Ciprolet 500 ke e 'ngoe ea lithethefatsi tse sebetsang ka ho fetisisa tsa fluoroquinolone tse nang le likopo tse ngata. E ka sebelisoa bakeng sa kalafo le thibelo ea mafu a fapa-fapaneng a tšoaetsanoang le a tšoaetsanoang, empa pele ho qala kalafo, ho kgothaletsoa ho netefatsa ho ts'oaroa ha likokoana-hloko tsa kokoana-hloko ena.
ATX
Moriana ona ke oa sehlopha sa meriana ea "quinolones" 'me se na le khoutu ea ATX ea J01MA02.
Ciprolet 500 ke e 'ngoe ea lithethefatsi tse sebetsang ka ho fetisisa tsa fluoroquinolone tse nang le likopo tse ngata.
Lokolla liforomo le sebopeho
Cyprolet e etsoa ka mefuta e latelang ea litekanyetso:
- matlapa a kopaneng a enteric;
- tharollo ea infusion;
- leitlho.
E le ntho e sebetsang, ciprofloxacin e sebelisoa ho tsona.
Tekanyetso ea 500 mg e na le mofuta oa moriana oa litlhare feela. Matlapa a tšoeu, a pota-potile, a na le mahlakore ka bobeli. Karolo e sebetsang ea hydrochloride e teng ka bongata ba 0,25 kapa 0,5 g. Motheo o kenyelletsa le:
- crodarmellose sodium;
- microcellulose;
- magnesium stearate;
- silicon dioxide;
- drug talc;
- starch ea poone.
Ho koahela filimi ho entsoe ka motsoako oa hypromellose, dimethicone, titanium dioxide, macrogol, talc, sorbic acid le polysorbate.
Matlapa a 10 ajoa ka marang-rang. Pakete ea lebokose le kantle. Pitsa e le 'ngoe ea blister le litaelo tsa tšebeliso li kenngoa ka ho eona.
Ciprolet e sebelisoa e le sethethefatsi sa antibacterial.
Ketso ea pharmacological
Ciprolet e sebelisoa e le sethethefatsi sa antibacterial. Karolo ea eona e sebetsang ke ciprofloxacin, lithibela-mafu tsa maiketsetso tsa letoto la fluoroquinolone. Mohato oa tšebetso ea komporo ena ke thibelo ea li-topoisomerase tsa mofuta oa II le IV, tse ikarabellang bakeng sa ho hlaka hoa libaktheria tsa DNA.
Motsoako oa lithibela-mafu o bontša thepa ea bactericidal. Tlas'a tšusumetso ea eona, tlhahiso ea DNA e koetsoe, kholo le ho tsoaloa hape ha likokoana-hloko li emisitsoe, li-membrane le membrane ea lisele li felisoa, e leng se bakang lefu la libaktheria. Sena se o lumella ho senya likokoana-hloko tse senang gram tse sethaleng se sebetsang le phomolong. Moriana o boetse o sebetsa ho likokoana-hloko tsa gram tse ntle, empa feela ha a le sethaleng sa ho ikatisa.
Ciprofloxacin ha e bontše ho hanyetsa sefapano ka penicillin, aminoglycosides, tetracyclines, cephalosporins le lithibela-mafu tse ling tse sa thibeleng gyrase ea DNA. Ka hona, e sebetsa hantle moo lithethefatsi tsena li hlolehang. E sebetsa khahlanong le likokoana-hloko tse ngata, ho kenyelletsa:
- Moraxella catarrhalis;
- Salmonella
- Shigella
- likhukhuni;
- Klebsiella;
- Proteus
- lethathamo;
- brucella;
- entero le cytobacteria;
- li-vibrios;
- mala, hemophilic, Pseudomonas aeruginosa;
- chlamydia
- ba bang ba staph le streptococci.
Fecal Enterococcus le Mycobacterium avium li hloka tšebeliso ea lithethefatsi ka tekanyetso e phahameng. Ha e sebetse hantle khahlano le pneumococcus, treponema, ureaplasma, mycoplasma, bacteroids, flavobacteria, Pseudomonas maltophilia, Clostridium Hardile, Nocardia asteroides, li-anaerobes tse ngata, ha e robe microflora ea tlhaho ea ka mpeng le ea botšehali.
