Lisosa tsa metabolic syndrome le mekhoa bakeng sa kalafo ea eona

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"Ho se ho bolaoa", eo ho thoeng ke phepo ea mafu a tsamaeang le metabolic syndrome.

Ntle le phetoho ea mekhoa ea bophelo le kalafo e lekaneng, litlamorao tsa lefu la kelello li ka ba ovary ea polycystic, ho nyekeloa ke pelo, stroke, lefu la tsoekere, ischemia, gout le atherossteosis.

Ke eng e bakang liphetoho tse joalo 'meleng, lisosa tsa bona ke eng,' me ho ka etsoa eng ho qoba boemo bo joalo?

Metabolic syndrome ke eng?

Motsoako oa phapang ea metabolism ea endocrine 'meleng o amanang le ho se sebetse hantle ha lintho tse amohelang cellular le tšebetso e sa lekaneng ea insulin li bitsoa metabolic syndrome. Ke eng, puo e bonolo ha ho bonolo ho e hlalosa.

Ka 'mele o phetseng hantle, ka mor'a ho ja, tsoekere e hlahisoa ka har'a sebete' me e hasoa ke mali ho ea lithong tsa litho. Makhopho a makhopho a hlahisa insulin. Hormone e ntlafatsa li-membrane tsa sele ho amohela glucose, ka lebaka leo tsoekere e kenang liseleng, moo e fetoleloang matla.

Tlas'a tšusumetso ea mabaka a bakoang ke ho hlaka, ho kenella habonolo hoa li-cellular receptor ho li-hormone hoa fokotseha, ho kenngoa ha tsoekere ho tsona ho thata, mme e qala ho bokellana maling. Ho haella ha karabelo ea cellular ho insulin ho bitsoa ho hanyetsa insulin mme ka lebaka leo, boemo bona ba pathological bo ka kenya letsoho likhatellong tse tebileng. Ho ea ka ICD 10, lefu lena ha le bonoe e le lefu le ikemetseng mme le ka tsamaisana le mafu a mang.

Hangata, ka tlolo ena, ho fumanoa li-pathologies tse 'maloa:

  • ischemia;
  • Mofuta oa 2 lefu la tsoekere;
  • botenya
  • khatello ea mali

Ka motsoako ona oa maloetse, menyetla ea ho ba le lefu la ho fokola ha masapo, stroke kapa lefu la pelo e eketseha haholo.

Metabolic syndrome e ka se phekolehe ka botlalo. Ho tseba ka nako le kalafo e nang le bokhoni ho ka lokisa mathata a metabolic le ho thibela ho hlaha ha mathata.

Mochine le lisosa tsa nts'etsopele

Pathogenesis ea lefu lena ke ho emisa karabelo e tloaelehileng ea cellular ho insulin e bakoang ke ho kopanngoa ha boima ba 'mele le ho hloka ho sisinyeha. Ho ea ka lipalo-palo, hoo e batlang e le halofo ea baahi ba Europe, ba khethang mokhoa oa ho phela ka mokhoa o sa tloaelehang, e tloaetse ho ba maemong a phelisang.

Makhopho a sefahleho a amohela letšoao la hore tsoekere ha e kenngoe liseleng ebe e qala ho hlahisa insulin ka phetetso. Ka lebaka leo, lihormone li bokellana haholo, e leng se hlahisang phetoho ea metabolism ea lipid le kholo e potlakileng ea botena.

Ka lebaka leo, mmele o bokella cholesterol e ngata, e koalang methapo ea mali mme e thusa ho eketsa khatello. Ka lebaka leo, ts'ebetso ea pelo e ferekane. E eketseha maling, tsoekere e baka ho se sebetse hantle ha metabolism ea protheine mme e baka hyperglycemia.

Liphetoho tsena tsohle tsa methapo ea methapo li tsoela pele butle butle, ntle le ho bonts'a matšoao a boletsoeng, a thatafatsang tlhahlobo ea methati methapong ea pele ea sebopeho sa lefu la setho.

Hangata, lefu la kelello le fumanoa ho banna kamora lilemo tse 40. Basali ba hlaseloa habonolo ke lefu lena kamora ho fihlela lilemo tse 50.

Ntle le ho ikoetlisa ka tlase, lintlha tse latelang li khona ho tsosa mohopolo:

  1. Lijo tse se nang phepo - ho lemalla lijo tse nang le tlala, tse thehiloeng ts'ebelisong ea kcal e ka tlase ho sekete ka letsatsi, ho lebisa ho takatso e sithabetsang ea 'mele ea ho beha likhalori tsohle tse tsoang lijong ka pokellong ea mafura. Lijo tse nang le lijo tse nang le mafura a mangata le tse nang le lik'habohaedreite li baka kholo ea tsoekere ea mali le "lipid deposition" tse bolokiloeng ". Lijo tse nang le lijo tse nang le lik'hilojule tse tlase tse phahameng le tse phahameng li thusa hore ho be le mathata a mangata a metabolism le hore cell cell e be teng habonolo.
  2. Heredicial factor - e fetisoang ke lefa, mofuta o fetotsoeng oa liphatsa tsa lefutso:
    • liphetoho tsa sebopeho sa cellular moo palo e sa lekanyetsoang ea li-receptor e thehiloeng teng;
    • karabelo ea receptor e theohileng ho insulin;
    • ho se khonehe ha makhopho ho hlahisa lihormone tse "tloaelehileng";
    • ho hloleha ha boits'ireletso ba mmele, bo qalang ho kopanya li-antibodies tse fokotsang ts'oaetso ea li-receptor.
  3. Phetoho mohaleng oa lihormone ke keketseho ea testosterone ho basali le ho fokotseha ha eona ho banna, hammoho le ho se sebetse hantle ha tšoelesa ea qoqotho ho lebisa ho hlahisoeng ha lisele tsa lipid le ho hanyetsa insulin.
  4. Boroko ba ho robala - Tšenyo ea boko ka lebaka la tlala ea oksijene e etsa hore ho ntšoe hormone e fokotsang kutloisiso ea methapo ea kutlo.
  5. Ho sebelisa litlhare ka lithethefatsi tsa lihormone le corticosteroid.
  6. Mathata a methapo - phetisetso e sa sebetseng ea ts'usumetso ea methapo, e fokotsang tlhahiso ea lihormone le ho amohela receptor.
  7. Phekolo e sa laoleheng - e lebisa ho tlala ea moea ea li-tishu, tse amang kutloelo-bohloko ea methapo.
  8. Ho eketsa tekanyetso ea lihormone nakong ea kalafo ea insulin - tšebeliso e ngata ea "overdose" e kenya letsoho ho tliseng litheko tsa lisele ho insulin.

Liponahatso tsa lefu lena

Pathophysiology ea lefu lena e bontša ka ho hlaka ho ba sieo ha matšoao a boletsoeng, e leng ho lebisa tlhokomelo e nakong ka nako ea kholiseho ea boemo ba methapo.

Ka bonohe, lefu lena le iponahatsa e le mofuta oa liphetoho tse joalo:

  • ponahalo ea likarolo tse bohlokoa tsa mafura a ka mpeng (mahetleng, molaleng, mpa le thekeng);
  • bofubelu bo bonoa sefubeng le molaleng, bo bakoa ke tlolo ea phepelo ea mali le khatello e phahameng ea mali (ho feta 130/85).

Litletlebo tsa mokuli li thehiloe ponahalong ea matšoao a latelang:

  • masisa-pelo;
  • litlhaselo tsa migraine;
  • ho fufuleloa ho eketsehileng, haholo bosiu;
  • bofokoli, tšabo le ho fokotseha ts'ebetso;
  • tšilo ea lijo, ho nyekeloa le pelo le ho thatafala ha defecation;
  • tlhoko e eketsehileng ea lipompong;
  • ho omisoa ha mucous membrous ea cavity ea molomo le lenyora le ntseng le eketseha ho bonoa;
  • sekhahla sa pelo sea eketseha;
  • tahlehelo ea tšebelisano;
  • ho se ts'oanehe, mabifi le lipontšo tse ling tsa ho tsitsipana kelellong.

Mathata le litlamorao

Ho nts'etsapele nako e telele ebile e sa laolehe, kamora lilemo tse 10-15 ho tloha qalong ea ts'ebetso ea mathata a endocrine, syndrome ea metabolic e lebisa ho fokotseha ha mesebetsi ea thobalano le ho ba le bana. Ho banna, khahlano le semelo sa lefu lena, ho hloka taolo ea erectile hoa bonoa, ho basali, lefu lena la methapo le baka mathata a kemolo.

Ntle le moo, lefu lena le na le tšusumetso e mpe ts'ebetsong ea methapo ea mali le pelo, e tsamaeang le maemo a tsoekere a sa tsitsang, ka lebaka leo nts'etsopele ea maloetse a kotsi a kang:

  • gout
  • ho nyekeloa ke pelo;
  • lefu la pelo;
  • mofuta oa 2 lefu la tsoekere;
  • atherosulinosis;
  • stroke:
  • ischemia;
  • ovary ea polycystic.

Mafu a mangata a beha bophelo ba mokuli kotsing.

Tlhahlobo ea methapo ea mafu

Ho tseba lefu lena ho qala ka ho bokella leseli la mokuli. Mekhoa e metle, mokhoa oa bophelo, ho lemalla bokhobeng, litletlebo le mafu a amanang le ona, linyeoe tsa lefu la tsoekere har'a beng ka motho, sena sohle, hammoho le tlhahlobo ea pono, se tla lumella setsebi ho hlahisa setšoantšo se hlakileng sa boemo ba bophelo ba mokuli.

Etsa bonnete ba hore o lekanya khatello, hlahloba letlalo hore na o na le matšoao a cellulite le a otlollang, ho tseba mokhoa oa ho nona. Mekhoa ea boima bo feteletseng e tla ba data e fumanoeng kamora ho lekanya bophahamo, boima, bophara ba letheka le mpa le boits'oaro ba matšoao ana.

Kahoo, boteng ba botenya bo pakahatsoa ke matšoao a joalo:

  • botenya ba ka mpeng, ka kabo ea mafura ka mpeng, thekeng le molaleng;
  • bophara ba letheka le fetang 88 cm ho basali le 100 cm ho banna;
  • coeff lekaneng ea lethekeng e arotsoe ke bophara ba chi ho feta 1 ho bakuli ba banna le 0,8 ho basali.

Ho etsoa lithuto tse ngata tsa laboratori:

  • mali le moroto oa ho ba teng le boemo ba cholesterol (ka tlase ho 5 mmol / l), triglycerides (ka holimo ho 1.7 mmol / l), lipoprotein tse phahameng le tse tlase tsa "molek" (fetang 6 mm mm / l), tsoekere / ml);
  • sonography le electrocardiography ea pelo;
  • polysomnography;
  • Tlhahlobo ea ultrasound ea tšoelesa ea qoqotho;
  • CT kapa MRI ea gland;
  • CT adrenal gust;
  • ho lekola boemo ba khatello ea mali.

Melao-motheo ea kalafo

Litlhahiso tsa kliniki bakeng sa tlhahlobo ea mafu li ipapisitse le kalafo ea botenya, ho khutlisetsa karabelo ea lisele ho insulin, phokotso ea khatello ea tsoekere le ho tloaela khatello ea maemo.

Ea pele e etsoa ka ho bokella lijo tse reretsoeng ho fokotsa boima ba 'mele le ho eketsa tšebetso ea makoloi. Ho fokotsa ho hanyetsa insulin, kalafo ea lithethefatsi e laetsoe le lithethefatsi tse khothalletsang keketseho ea kutloelo-bohloko ea li-receptor tsa selefounu ho ea ho hormone.

Litokisetso

Phekolo e phethahetseng ea lithethefatsi e kenyelletsa meriana e latelang:

  • Li-inhibitors tsa ACE le lihanyetsi tsa calcium - li fokotsa sekhahla le ho hlapolla methapo ea mali, e thusang khatello ea mali e tlase le ho matlafatsa mesifa ea pelo (Valsartan, Felodipine, Captopril);
  • takatso ea khatello ea maikutlo - ama tsamaiso ea methapo, ho theola maikutlo a tlala (Sibutramine, Fluoxetine);
  • li-inhibitors tse fokotsang ho monya ha mafura - li ama li-enzyme, li fokotsa ho kenella ha lebota la mala (Orlistat, Xenical);
  • li-fibrate le li-statins - lihlahisoa tsa tlase tsa uric acid le ho fokotsa tlhahiso ea cholesterol (Fenofibrate, Lovastatin, Simvastatin);
  • lithethefatsi tse eketsang tšebeliso ea matla (Caffeine, Sibutramine);
  • livithamini - ntlafatsa tsoibilo ea tsoekere mesifa ea skeleton, etsa hore mosebetsi oa sebete o amang, ama cholesterol metabolism (alpha-lipon);
  • lithethefatsi tse khutlisang ho senyeha ha li-hormone - ho ntlafatsa kutloelo-bohloko ea li-receptor tsa cellular, tlhahiso e tlase ea tsoekere bokong (Glucofage);
  • Lithethefatsi tse fokotsang ho loants'oa ha "insulin" - li etsa lintho ka li-receptor tsa cellular, li eketsa ts'ebetso ea lihormone hape li kenya letsoho ho kenya hantle tsoekere maling (Metformin).

Haeba ho hlokahala, ho fanoa ka litlhare tsa pelo (Bisoprolol, Metoprolol).

Khalemelo ea bophelo

Ho kenyelletsa koetliso ea lipapali bophelong ba hau ho ntlafatsa phallo ea mali le ts'ebetso ea pelo, ho thusa ho fokotsa boima ba 'mele le ho matlafatsa mesifa, ho potlakisa le ho khutlisetsa lits'ebetso tsa metabolic, ho eketsa kutloisiso ea li-cellular receptors ho insulin.

Lenane la litlelase e lokela ho ba la kamehla, 'me mefuta ea boikoetliso e khethiloe ho latela lilemo le maemo a bophelo.

Ho molemo ho batho ba tsofetseng le ba nang le mafu a pelo le methapo ea methapo ea pelo ho etsa liteko tse bonolo, ho sesa kapa ho tsamaea maeto a malelele.

Ba banyenyane hape ba phetseng hantle ke ho palama libaesekele, ho matha, ho palama, ho ikoetlisa ka matla, ho fofa le ho tantša.

Liithuti li lokela ho ba monate, 'me li se ke tsa tlisa monate. Ho phahloha ho hoholo hoa ho otla ha pelo le ponahalo ea ho hema hanyane kapa ho tsekela ha li lumelloe. Ho hlophisoa ha litlelase ho bohlokoa. Ho molemo ho qeta hora letsatsi le leng le le leng u ikoetlisa ho e-na le ho khathala ka ho fetesisa hang ka beke.

Ka khatello e phahameng kapa tsoekere, boteng ba liphio kapa lefu la pelo, ts'ebetso e matla ea 'mele e hanyetsanoa. Maemong a joalo, o ka tsamaea butle tseleng ea ho ea sebetsa, ho sesa, ho hloa litepisi tse peli kapa tse tharo ntle le lifti, ho chenchela le ho tjeka mmele, maoto a sisinyehang le boikoetliso bo bong bo bonolo.

Phepo e nepahetseng

Liphetoho tsa phepo ea lijo li lokela ho latela melaoana ea phepo e nepahetseng - lijo tse nang le mafura a mangata le tse nang le lik'habohaedreite.

Lijo tse sa hlokahaleng:

  • paseka, oatmeal, raese e tšoeu, semolina;
  • tsuba limonate, litlolo, soseji le lijo tse ka makotikoting;
  • nama ea duck e mafura, konyana, nama ea kolobe;
  • mafura a liphoofolo (botoro, margarine);
  • li-pastries tse nonneng le lijo tse tsoekere tse nang le tsoekere e ngata (likuku, liswiti, likuku);
  • ketchup, mayonesiise, mosetareta, adjika, meroho e nokiloeng le linoko;
  • li-jusi tse kentsoeng le sirapo e tsoekere;
  • lihlahisoa tsa lebese tse nang le mafura a mangata (curd, tranelate, yogurt e tsoekere, tranelate e bolila ea mafura);
  • litholoana tse monate (morara, morara o omisitsoeng, libanana).

