K'holeseterole e eketsehileng ea plasma ke boemo bo kotsi. Ho ba teng ha maemo a feteletseng a karolo ena 'meleng ke e' ngoe ea lintlha tsa mantlha ponahalong ea mathata a pelo le methapo ea methapo.
Ho thibela nts'etsopele ea mathata a tebileng le mathata a amanang le methapo, ho ea lingakeng ho laela bakuli ba noang lipilisi tse fokotsang lipid.
Ketso ea lichelete tse joalo e etselitsoe ho fihlela ho fokotseha hoa boemo ba cholesterol maling a mali a mokuli.
E 'ngoe ea mekhoa ea sejoale-joale e nang le lipid tse fokotsang mantsoe ke lipilisi tsa ho theola cholesterol Novostat.
Ts'ebetso ea pharmacological ea Novostat
Matlapa a Novostat ke sethethefatsi sa hypolipidemic se sehlopha sa li-statins. Ts'ebeliso ea eona e thusa ho fokotsa tsitsipano ea plasma ea cholesterol e felletseng le LDL. Ntle le moo, kalafo ea Novostat e ka fokotsa palo ea apolipoprotein B le triglycerides.
Ts'ebeliso ea moriana e etsa keketseho e sa tsitsang ea palo ea lipoprotein tse phahameng haholo.
Ka lebaka la kalafo ka sethethefatsi sena, ho na le tšusumetso e ntle lits'ebetsong tsa ho khutlisetsa mesebetsi ea epitheli ho ba teng ha mafu a bona a le teng.
Ts'ebeliso ea moriana nakong ea kalafo e ntlafatsa boemo ba methapo ea pelo, e thusa ho ntlafatsa methapo ea mali ea rheological. Tšusumetso ea lithethefatsi 'meleng e ka fokotsa monyetla oa lefu le tsoelo-pele ea lefu la pelo
Ho feta moo, sethethefatsi se phatlalalitse litla-morao tsa antioxidant le antiproliferative.
Phello ea hypolipidemic ea ts'ebeliso ea lithethefatsi e amahanngoa le ho fokotseha ha cholesterol e felletseng ka lebaka la ho fokotseha hoa bongata ba LDL.
Ho fokotseha ha lipoprotein tse fokolang tsa methapo e itšetlehileng ka tekanyetso mme ha ho supe ka phetoho ea mola, empa ke e hlahang.
Mofuta oa tokollo le sebopeho sa moriana
Moetsi o fa Novostat ho bakuli ka sebopeho sa li-capsule tsa "gelatin" tse tiileng tsa opaque.
Novostat ke setlhare se entsoeng ka maiketsetso.
Bokantle ba matlapa a soeufetse ka 'mala. K'hasete e 'ngoe le e' ngoe e na le cap kapa e bobebe ea beige cap.
Li-capsules, ho latela polasetiki, ho ka ba le li-milligram tse 10, 20, 40 le 80. Li-capsules li na le litaba tse lumellanang tsa atorvastatin. Karolo ena ke karolo ea mantlha e sebetsang. Motsoako o sebetsang ka har'a li-capsules o ka sebopeho sa "calcium" sa atorvastatin.
K'hapete e 'ngoe le e' ngoe e boetse e na le mefuta e fapaneng ea metsoako e bapalang karolo e thusang.
Likarolo tsena ke tse latelang:
- lactose monohydrate;
- cellcose ea microcrystalline;
- sodium lauryl sulfate;
- povidone K-17;
- calcium carbonate;
- sodium carboxymethyl starch;
- magnesium stearate.
Sebopeho sa capsule ea lithethefatsi e na le likarolo tse latelang:
- Dae ke tshehla oxide e tshehla.
- Tekanyetso ea titanium.
- Gelatin ke setsi sa koaelo.
Karolo e sebetsang ke inhibitor e khethiloeng ea 3 hydroxy-3-methylglutaryl coenzyme A-reductases (HMG-CoA reductases. Enzyme ke karolo ea mantlha mokokotlong oa karabelo e fetolang 3-hydroxy-3-methylglutaryl-CoA ho mevalonate, e leng moetapele oa pele). sterols.
Setlhare se rekisoa ka lipakete; bongata ba moriana o le ka har'a liphutheloana tse 10 ho isa ho tse 300.
Matšoao le contraindication bakeng sa ts'ebeliso
Ha o rekisa moriana, sephutheloana ka seng se na le litaelo tse qaqileng tsa tšebeliso.
Pele o sebelisa Novostat, ketelo e tlamehang ho ngaka e eang le ho fumana likeletso mabapi le boitšoaro ba litla-morao tsa mmele tse sebelisang sesebelisoa sena ea hlokahala.
Matšoao a sebelisoang ho latela litaelo, ke maemo a mangata a mmele oa mokuli.
Matšoao a sehlooho ke a latelang:
- hypercholesterolemia ea mantlha ho ea ka Fredrickson, mofuta IIa;
- Hyperlipidemia e kopaneng;
- dysbetalipoproteinemia;
- hypertriglyceridemia ea lelapa e loantšanang le lijo tsa hypocholisterin;
- homozygous hypercholesterolemia e nang le katleho e tlase ea kalafo ea ho ja;
- thibelo ea mantlha ea mafu a pelo le a methapo ho bakuli ntle le ho ba le matšoao a bokuli ba lefu la pelo, empa ka ho ba teng hoa mabaka a tlhabollo;
- thibelo ea bobeli ea mafu le methapo ea pelo le methapo ea methapo ea kutlo ho fokotsa lefu, ho fokotsa menyetla ea ho otloa ke pelo le stroke.
Ho latela litaelo, sethethefatsi sena se na le litlolo tse 'maloa tsa ho li sebelisa e le moemeli oa kalafo.
Li-contraindication tse ka sehloohong ke tse latelang:
- Ho ba teng ha hypersensitivity ho likarolo tsa mantlha kapa tse thusang tsa moriana.
- Ho ba teng ha mafu a sebete a sebetsang ho mokuli kapa ho fumanoa ha li-transaminases tsa sebete tsa plasma ho motho.
- Lilemo tsa mokuli li ka tlase ho lilemo tse 18.
- Nako ea kemaro le nako ea ho anyesa.
- Boteng ba ho se mamellane ha lactose ho batho, khaello ea lactase le ho ba teng ha glucose-galactose malabsorption syndrome.
Tlhokomeliso e eketsehang e lokela ho bonoa ha ho fanoa ka litlhare ho bakuli ba sebelisang joala hampe, bakuli ba nang le nalane ea lefu la sebete, hammoho le bakuli ba fumanoeng ba e-na le likhathatso tse matla tekong ea li-electrolyte, mathata a endocrine le metabolic, le khatello ea mali ea methapo.
Ntle le moo, ha e khothalletsoe ho sebelisa moriana ka mor'a ho kenella ka ho pharalla le ho na le likotsi le mafu a mesifa ea marapo.
Litaelo tsa tšebeliso ea lithethefatsi
Setlhare se etselitsoe tsamaiso ea molomo. Novostat e lumelloa ho nkoa ka nako efe kapa efe ea letsatsi, ho sa tsotelehe mofuta oa lijo.
Pele o sebelisa moriana, ho khothaletsoa ho fihlella taolo ea boemo ba cholesterol ka ho sebelisa lijo tsa phepo e nang le cholesterol e fokolang likarolong tsa lijo. Ntle le moo, ho khothalletsoa hore pele ho kalafo ea lithethefatsi tloaelo ea boemo ba cholesterol 'meleng ka ho eketsa moroalo' meleng le ho theola boima ba 'mele ha o le matla haholo.
Ha u fana ka litlhare, matlapa a lokela ho nooa ka nako e le ngoe le phepo ea hypocholesterol. Mokuli o lokela ho latela lijo tse se nang k'holeseterole nakong eohle ea kalafo.
Litekanyetso tsa Novostat li kanna tsa fapana ho ea ka 10 ho isa ho 80 mg ka letsatsi. Tekanyetso ea moemeli e sebelisoang e khethoa ke ngaka e tsamaeang ka bonngoe, ho nahana ka liphetho tsa tlhahlobo le litšobotsi tsa 'mele oa mokuli.
Tekanyetso e phahameng e lumelletsoeng ts'ebeliso ke 80 mg ka letsatsi.
Boemong ba pele ba kalafo kapa ka keketseho ea litekanyetso, litekanyetso tsa cholesterol ea plasma li lokela ho betoa leihlo ka mor'a libeke tse ling le tse ling tse 2,4. Haeba ho hlokahala, ho latela sephetho sa taolo, ho etsoa phetoho ea moriana e sebelisitsoeng.
Ho tlosoa ha ts'ebetso ea liphio ha ho ame karolo ea karolo e sebetsang karolong ea mali, ka hona, boteng ba li-pathologies tse joalo, tokiso ea litekanyetso ha e hlokehe.
Ha o sebelisa moriana ho batho ba tsofetseng, liphetoho tsa lethalamo ha li hloke ho nahanela lilemo tsa mokuli.
Tabeng ea kalafo ka nako e le 'ngoe le Novostat le Cyclosporine, litekanyetso tsa ea pele ha ea lokela ho feta 10 mg ka letsatsi.
Ho hlokahala tlhokomelo e khethehileng ha o sebelisa lithethefatsi ka nako e le ngoe le li-inhibitors tsa HIV tsa protease C le inhibitors ea hepatitis C.
Litla-morao nakong ea phekolo le Novostat
Litla-morao tsohle tse bang teng ha o sebelisa meriana li ka aroloa ka lihlopha tse latelang - hangata, hangata, hangata, hangata, le ka seoelo ha hlaha.
Litla-morao li ka ama tsamaiso ea mali, boits'ireletso ba mmele, methapo, phefumoloho, tsamaiso ea methapo, masculoskeletal le tsamaiso ea ho ikatisa.
Ntle le moo, litla-morao li ka ama litho tsa kutlo le litho tsa pono.
Hangata, litlamorao tse latelang tsa ho sebelisa meriana li ea pele:
- Mokhoa oa mali ke thrombocytopenia.
- Tsamaiso ea 'mele ea ho itšireletsa mafung - litla-morao, ho ferekana hoa anaphylactic.
- Ho tloha lehlakoreng la ts'ebetso ea methapo - hlooho ea hlooho, ho tsekela, pherese, hypesthesia, amnesia, maikutlo a senyehileng a tatso, ho hloka boroko, peropheral neuropathy, maemo a sithabetsang.
- Karolong ea litho tsa pono - ho fokotseha hoa pono ea mahlaba le pono e holofetseng.
- Litho tsa kutlo - tinnitus mme, maemong a sa tloaelehang, tahlehelo ea kutlo.
- Ho tloha ts'ebetsong ea ho phefumoloha - nasopharyngitis, nosebleeds, bohloko bo ka mpeng.
- Ho tsoa ho ts'ilo ea lijo - mokhoa oa ho nyekeloa ke pelo, ho akheha, ho ts'oaroa khafetsa, dyspepsia, lets'ollo, ho lora, ho khothaletsa ho hlatsa, bohloko bo ka mpeng, pancreatitis e matla.
- Ka lehlakoreng la sebete, nts'etsopele ea hepatitis, cholestasis, ho hloleha ha sebete, jaundice ea cholestatic.
- Integument - alopecia, lekhopho la letlalo, ho hlohlona ha letlalo, urticaria, erythema multiforme, chefo e ka fokotsang ea epidermal.
- Ho tloha tsamaisong ea masculoskeletal - myalgia, atralgia, bohloko ba maoto le matsoho, mesifa ea mesifa, bohloko ba mokokotlo, bohloko molaleng, bofokoli ba mesifa.
- Sistimi ea ho ikatisa - gynecomastia, ho hloka matla.
Motsoako o tobileng o khahlanong le Novostat overdose ha o tsejoe. Boemong ba morao, kalafo ea matšoao e ea etsoa. Hemodialysis ha e na thuso ka lebaka la sebopeho sa li-complexes lipakeng tsa protheine ea plasma ea mali le atorvastatin.
Litlhahlobo le litlhahlobo mabapi le lithethefatsi
Novostat e hlokahala hore e bolokoe mochesong o ka tlase ho 25 degrees zero ka hofeta zero. Sebaka sa polokelo se lokela ho omella ebe se lefifi. Hape, sebaka sa polokelo ha sea lokela ho fumaneha ho bana le liphoofolo tsa lapeng.
Bophelo ba sefuba sa lithethefatsi ke lilemo tse tharo. Kamora nako ena, matlapa a tlameha ho lahloa.
Litsenyehelo tsa moriana ho Russian Federation ka nako eo li ka fapana mme ho latela sebaka sa thekiso le k'hamphani e kenyang tšebetso ea thekiso, hammoho le ka palo ea li-capsules tse sekoahelong.
Ka karolelano, theko ea lithethefatsi e tloha ho li-ruble tse 300 ho isa ho tse 600.
Li-analog tsa Novostat 'marakeng oa litlama ke:
- Atorvastatin;
- Atoris;
- Torvas
- Liprimar;
- Vazator;
- Tulip;
- Anvistat;
- Lipitor;
- Ator.
Litlhahlobo tsa mokuli mabapi le lithethefatsi li maqhubu, tse ka etsahalang haholo ka lebaka la bongata ba litlamorao tse tsoang ho ts'ebeliso ea lithethefatsi le litšobotsi tsa likokoana-hloko tsa bakuli ba nang le cholesterol e phahameng 'meleng.
Empa ho lokela ho hopoloa hore lithuto tsa tliliniki li tiisa ts'ebetso e phahameng ea lithethefatsi ntoeng khahlanong le cholesterol e phahameng 'meleng.
Mokhoa oa ho fokotsa cholesterol e hlalositsoe videong ena.
