts'ebeliso ea Tiogamma e kenyeletsa:
- lefu la sebete la sebete;
- kotsi ea ho lactic acidosis (haholo-holo ka li-infusions tsa drip);
- seso sa ka mpeng;
- lefu la pelo;
- ho omella;
- lefu la tsoekere
- joala bo sa feleng;
- maqeba
- ho fufuleloa hantle ka mpeng ha glucose (ha u sebelisa matlapa);
- ho mpefala ha myocardial infarction;
- bongoana;
- boimana
- ho se mamelle lintho tse ka sehloohong: tse fumanoeng, kapa lefa.
Litlamorao
Nakong ea kalafo ka litlamorao tsa lithethefatsi hoa khoneha:
- dyspepsia
- ka seoelo (kamora ho li-droppers) mesifa ea mesifa e ka bonoa;
- hlooho e opang (hangata e emisa ha infusion e lieha);
- thrombophlebitis;
- tlolo ea tatso;
- redness sebakeng sa ente (urticaria);
- ho senyeha hoa pono (ka lefu la tsoekere).
Ho sebelisana le meriana e meng
Thiogamma hammoho le lithethefatsi tse ling e na le tšusumetso e latelang:
- phello e khahlanong le ho ruruha ea glucocorticoids ea matlafatsoa;
- Litlhare tsa hypoglycemic li ntlafatsa phello ea kalafo. Ka hona, ts'ebeliso ea bona e kopaneng le Tiogamm e kenyelletsa ho fetola litekanyetso ho fokotsa;
- Thiogamm ha e lumellane le tharollo ea Dextrose le Cisplacin.
Lipehelo tsa thekiso, bophelo le polokelo ea bophelo
Setlhare se hasoa ka mokhoa o netefalitsoeng oa "receptor". Kamoreng e lefifi le e ommeng, ka mocheso oa 20-25 ° C. Pakete ha ea lokela ho senyeha. Bophelo ba Shelf ea lithethefatsi ke lilemo tse 5.
Litaelo tse ikhethang
Phekolo ea lefu la tsoekere le Tiogamma e kenyelletsa ho lokisoa ha lethal dose la kalafo le neng le boletsoe esale pele la insulin.
Setlhare se na le matla a tonic le antioxidant, ka hona e ka sebelisoa e le sehlahisoa sa litlolo.
E lokela ho nka sebopeho ka mokhoa oa libotlolo (eseng ho tsepamisa mohopolo). Likahare tsa eona, ntle le ho hlapolla, li ka sebelisoa hang-hang letlalong. E tlameha ho hloekisoa pele ho ts'ebetso e sebetsang ea moriana.
Theko le hore na u ka e reka kae
Litsenyehelo tsa moriana ka tekanyetso ea 600 mg li fapana hanyane ho latela mofuta oa tokollo.
Kahoo litheko tsa Tiogamma ho la Russian Federation li tjena:
- ho tsepamisa mohopolo (botlolo e le 'ngoe) - li-ruble tse 210;
- tharollo ea li-ruble (1 ampoule) - li-ruble tse 200;
- matlapa (pakete ea li-pcs tse 30) - li-ruble tse ka bang 850.
O ka reka Tiogamm ho k'hemisteng efe kapa efe kapa ho reka inthaneteng.
Li-Analogs (tsa Serussia le tsa linaha tse ling)
Lithethefatsi tse joalo tsa lapeng li kenyelletsa: Corilip le Oktolipen, Lipothioxone. Litaba tse tsoang kantle ho naha ea Jeremane: Thioctacid, Berlition.
Sebelisa nakong ea bokhachane, bongoaneng le botsofaling
Nakong ea kemolo, ho sebelisa moriana ona ha ho ratehe, hobane ho ba le phello e mpe ho lesea.
Moriana o thibetsoe ka thata ho bana ka lebaka la mathata a tebileng a ka bang teng ho bakuli ba banyenyane. Setlhare sena se khothalletsoa batho ba baholo ba nang le lefu la tsoekere la mofuta oa 2.
Ka joala
Joala bo nyenyefatsa phello ea lithethefatsi, ka hona ts'ebeliso ea ethanol ts'ebetsong ea kalafo ha e khothalletsoe.
Litlhahlobo
Thiogamm e tumme ka ho loketseng har'a batho ba lefu la tsoekere.E boetse e hlokahala hara bakuli ba tloaeloang ke li-neuropathie, kaha e sebetsa e le prophylaxis le kalafo bakeng sa li-pathologies tsena mme eu lumella ho boloka matla a ho sebetsa ka lilemo tse ngata.
Ntle le moo, sethethefatsi (bakeng sa nete e khuts'oane) se thusa ho qoba nts'etsopele ea maloetse a endocrine. Ho latela maikutlo, ho hlokometsoe hore ha ho na lebaka la ho tšaba litlamorao tsa meriana ena, hobane lipontšo tsa tsona li fumaneha seoelo.
Livideo tse amanang
Mabapi le ts'ebeliso ea alpha-lipoic acid ha ho phekoloa lefu la tsoekere le amanang le tsoekere ho video: