Cocarnit ke litokisetso tse rarahaneng tse nang le livithamini tsa B le triphosadenine. E sebelisoa ho phekola lefu la tsoekere polyneuropathy, neuralgia, bohloko ba mesifa. E boetse e sebelisoa ho ntlafatsa metabolism ho mafu a tsamaiso ea methapo ea pelo.
ATX
A11DA (Vitamin B1).
Cocarnit ke litokisetso tse rarahaneng tse nang le livithamini tsa B le triphosadenine.
Lokolla liforomo le sebopeho
Lyophilisate bakeng sa ho hlophisoa ha tharollo ea 'mala o pinki, li-ampoules tse 3 tsa 3 ml ka setsing sa sele. 1 ampoule e na le:
- Trifosadenin 10 mg.
- Nicotinamide - 20 mg.
- Cyanocobalamin - 0.5 mg.
- Cocarboxylase - 50 mg.
Baeti: glycine 105.8 mg, li-preservatives (methyl parahydroxybenzoate - 0,6 mg, propyl parahydroxybenzoate - 0,15 mg). Solvent: lidocaine hydrochloride - 10 mg, metsi a ente - 2 ml.
Ketso ea pharmacological
Setlhare ke motsoako oa livithamini tse peli, coenzyme e le ngoe le ntho ea metabolic.
Trifosadenin ke sesebelisoa se nang le litlamo tsa macroergic tse fanang ka matla tsamaisong ea methapo le mesifa ea pelo. E na le litlamorao tse matlafatsang. E phahamisa methapo ea methapo ea pelo le ea methapo. E ntlafatsa metabolism ea lithane tsa methapo.
Trifosadenin ke sesebelisoa se nang le litlamo tsa macroergic tse fanang ka matla ho mesifa ea pelo.
Nicotinamide - vithamine PP, e ameha lits'ebetsong tsa matla, karabelo ea potoloho ea Krebs. E ntlafatsa mmele o nang le "carbohydrate" le "protein" metabolism. Lowers cholesterol.
Cyanocobalamin - vithamine B12. Khaello ea ntho ena e lebisa ho mokoko o sa tsitsang, ts'ebetso e sa sebetseng ea mokokotlo oa mokokotlo le tsamaiso ea methapo ea kutlo. Ke monehelo oa lihlopha tsa methyl ho fokotsa boemo ba Homocysteine, bo lematsang tsamaiso ea methapo ea pelo. E khothalletsa ho nchafatsoa hoa sele.
Cocarboxylase ke coenzyme ea enboxme ea carboxylase e laolang ho hokahanya le ho hasoa ha lihlopha tsa carboxyl ho li-alpha-keto acid. E lebisa ho li-antihypoxants, e eketsa ho hanyetsa ha myocardial ho haella ha oksijene. E fokotsa mokokotlo oa lactate le pyruvate ho cardiomyocytee le 'mele. E kenyelletsoa ho motsoako oa li-acid tsa acid, liprotheine, mafura.
Mofumahali
Trifosadenin e robehile ka har'a lisele ho ba phosphates le adenosine, e kenyellelitsoeng ts'ebetsong ea sebopeho sa molek'hule ea ATP bakeng sa litlhoko tsa matla tsa mmele, ho kenyelletsa lithane tsa methapo le pelo.
Cocarboxylase e kenella ka har'a lisele, e kenngoa lits'ebetsong tsa metabolic, ebe ea bola. Lihlahisoa tse senyehileng li tšeloa ka har'a moroto.
Cyanocobalamin e tsamaisoa ke liprotheine tsa transcobalamin liseleng, li bolokiloe haholo ke sebete, moo e tsoang teng ke bile. Ho fetolela ho 5-deoxyadenosylcobalamin. Protein e tlamang ke 0.9%. E hlotsoe kapele ka mor'a taolo ea batsoali. Ts'oarello e phahameng e fihlella hora e le 'ngoe ka mor'a ente ea intramuscular. Ho felisoa ha halofo ea bophelo ke matsatsi a 500. E pepesitsoe boholo ke mala - hoo e ka bang 70-100%, 7-10% e tlohela 'mele ka liphio. E kenella ka har'a placenta, hape le ka lebese la matsoele.