Motheo oa lijo o lokela ho ba:

  • likhoho tsa nama e tlase, tlhapi le nama;
  • lihlahisoa tse felletseng tsa lijo-thollo le li-rye;
  • raese e sootho, li-buckwheat, harese tsa pearl;
  • 1% lihlahisoa tsa lebese le lebese;
  • mahe makhetlo a 2-3 ka beke (mahe a phehiloeng kapa a qhekelloang);
  • soseji habeli ka beke;
  • meroho e mecha le meroho e nang le fiber e ngata, litholoana tse sa fuoeng;
  • meroho le lijo-thollo, meroho e mafura a tlase;
  • k'habeche e bolila;
  • lisosa tse nchafalitsoeng tse ncha le tee e fokolang ntle le tsoekere;
  • chisi e mafura a tlase;
  • chokolete e lefifi, mahe a linotsi, lijo-thollo tsa litholoana tse tsoekere;
  • kvass, compote, jeli, li-decoctions tsa litholoana ntle le tsoekere;
  • lilithara tse peli tsa metsi letsatsi le leng le le leng ke boemo bo bong ba bohlokoa ba metabolism.

Ho fihlela sephetho se tsitsitseng, phepo e joalo e tlameha ho ba tsela ea bophelo. Lithibelo tsa nako e khuts'oane, joalo ka lijo tse nang le li-calories tse fokolang, li tla tlisa phello ea nakoana le ho ama bophelo bo botle.

Lijo tse nang le tlala li sithabetsa 'mele,' me ho haelloa ke liprotheine, liminerale le livithamini ho baka mafu a pelo, a liphio le mala. Lijo tse nang le lik'habohaedreite tse fokotsehileng, ha feela li ka jeoa letsatsi le leng le le leng ho tloha ho 1,500 ho isa ho 2 000 kcal, li tla u lumella ho tlohela butle-butle liponto tse eketsehileng ntle le ho lapa.

Lintho tsa video tse mabapi le lisosa le kalafo ea boemo ba methapo:

Thibelo

Lisosa tse ka sehloohong tsa lefu la metabolic ke ho se ikoetlise 'meleng, liphoso tse fetang boima ba' mele le phepo e nepahetseng.

Ho fokotsa kotsi ea boemo bo amanang le ts'oaetso ea methapo, o hloka feela ho qhelela likotsi tsena:

  1. Fokotsa palo ea lijo tse ka fokotsang takatso ea hau ea lijo. E kanna ea ba meroho e chesang le lisose, li-seasonings le linoko (mosetareta, konofolo, pereeradish, adjika, pepere e ntšo le e khubelu).
  2. Se ke oa etsa nako e telele pakeng tsa lijo. Boikutlo bo sa feleng ba tlala bo lebisa ntlheng ea hore ho ja lijo tse ngata.
  3. Se ke oa ja pele u robala. Ka toro, metabolism e ea fokotseha 'me lijo ha li anngoe hantle, e leng se arabelang ho boima bo ka mpeng le mafura a mangata ka mpeng.
  4. Fokotsa litšebeletso. Palo e kholo ea lijo tse jetsoeng hang, e otlolla mala mme e baka ho thunya le botenya.
  5. Qoba lijo tsa hang-hang le lijo tse potlakileng. Lijo tsena hangata li na le lik'hilojule tse ngata ebile li na le mafura a mangata le lik'habohaedreite.
  6. Qoba ho tsuba le ho lemalla joala. Alcohol ke caloric mme e tsosa takatso ea lijo, ha nicotine e baka vasospasm mme e sitisa phallo ea mali.
  7. E-ea bakeng sa lipapali. Ingoliso sehlopheng sa boikoetliso ba 'mele, ho sesa, ho tsamaea, ho ikoetlisa lapeng. Mofuta o mong le o mong oa ho tsamaea o sebetsang o tla ntlafatsa ho potoloha ha mali, o potlakise metabolism le ho thibela botenya.
  8. Ho etela ho hlapela kapa ho ba le linako tsa ho ikoetlisa ho tla potlakisa ho phatloha ha mafura a mangata.
  9. Ho etsa tlhahlobo ea bongaka ea selemo le selemo. Sena se tla thusa ho lemoha nts'etsopele ea mafu le ho laola boemo ba tsoekere le cholesterol.

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