Resistance e ka fapana ha nako e ntse e ea 'me ho latela geolocation. Khanyetso e fumanoeng e hlaha butle butle.
Mofumahali
K'hemik'hale e sebetsang e kenngoa ka mpeng e nyane, e fihla e kenella maling ka lihora tse 1-2 kamora hore e noe matlapa. Lijo li theola sekhahla sa ho amoheloa, empa ha li ame bioavailability, e ka fihlelang 80%. Motsoako oa litlhare o kenella maro a sa tšoaneng (peritoneal, ophthalmic, bile, mkojo, mathe, lymph, synovia, sputum, seminal plasma), e tsamaisoa hantle liseleng:
- sebete
- lefu la nyooko;
- litho tsa botona tsa botšehali;
- mala;
- peritoneum;
- Prostate;
- matšoafo le pleura;
- pampitšana ea liphio le tsa mkojo;
- manonyeletso a kopaneng;
- meralo ea letlalo le letlalo.
Ka nako e ts'oanang, likhakanyo tsa lisele li makhetlo a 'maloa (ho fihla ho 12) li phahame ho feta tsa plasma.
Moriba o fetela ka lebeseng la matsoele, o tšela placenta le mothapo oa mali le bokong. Likahare tsa ciprofloxacin ka har'a mokelikeli oa "cerebrospinal fluid" ha ho na ts'ebetso ea ho ruruha li eketsa karolo ea 8 lekholong ea mali a eona maling, 'me ka meninges e tlotsitsoeng e ka fihla ho 37%. Puisano le liprotheine tsa mali - 20-40%.
Ho lokisa karolo e itseng ea lithethefatsi Ciprolet 500 ho etsoa ke sebete, metabolites e bonts'a ketso e itseng.
Ho etsa karolo e itseng ea moriana ho etsoa ke sebete, metabolites e bontša ketso e itseng. Ho fihlela 70% ea tekanyetso e nkuoeng e bontšoa ka sebopeho sa eona sa pele. Moroalo o moholo oa ho pepesa o oela liphio. Ho felisoa ha halofo ea bophelo ke lihora tse 3-6. Ka ho se sebetse hantle ha renal, letšoao lena le ka kopola makhetlo a mabeli, empa sethethefatsi ha se eketsehe, kaha mantle a sona a ntlafala. Ka ts'ebetso e tloaelehileng ea menoana, makhopho a ntšoa 1% ea molumo oa pele.
Ho thusang
Sesebelisoa seo ho buuoang ka sona se reretsoe ho loants'a microflora ea pathogenic, e amehang ka ciprofloxacin. Matšoao a ho khethoa ha Cyprolet:
- Tšoaetso ea phepelo ea methapo ea methapo: tšoaetso e matla ea phefumoloho, bronchitis, bronchiectasis, pneumonia ea baktheria, haeba e sa bakoe ke pneumococcus, mathata a cystic fibrosis, legionellosis, empyema le abscess ea matšoafo.
- Maloetse a Otolaryngological: sinusitis, otitis media, mastoiditis, pharyngitis, agranulocytic tonsillitis.
- Tšoaetso ea Urogenital: pyelonephritis, cystitis, tubulointerstitial nephritis, oophoritis, endometritis, salpingitis, orchitis, epididymitis, prostatitis, balanoposthitis, gonorrhea.
- Peritonitis le liso tse ling tsa ka mpeng. Mona, lithibela-mafu li sebelisoa e le karolo ea phekolo e rarahaneng.
- Cholecystitis, ho kenyelletsa ho sa hlalosoe, cholangitis, empema ea gallbladder.
- Maloetse a amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa lijo tse amanang le tsamaiso ea lijo tsa mafu a amanang le lijo tsa lijo tse amanang le ho ja, ho kenyelletsa shigellosis, feberu ea typhoid, lets'ollo la baktheria.
- Ts'oaetso ea lits'oants'o le likarolo tse poteletseng: li-abscesses, phlegmon, furunculosis, maqeba, ulcers, ho chesa ka matšoao a tšoaetso ea bobeli.
- Tšoaetso ea musculoskeletal: myositis, bursitis, tendosynovitis, osteomyelitis, ramatiki e sa foleng.
- Sepsis, bacteremia, anthrax ea ts'oaetso, ts'oaetso ho bakuli ba nang le ts'oaetso e fokolang (ka neutropenia kapa lithethefatsi tsa immunosuppressive).
- Thibelo ea ts'oaetso, ho kenyelletsa Neisseria meningitidis le Bacillus anthracis.
Tsiprolet 500 e ke ke ea sebelisoa ha u beleha ngoana.
Contraindication
Moriana ha oa lokela ho sebelisoa haeba motsoako o sa mamellehe kapa o na le nalane ea hypersensitivity ho lithethefatsi tsa fluoroquinolone. Lits'ebetso tse ling tse mpe tse kenyang:
- pseudomembranous enterocolitis;
- ho nka tizanidine ka lebaka la kotsi ea hypotension e matla;
- bongoaneng le bohlankana (ho lumelloa ho sebelisa Ciprolet bakeng sa bana ba lilemo tse 5 ho hatella tšebetso ea Pseudomonas aeruginosa boteng ba cystic fibrosis, hammoho le ho felisa le ho thibela ts'oaetso ka Bacillus anthracis);
- ho ba le ngoana;
- lebone.
Ka tlhokomelo
Ho laoloa ka mokhoa o ikhethileng ho bakuli ba tsofetseng, bakuli ba nang le ho senyeha ha hepatic-renal, ho haella ka mokokotlo, nakong ea lefu la sethoathoa.
U ka nka Ziprolet 500 joang
Moriana o sebelisoa feela joalokaha o laetsoe ke ngaka. Lipilisi li ka nooa ho sa tsotelehe lijo. Haeba u noella ka mpeng e se nang letho, joale ba tla nka khato ka potlako. Li metsoa li felletse 'me li hlatsuoa ka metsi. Ts'ebeliso ea tšebeliso ea lithethefatsi ena e kopantsoe hammoho le lino tse nang le litholoana tse matlafatsoang ka liminerale, le lihlahisoa tsa lebese (ho kenyelletsa le yogurt ho li-capsules e le monyetla).
Moriana oa Ciprolet o sebelisoa feela joalo ka ha u laetsoe ke ngaka.
Lidao li khethoa ka bonngoe ho latela matšoao, ho tsitsinyeha ha pathogen, ho teba le ho hlaka ha lesion. Batho ba baholo ba nka matlapa a 500 mg habeli ka letsatsi. Haeba ho hlokahala, tekanyetso e le 'ngoe ea eketseha. Motsoako oa letsatsi le letsatsi ha oa lokela ho feta 1.5 g, haeba ho hlokahala, sethethefatsi se tsamaisoa ka phepelo ea morao ho ts'ebetsong ea molomo. Liente tsa methapo ea kutlo ha li etse.
Litekanyetso tsa pele le tsa tlhokomelo li khothaletsoa ho bakuli ba nang le ts'ebetso ea ho hlaphoheloa ha meno. Ka tumello ea creatinine ka tlase ho 30 ml / min, nako e pakeng tsa litekanyetso li nyolohela ho lihora tse 24. Bakeng sa bana le ba lilemong tsa bocha, motsoako o thibelang likokoana-hloko o khethoa ha ho hlokahala, hobane o ka baka arthropathy. Methapo e baloa ho latela boima ba ngoana.
Lits'oaetso tse ling tse tšoaetsanoang le tse fokolisang (ts'oaetso ea likarolo tsa masapo-mokokotlo, litho tsa ka mpeng, le pelvis) li hloka ts'ebeliso ea litlhare tse ling tsa antibacterial ka ho tšoana. Nako e tloaelehileng ea kalafo ke libeke tse 1-2. Ka linako tse ling mokhoa oa phekolo o nka likhoeli tse 'maloa.
Na hoa khoneha ho nka moriana oa lefu la tsoekere?
Ha ho na contraindication bakeng sa ts'ebeliso ea Ciprolet ke batho ba lefu la tsoekere. Bokhoni ba moriana oa ho baka ho feto-fetoha ha maemo a tsoekere ntlheng e le 'ngoe kapa e' ngoe bo lokela ho tsotelloa.
Ha o nka Ciprolet, ho thibela tšebetso ea hematopoietic le phetoho ea sebopeho sa mali ho ka etsahala.
Litlamorao
Moriana e thibelang likokoana-hloko e mamelloa hantle, empa maemong a mang e ka baka liketsahalo tse bohloko.
Phekolo ea ka mpeng
Bakuli ba tletleba ka ho nyekeloa, ho hlatsa, nts'etsopele ea lets'ollo, bohloko ba ka mpeng, botlaela. Khafetsa, candidiasis ea mucosa ea molomo, laryngeal edema, ho ruruha ha masapo a mokokotlo, ho se sebetse hantle ha sebete (ho kenyeletsa ho se sebetse ha sebete), hepatitis, necrosis ea tishu, cholestasis, ts'ebetso e eketsehileng ea li-enzyme tsa sebete, pseudomembranous enterocolitis.
Hematopoietic litho tsa ka hare
Ho sitisa ts'ebetso ea hematopoietic le phetoho sebopeho sa sele ea mali, ho kenyelletsa leukocytosis le pancytopenia, lia khonahala.
Tsamaiso ea methapo e bohareng
Ho ts'oaroa ke letsoalo, migraines, mokhathala o matla, asthenia, ho tšoenyeha ho hoholo, ho hloka boroko, khatello ea maikutlo, ts'ebetso ea kelello, mathata a kopanetsoeng a ho sisinyeha, ho thothomela, lipontšo tse tsitsipano, paresthesia, neuropathy, tatso le ho fofonela, ho lla litsebeng, ho khutla ha kutlo ho utloang, diplopia le litlolo tse ling tsa pono.
Ho tsoa ts'ebetsong ea moroto
Ho nka moriana o thibelang likokoana-hloko ho ka baka pherekano tšebetsong ha liphio, ponahalo ea methapo ea mali ka har'a moroto, nts'etsopele ea "crystalluria" le keketseho ea mahlaseli a creatinine.
Ha u nka Cyprolet 500, ho tsekela, migraine le mokhathala li ka hlaha.
Ho tsoa ho tsamaiso ea methapo ea pelo
Ho ka ba le tachycardia, hypotension, ho thunya ho chesang, bofubelu ba sefahleho, ho lelefatsa nako ea QT mokhatlong oa pelo, pirouette arrhythmia, vasculitis.
Allergie
Hangata, ho fetoha ha letlalo ho etsahala: lekhopho, ho ruruha, hyperemia, ho hlohlona, urticaria. Ka linako tse ling ho hlaha makhopho habonolo. Photosensitization, erythema e mpe, necrolysis ea lits'oants'o, bronchospasm, ho makala ha anaphylactic, feberu, bohloko ba mesifa le manonyeletso lia khoneha.
Litaelo tse khethehileng
Ka liso tse matla, ts'oaetso ea lefua la streptococcal, mafu a bakoang ke likokoana-hloko tsa anaerobic, kalafo e nang le Tsiprolet e lokela ho tlatselletsoa le baemeli ba bang ba antimicrobial.
Letšollo le hlahisoang ka lebaka la ho sebelisa lithibela-mafu ha le khone ho felisoa ka thuso ea lithethefatsi tse hatellang ts'ebetso ea motor ea mala.
Ciprofloxacin e ka baka ho ruruha ha tendon, ho tsietsana ha sethoathoa le nts'etsopele ea bonohe.
Tekanyo ea joala
Ha u ntse u sebelisa lithibela-mafu, lino tse tahang le litlhare tse nang le joala ha lia lokela ho nooa.
Tšusumetso ho bokhoni ba taolo ea methapo
Litlamorao tse tsoang tsamaisong ea methapo ea kutlo le litho tsa kutlo li ka etsahala, ka hona, ha ho khanna koloi le ho laola mekhoa e ka bang kotsi, tlhokomelo e lokela ho nkuoa.
Sebelisa nakong ea bokhachane le pelehi
Bakhachane le batsoetse ntle le ho tlosa ngoana letsoele ho tsoa letsoeleng, ho sebelisa sethethefatsi sena ho kopantsoe.
Ho laela Cyprolet ho bana ba 500
Nako ea lilemo ke lilemo tse 18. Setlhare se ka sebelisoa bongoaneng feela bakeng sa kalafo le thibelo ea anthrax ea pulmonary kapa ho loants'a Pseudomonas aeruginosa ho bakuli ba nang le cystic fibrosis. Empa maemong ana, ho bonolo haholo ho sebelisa litekanyetso tsa 250 mg, ho fapana le 500 mg.
