Li-Macrolides le penicillin ke a mang a lihlopha tse sireletsehileng ka ho fetisisa tse sebetsang hantle tsa meriana e thibelang likokoana-hloko. Li sebelisetsoa ho phekola tšoaetso ea litho tsa ka hare, lisele tse bonolo le letlalo. Ho latela lipontšo tsa ts'ebeliso le moemeli oa lefu lena, ngaka e ka beha Klacid kapa Amoxiclav, le lithethefatsi tse tšoanang ka sebopeho le phello ho tsona (Clarithromycin, Augmentin, Sumamed).
Tšobotsi ea Klacid
Karolo e sebetsang ea Klacid ke mofuta oa macrolide o thibelang likokoana-hloko. Ponahalo ea ts'ebetso ea eona ea antibacterial e fetela ho likokoana-hloko tse tloaelehileng tsa mafu a tšoaetsanoang. Likokoana-hloko tse nahanelang li kenyelletsa:
- libaktheria tsa aerobic tsa gram-positive le gram-negative aerobic (streptococci, pneumococci, moraxella, hemophilus bacillus, listeria, jj);
- likokoana-hloko tsa anaerobic (clostridia, jj);
- li-agent tsa causative tsa li-STD (chlamydia, mycoplasma, ureaplasma);
- toxoplasma;
- Borrelia
- Helicobacter pylori (H. pylori);
- mycobacteria (ha e bontše katleho e lekaneng hafeela e ts'oaetsoa ke lefuba microbacteria).
Klacid le Amoxiclav ba sebelisoa ho phekola tšoaetso ea litho tsa ka hare, lisele tse bonolo le letlalo.
Ts'ebetso e fapaneng ea ts'ebetso eacacithromycin e u lumella ho beha Klacid ka lipontšo tse latelang:
- tšoaetso ea baktheria ea likarolo tse kaholimo le tse tlase tsa sesebelisoa sa ho hema (sinusitis, tonsillitis, pharyngitis, media media, tracheobronchitis, pneumonia ea atypical, jj.);
- folliculitis, erysipelas, lisele tse ling tsa baktheria tsa letlalo le lisele tse poteletseng;
- mafu a lehae le a tsamaiso a bakoang ke mycobacteria (ntle le Koch's bacillus);
- prophylaxis ea ts'oaetso ea mycobacterial e halefisitsoeng ke M. avium ho bakuli ba nang le tšoaetso ea HIV ba nang le litaba tse tlase tsa bathusi ba T;
- seso sa ka mpeng le seso sa duodenal (molemong oa ho fokotsa khatello ea mali ea H. pylori e le karolo ea thupelo ea antibacterial e kopaneng);
- Mafu a likobo a bakoang ke likokoana-hloko tse anngoeng ke clearithromycin;
- thibelo ea mathata a baktheria kamora lits'ebetso tsa meno (ho kenyelletsa sepsis le endocarditis).
Ho ipapisitsoe le bokuli le lilemo tsa mokuli, ngaka e ka u fa mofuta o latelang oa ho lokolloa ha Klacid:
- matlapa (litekanyetso tsa motsoako o sebetsang - 250 le 500 mg);
- ho emisoa (palo ea lithibela-mafu ka ho 5 ml ea sehlahisoa se felileng ke 125 kapa 250 mg);
- phofo bakeng sa ho hlophisoa ha tharollo ea infusion (lethal dose la clarithromycin - 500 mg ka botlolong e le 'ngoe).
Karolo e sebetsang ea Klacid ke mofuta oa macrolide o thibelang likokoana-hloko.
Klacid ha e khethoe ka mokhoa oa liente: Tsamaiso ea methapo ea methapo ea kutlo ea macrolide e etsoa hora kapa nako e teletsana.