Cyanocobalamin e bolokoa ka ho khetheha ke sebete, moo e tsoang le bile e nang le karolo e itseng.
Nicotinamide e tsamaisoa ka potlako ho pholletsa le 'mele. E entsoe ka sebete ke nicotinamide-N-methylnicotinamide. Ho felisoa ha halofo ea bophelo ke lihora tse 1,3. E pepisoa ka liphio, clearance 0.6l / min.
Matšoao a ho sebelisoa
E bontšoa bakeng la lefu la tsoekere le lefu la tsoekere (goosebumps, neurogenic pain), lefu la pelo le pelo, methapo ea methapo ea methapo, ka nako ea kamora ho hlaphoheloa ke stroke le ho otloa ke pelo, nakong ea ts'ubuhlellano ea nakoana ea ischemic, ho akheha. Litaelo tsa tšebeliso li bontša sciatica, radiculitis.
Contraindication
Contraindicated haeba ho na le hypersensitivity ho moriana, ho eketseha ha mali, mokhachane, ho lactation, ka tlase ho lilemo tse 18, ho hloleha ha pelo haholo, thromboembolism, hemorrhagic stroke, bronchitis e fokolisang, lefu la mokokotlo la mokokotlo, lefu la mokokotlo oa lesapo la mokokotlo kapa lefu la mokokotlo.
U ke ke ua sebelisa lithethefatsi bakeng sa khatello ea maikutlo e sa laoleheng, hypotension, ho lelefatsa nako ea QT, ho tsitsipana ha pelo le bradyarrhythmias.
U ke ke ua sebelisa lithethefatsi bakeng sa khatello ea mali e sa laoleheng.
U ka nka Cocarnit joang?
Ha o sebelisa sethethefatsi sena, o hloka ho tseba ho se sebelisa.
Seo u lokelang ho se etsa
Dilute 2 ml ea 0.5% (10 mg) kapa 1 ml ea 1% ea lidocaine ka 1 ml ea metsi bakeng sa ente.
Ho nka moriana oa lefu la tsoekere
Ente e kenngoa ka har'a mesifa. Khoso ke matsatsi a 9 bakeng sa ampoule e le 'ngoe. Kamora ho tlosoa ha lefu la bohloko bo hlobaetsang, kalafo e ntse e tsoela pele - liente li etsoa ka matsatsi ohle a 2-3. Thuto ke libeke tse 3.
Litlamorao
Moriana o ka baka litlamorao.
Phekolo ea ka mpeng
Ho nyekeloa ke pelo, ho hlatsa, lets'ollo - ka seoelo.
Hematopoietic litho tsa ka hare
Keketseho ea palo ea lisele tse khubelu tsa mali, lisele tse tšoeu tsa mali, liplatelete.
Tsamaiso ea methapo e bohareng
Monate, hlooho ea hlooho, vertigo.
Ho tloha lehlakoreng la tsamaiso ea methapo e bohareng, litla-morao ka mokhoa oa hlooho ea hlooho lia khoneha.
Ho tloha letlalong le linama tse ka tlasana
Ho tloha letlalong le linama tse ka tlasana - li-rashes, ho hlohlona, bofubelu ba letlalo, makhopho, mofufutso.
Ho tsoa ho sesole sa 'mele
Edema ea Quincke, ho hlohlona, lekhopho.
Ho tloha lehlakoreng la pelo
Arrhythmia, tachy le bradycardia, bohloko ba sefuba, khatello e fokotsehileng.
Allergie
Ho thothomela ha anaphylactic, lekhopho la letlalo.
Mokuli a ka ba le lipontšo tsa lefu la ho kula ka mokhoa oa lekhopho.
Litaelo tse khethehileng
Phekolo le sethethefatsi e lokela ho tsamaea le kalafo ea lefu la tsoekere ka thuso ea meriana ea hypoglycemic. Haeba matšoao a mpefala kapa ho se na liphetoho tse ntle, leano leo lea lokisoa.
Tharollo e sebelisoa hang kamora ho itokisa. E lokela ho ba le 'mala o pinki. Ha e fetoha, sethethefatsi se ke ke sa sebelisoa.