Bongata
Matšoao a bosholu bo feteletseng:
- hlooho e bohloko
- vertigo;
- cramps
- thothomela
- bohloko bo ka mpeng;
- hallucinations;
- renal hepatic ho senyeha;
- crystalluria;
- mali ka moroto.
Hoa hlokahala ho phumola mpa le ho etsa kalafo e nang le matšoao. Ho bohlokoa ho hlokomela mosebetsi oa liphio le ho latela mokhoa o ntlafalitsoeng oa ho nooa. Ho buoa ka meno ha ho na thuso.
Basali baimana le baimana ntle le ho tlosa ngoana lesea letsoele, ho nkoa liphrolet ho tsoa ho eena.
Ho sebelisana le lithethefatsi tse ling
Ciprolet e eketsa litaba tsa Theophylline ho plasma ea mali, e liehisa ho felisoa ha li-antidiabetic molomo, xanthines le NSAIDs (ntle le Aspirin), e ntlafatsa nephrotoxicity ea cyclosporin le katleho ea Warfarin. Litokisetso tsa magnesium, tšepe, aluminium le zinki li liehisa ho amoheloa ha ciprofloxacin, ka hona, u hloka ho li sebelisa ka nako ea lihora tse 4.
Phekolo eo ho buuoang ka eona e tsamaisana le litlhare tse ling tsa antibacterial:
- Metronidazole;
- Vancomycin;
- cephalosporins;
- penicillin;
- aminoglycosides;
- marangrang.
Ho felisoa ha eona ho fokotseha kapele ho boteng ba Probenecid, mme hammoho le NSAIDs, kotsi ea lipontšo tse kholisang e eketseha.
Li-analog tsa Tsiprolet 500
Litšoantšo tse amanang le lithethefatsi:
- Koprofloxacin.
- Cyprocinal.
- Afenoksim.
- Tsiprosan.
- Tsiproksin.
- Medociprine.
- Ciprinol.
- Quintor et al.
Lithethefatsi tse kopaneng le motsoako o mong oa motsoako ka sebopeho, ka mohlala, Ciprolet A e nang le tinidazole, li ka fuoa.
Lipehelo tsa khefu ea khemisi
E fanoe ke lengolo la ngaka.
Theko
Litsenyehelo tsa litafole tsa 500 mg li tsoa ho li-ruble tse 54. ka sephutheloana (li-pcs tse 10).
Maemo a polokelo ea Tsiprolet 500
Setlhare se bolokiloe ka blackout ka mocheso ho fihlela ho + 25 ° C sebakeng se sa fumaneheng ho bana.
Letsatsi la ho felloa ke nako
Lilemo tse 3
Setlhare se bolokiloe ka blackout ka mocheso ho fihlela ho + 25 ° C sebakeng se sa fumaneheng ho bana.
Litlhahlobo mabapi le Tsiprolet 500
Moriana o fumana litlhahlobo tse ngata tse ntle tse tsoang ho lingaka le bakuli.
Lingaka
Kartsin N.S., Urologist, Tver
Motsoako ona oa fluoroquinolone o sebetsa hantle haholo ho pepeseheng ho hoholo ha lefu la setho la botšehali. Ho eletsoa ho jala pejana.
Turimova O. N., setsebi sa kalafo, Krasnodar
Setlhare se na le ts'ebetso e mengata e fapaneng. E sebetsa ka potlako. Litlamorao ha li na seoelo.
Bakuli
Lyudmila, ea lilemo li 41, motse oa Kerch
Ke nkile lipilisi tsa angina. Matsatsi a pele ho ne ho le thata ho a koenya. Empa sephetho se khahlisitse: 'metso o phetseng hantle' me ha ho litla-morao.
Anatoly, ea lilemo li 37, Ryazan
Ke nwa moriana ona ka ho ata ha bronchitis e sa foleng bakeng sa matsatsi a 5, leha matšoao a se a nyamela ka matsatsi a 3-4. Hang ha ngaka e beha moriana o mong oa ho loantša lithibela-mafu, ka lebaka leo letšollo le matla le ileng la qala. Kahoo ke tla tšoaroa feela ke Cyprolet. Mmele wa hae o bona betere ho feta.