Contraindication mabapi le tšebeliso eacacithromycin ke:
- hypersensitivity ho lithethefatsi tsa macrolide le ketolide, metsoako e thusang ea lithethefatsi;
- ho nyekeloa ke pelo, lefu la pelo, corricary arrhythmia le tachycardia, ho ba teng hoa lintlha tsa proarrhythmogenic le kotsi e eketsehang ea ho lelefatsa nako ea QT (mohlala, khaello e matla ea potasiamo le magnesium);
- motsoako oa ho hloleha ha liphio le sebete;
- cholestatic jaundice, e halefisitsoeng ke ts'ebeliso ea antibiotic ena (nalane);
- lebone
- ho ima (ho trimester ea 2-3, hoa khoneha ho sebelisa ho latela matšoao a thata);
- dilemo tse ka tlase ho likhoeli tse 6;
- lefu la porphyrin;
- kalafo e nang le lithethefatsi e lumellanang lecacithromycin (Ergotamine, Colchicine, Ticagrelor, Midazolam, Ranolazine, Cisapride, Astemizole, Terfenadine, li-statins, jj.).
Tabeng ea ts'ebetso ea ho senyeha ha sebete le liphio (haeba Cl creatinine e sa nyane ho feta e tloaelehileng, empa e feta 30 ml / min), kalafo ea clearithromycin e lokela ho etsoa ka tlhatlhobo ea bongaka le ho hlahloba biochemistry ea mali. Ha u fana ka taelo ea ho emisoa ha Klacid ho bakuli ba nang le lefu la tsoekere, ho lokela ho nahanoa tekanyo ea ho lekana ka tekanyetso ea moriana o khothalletsoang.
Ha u fana ka taelo ea ho emisoa ha Klacid ho bakuli ba nang le lefu la tsoekere, ho lokela ho nahanoa tekanyo ea ho lekana ka tekanyetso ea moriana o khothalletsoang.
Litšobotsi tsa Amoxiclav
Amoxiclav e na le motsoako oa antibacterial (amoxicillin) le beta-lactamase inhibitor (clavulanic acid). Clavulanic acid e thibela ts'ebetso ea li-enzyme tsa baktheria tse felisang mohala oa lithibela-mafu tsa beta-lactam. Ho kopana ha likarolo tsena tse peli ho u lumella ho nka khato ho kenyelletsa le likokoana-hloko tse loantšang penicillin e sa sirelitsoeng.
Kakaretso ea ts'ebetso ea amoxicillin e fetela ho likokoana-hloko tse latelang:
- likokoana-hloko tsa gram tse ntle tsa aerobic (staphylococci, streptococci, pneumococci);
- gram-negative aerobic cocci (hemophilic le Escherichia coli, moraxella, Klebsiella, enterobacteria).
Matšoao a ts'ebeliso ea lithethefatsi ke mekhoa e latelang:
- tšoaetso ea baktheria ea phepelo ea phefumoloho e kaholimo le e ka tlase;
- ts'ebetso ea ho ruruha ea mochine oa moroto o bakoang ke likokoana-hloko tsa aerobic;
- mafu a ka mpeng: (gastric le ulodenal ulcers, ho ruruha ha gallbladder le bile ducts);
- mafu a tšoaetsanoang a mokhoa oa ho ikatisa;
- tšoaetso ea odontogenic, thibelo ea mathata a baktheria kamora ts'ebetso ea meno;
- osteomyelitis, lefu la methapo e amehang;
- lisele tsa baktheria tsa letlalo le lisele tsa subcutaneous;
- bakeng sa tsamaiso e kenelletseng ea Amoxiclav: STD (gonorrhea, chancre e bonolo), ho kenella ka mpeng ka mpeng, ho thibela mathata a tšoaetsanoang ka mor'a ho buuoa.