Tšusumetso ho bokhoni ba taolo ea methapo
Litla-morao li ka khoneha - ho tsekela, ho akheha. Ha li etsahala, u ke ke ua khanna likoloi le mekhoa e rarahaneng.
Litla-morao li ka khoneha - ho tsekela, ho akheha.
Sebelisa nakong ea bokhachane le pelehi
E netefalitsoe. Ha ba sebelisa lithethefatsi, ba hana ho fepa.
Litekanyetso tsa "Cockarnit" bakeng sa bana
Moriana o kopantsoe ho fihlela a le lilemo li 18.
Sebelisa botsofaling
Phetoho ea mori ha e hlokehe.
Bongata
Ka lebaka la dikahare tsa vithamine PP ka tšebeliso ea nako e telele, setlhare se ka baka lefu la mafura ka lebaka la khaello ea lihlopha tsa methyl. Ka overdose ea cyanocobalamin, boemo ba folic acid bo fokotseha.
Ho sebelisana le lithethefatsi tse ling
Cyanocobalamin ha e lumellane le livithamini tsa B1, B2, B6, folic, ascorbic acid, tšepe tse boima (De-nol, Cisplatin), joala.
Cyanocobalamin ha e lumellane le joala.
Ka tšebeliso e tšoanang ea li-biguanides (Metformin) tse nang le lithethefatsi tse nang le mamello ea tsoekere e ngata, lithibela-mafu tsa aminoglycoside, salicylates, potasiamo, colchicine, anticonvulsants, ho amoheloa ha vithamine B12 ho fokotsehile.
Bakeng sa ho qoba khatello ea maikutlo, u ke ke ua sebelisa lithethefatsi tse eketsang ponahalo ea mali.
Cyanocobalamin ha e tsamaisane le chloramphenicol.
E ntlafatsa phello ea vasodilating ea dipyridamole.
Dino - Caffeine, Theophylline - bahanyetsi ba lithethefatsi.
Ha o sebelisoa ka pelo glycosides, kotsi ea litla-morao ea eketseha.
Nicotinamide e ntlafatsa phello ea lithethefatsi tse khahlanong le ho tšoenyeha, ho theoleha le ho fokotsa khatello ea meriana
Xanthinol nicotinate e fokotsa phello ea lithethefatsi.
Moqapi
World Medical Limited.
Li-analog
Ha ho na chelete e nang le sebopeho se tšoanang hantle. Leha ho le joalo, ho na le lithethefatsi tsa metabolic - sodium adenosine triphosphate, cocarboxylase, matlapa a nicotinic acid, cyanocobalamin.
Lipehelo tsa khefu ea khemisi
E fanoe ke lengolo la ngaka. Lenane B.
Theko ea Cocarnith
Theko ea li-ampoules tse 3 ke li-ruble tse 636.
Maemo a polokelo ea lithethefatsi Kokarnit
Boloka sebakeng se omileng ka mocheso oa + 15 ... + 25 ° С.
Letsatsi la ho felloa ke nako
Lilemo tse 3 Solvent ke lilemo tse 4.
Litlhahlobo mabapi le Kokarnit
Nastya
Setlhare ha se theko e tlaase, empa bohloko bo nang le radiculitis bo tlosoa hantle. Ho phunyeletsoa liente tse 12.
Katherine V.
Mofuta oa 2 oa lefu la tsoekere ke bokuli bo tebileng. E iponahatsa e le mahlaba matsohong le maotong. Ho fetile libeke tse 3. Matšoao a polyneuropathy a fokotsehile haholo. Ho se ho le bonolo ho tsamaea.
Peter
Ke kula ka lefu la tsoekere la mofuta oa 2 le angina pectoris. Ngaka e ile ea laela hore letsatsi le leng le le leng u noe moriana ka ampoule e le 'ngoe e le hore bohloko bo fela. Ke qetile matsatsi a 5 ke hlabe, bophelo ba ka bo ntlafala, bohloko ba ka bo matsohong a ka bo kokobetse. Le khatello e ile ea putlama hanyane mme bohloko ba pelo bo ile ba fokola khafetsa.