Amoxiclav e fumaneha ka mefuta e 'maloa ea litekanyetso:
- matlapa (litekanyetso tsa amidillin ke 250, 500 kapa 875 mg);
- matlapa a qhekellang (a qhibilihang) (a na le 500 kapa 875 mg ea lithibela-mafu);
- lyophilisate bakeng sa tlhahiso ea methapo e kenang (lethalosa la motsoako oa antibacterial ka botlolong e le 'ngoe ea lyophilisate ke 500 mg kapa 1 g);
- phofo bakeng sa tlhahiso ea ho emisoa (5 ml ea moriana o felileng o na le 125, 250 kapa 400 mg ea ntho e sebetsang, ho latela tekanyetso e boletsoeng).
Amoxiclav e na le motsoako oa antibacterial (amoxicillin) le beta-lactamase inhibitor (clavulanic acid).
Contraindranation mabapi le ho nka Amoxiclav ke li-pathologies tse kang:
- hypersensitivity ho lithethefatsi tsa lihlopha tsa penicillin le cephalosporin, hammoho le monobactam le carbapenem;
- litla-morao le mathata a metabolic a likarolo tse ling tsa Amoxiclav (phenylketonuria);
- "litšoelesa" tsa "monocytic" tsa "tonsillitis";
- lymphocytic leukemia;
- ts'ebetso e senyehileng ea hepatic ka lebaka la kalafo ea amoxicillin (nalane);
- ha o fana ka matlapa a qhekellang Amoxiclav: boima bo ka tlase ho 40 kg, lilemo tsa bana (ho fihlela lilemo tse 12), ho se sebetse hantle ha a ramatiki (Cl creatinine <30 ml / min.).
Ka hlokolosi, Amoxiclav e laetsoa methapo ea sebete le ea liphio, kalafo ka li-anticoagulants, bakeng sa nalane ea mafu a ka mpeng a bakoang ke kalafo ea antibacterial, bakeng sa lactation le moimana.
Papiso ea Klacid le Amoxiclav
Matšoao a ho khethoa ha Amoxiclav le Klacid lia tšoana. Khafetsa e fapaneng ea tšebeliso e bakoa ke phapang ea bongata ba ts'ebetso ea antibacterial, litšenyehelo le polokeho ea lithethefatsi.
E tšoanang
Litšobotsi tse tšoanang ho lithethefatsi tsena ka bobeli ke:
- Ketso e fapaneng ea antibacterial.
- Nako e khothalletsoang ea kalafo (matsatsi a 5-14) le khafetsa ho nka li-antibacteric (makhetlo a 2 ka letsatsi).
- Boemo ba ho tlohela ho tloha litlolong tsa litlhare (litlhare).
- Ho sebetsa hantle khahlanong le libaktheria tse hlahisang beta-lactamases.
- Ho kenella kalafong e rarahaneng ea liso tsa ka mpeng tse halefisitsoeng ke H. pylori.
Phapang ke efe?
Phapang pakeng tsa Klacid le Amoxiclav e bohlokoa le ho feta. Phapang ea lithethefatsi e bonoa likarolong tse kang:
- Sehlopha sa Tšireletso sa FDA. Amoxicillin e ratoa haholo hore e sebelisoe ke basali baimana.
- Monyetla oa tšebeliso nakong ea lebone. Amoxiclav e lumelloa ho sebelisoa bakeng sa matsoele, 'me Klacid ha e khothalletsoe.
- Bonyane lilemo tse tlase moo moriana o ka sebelisoang. Lisebelisoa tse thehiloeng ho Amoxicillin li ka fuoa bana ho tloha matsatsing a pele a bophelo. Klacid o fuoe masea a kaholimo ho likhoeli tse tšeletseng.
- Motsoako oa letsatsi le letsatsi oa lithibela-mafu. Ha e phekoloa le Amoxiclav, ke 750-1750 mg, le Klacid - 500-1000 mg.
- Liphetoho tse fapaneng le li-contraindication. Clacid e tšoauoa ka litlamorao khafetsa ho tsoa ho tsamaiso ea methapo e kholo (ho senyeha ha kutlo le ho nkha, ho hloka boroko, hlooho e bohloko).
E leng theko e tlase
Ka nako e tšoanang ea phekolo, Klacid e tla bitsa makhetlo a 2-3 ho feta Amoxiclav. Karolelano ea litjeo tsa thupelo ea kalafo e latela mofuta oa kalafo ea lithibela-mafu.
Se leng betere: Klacid kapa Amoxiclav
Khetho ea lithethefatsi e etsoa ke ngaka ho latela tlhahlobo ea mokuli, mofuta oa moemeli ea tšoaetsanoang le nalane ea bongaka.
Amoxiclav e nkoa e le lithethefatsi tsa khetho kalafong ea tšoaetso ea ts'oaetso ea phefumoloho e bakoang ke likokoana-hloko tse tloaelehileng. Ho bolokehile bakeng sa lihlopha tse hlaselehang habonolo tsa bakuli.
Hangata Klacid e laeloa ho bakuli ba baholo ba nang le mafu a likobo, ts'oaetso e matla ea methapo le ea lehae.
Tlhahlobo ea Mamello
Maria, ea lilemo li 31, Astrakhan
Hangata ngoana o na le mathata ka 'metso (tonsillitis, pharyngitis). Pejana, ngaka e ne e laetse Amoxicillin le analogues ea eona, empa lekhetlong lena meriana e thibelang likokoana-hloko ha e a thusa, le eona ha ea ka ea theola mocheso. Kamora matsatsi a 3 a bokuli, moriana o ile oa fetoloa hore ebe Klacid. E se e le ka letsatsi la bobeli la kamohelo, mocheso o ile oa theoha haholo, mme ngoana a qala ho fola.
Ke khotsofetse ke sephetho, empa lithethefatsi li na le litlamorao tse matla - ho nyekeloa hoa pelo.
Olga, ea lilemo li 28, Krasnodar
Amoxiclav ke sebapali se pharaletseng se sebetsanang le mosebetsi oa sona hantle. Setlhare sena se ne se laetsoe bokuli ba mora oa hae, ha a ne a le selemo feela. Ngoana o ne a thabetse ho noa moriana ka mokhoa oa ho emisoa, mme kamora matsatsi a 1-2 sephetho se ne se se se bonahala.
Setlhare sena se boetse se loketse batho ba baholo, ka hona ho bohlokoa ho boloka matlapa le phofo ka khabineng ea litlhare tsa lapeng.
Lingaka li hlahloba ka Klacid le Amoxiclav
Bakieva E.B., Ngaka ea meno, Ufa
Klacid ke lithethefatsi tse ntle, tse sebetsang tse tsoang ho moetsi oa Jeremane. E ea sebetsa khahlano le mefuta e mengata ea libaktheria tse hananang le lithibela-mafu tsa setso. E na le tropism e phahameng bakeng sa lisele tsa masapo le meno, ka hona e sebelisoa ka mafolofolo ho tsa bongaka le ho buuoa.
Ke fana ka moriana ona ho bakuli ba nang le osteomyelitis, periostitis, odontogenic sinusitis le mafu a mantlha a baktheria ea tsamaiso ea matšoafo (tonsillitis, pharyngitis).
Ntho e ka mo sitisang ke ho arabela khafetsa khafetsa ka mpeng.
Almasri A.M., gastroenterologist, Moscow
Amoxiclav hangata e laeloa mafu a ho phefumoloha, empa sethethefatsi se fana ka liphetoho tse matla maemong a mang (mohlala, ka ulcers, cholecystitis, jj). Moriana e thibelang likokoana-hloko e fumaneha ka mefuta e mengata, 'me ho bonolo ho e sebelisa. Monyetla o mong ke theko e theko e tlaase.
Nakong ea kalafo, mathata a mokokotlo a ka etsahala, 'me hangata candidiasis e ba teng ka mor'a taolo.
