K'holeseterole e phahamisitsoeng e kenya letsoho kholisong ea methapo ea pelo le pelo. Ho latela lipalo-palo, mafu a joalo khafetsa ho feta a mang a baka ho otloa kapa ho otloa ke pelo.
Ho bokelloa ha cholesterol e mpe maling ho hlahisoa ke ho se sebetse hantle ha metabolism ea lipid. Lisosa tse ling tsa hypercholesterolemia ha lia itšetleha ka motho (lefutso). Empa khafetsa lefu lena le hlaha khafetsa ka lebaka la mokhoa o fosahetseng oa ho phela - ts'ebeliso e mpe ea lijo tse kotsi, tse mafura, ho tsuba, joala, ho hloka mesebetsi ea 'mele.
Hypercholesterolemia e bonolo kapa e itekanetseng e phekoloa ka katleho kalafo ea phepo. Empa mofuta o hlokomolohileng oa lefu lena o hloka tšebeliso ea meriana.
Ursosan hangata e sebelisoa ho theola cholesterol. Empa pele u sebelisa lithethefatsi, o lokela ho ithuta haholoanyane ka likarolo tsa eona.
Sokolla foromo le sebopeho
Ursosan ke oa sehlopha sa hepatoprotectors. E entsoe ka mokhoa oa li-capsules tsa mnara tsa gelatin tse tlatsitsoeng ka phofo e hatelletsoeng.
Ka har'a sephutheloana se le seng e ka ba 10,50 le li-capsules tse 100. Motsoako ona o hlahisoa ke k'hamphani ea meriana ea mafu a meriana PR.MED.CS Praha, a.s.
Ntho e sebetsang ea lithethefatsi ke ursodeoxycholic acid. Bokaholimo bo le bong bo na le 0,25 g kapa 0,50 g ea motsoako o sebetsang.
Likarolo tse ling:
- tekanyetso ea titanium;
- gelatin;
- colloidal titanium dioxide;
- letsoai la magnesium la stearic acid;
- starch ea poone.
Melemo ea pharmacological le molao-motheo oa ketso
Ka mafu a hepatobiliary, membrane le mitochondria ea lisele tsa sebete li senyehile. Sena se lebisa ho arohaneng ha metabolism ea bona, ho fokotseha tlhahiso ea li-enzyme le thibelo ea bokhoni ba ho inchafatsa.
Ursodechoxycholic acid e kopana le phospholipids, ka lebaka leo mefuta e rarahaneng ea limolek'hule e bang karolo ea marako a sele ea sebete, mala, le ducts tsa bile. Hape, metsoako e thehiloeng e eketsa ts'ireletso ea cytoprotective, e lekanya phello ea li-acid tse nang le chefo.
Sena se lebisa liphellong tse 'maloa tse ntle tse bang teng ka har'a sebete. Ka hona, thepa ea antitoxic ea setho e eketseha, kholo ea mesifa ea "fibrous" e ea theoha, phapang e ea fetoha, 'me potoloho ea lisele e ea tsitsa.
Lihlahisoa tse ling tsa pharmacological tsa Ursosan:
- E fokotsa ho kenngoa ha li-acid acid ka har'a mucosa ea tšilo ea lijo. Sena se eketsa tlhahiso le secretion ea bile, e thusa ho hatella thepa ea lithogenic ea bile le ho fokotsa khatello maemong a biliary.
- E thibela synthet ea k'holeseterole ka hepatocytes, e lebisang ho fokotseha ha khatello ea lipid. Ursodeoxycholic acid e senya cholesterol le ho fokotsa bilirubin ho bile.
- E eketsa tlhahiso ea li-enzymes tsa pancreatic, tse u lumellang ho etsa hore litho tsa kahare tse jang 'mele li fetole le ho fokotsa tsoekere e ngata.
Ursosan e na le phello e molemo tsamaisong ea 'mele ea ho itšireletsa mafung. Phello e ts'oanang e fumanoa ka ho thibela li-immunoglobulins, ho fokotsa mojaro oa li-antigenic ducts tsa bile, lisele tsa sebete, ho hatella ts'ebetso ea eosinophilic le ho eketsa sebopeho sa cytokines.
Ursosan e kenella kahare ho mucosa ea tsamaiso ea tšilo ea lijo. E amana le liprotheine tsa plasma ka 97%.
Kamora ho sebelisa Ursosan, khatello e phahameng ka ho fetisisa ea motsoako o moholo maling e fumanoa ka mor'a lihora tse 1-3. Metabolism ea eona e ba teng ka har'a sebete, ka lebaka leo ho thehoa li-glycine le taurine conjugates, tse epolotsoeng bile.
Ho fihlela 70% ea ursodeoxycholic acid e epiloe ka har'a lero.
Masala a arotsoe ka har'a tšilo ea lijo hore lithocholic acid li fetisetsoe ka har'a sebete. Moo, e sirapo, ebe e ntšoa ka har'a bile.
Matšoao le contraindication
Ursosan e sebelisoa bakeng sa hepatitis A, C le B. E fuoe lefu la lefu la nyooko, ho taha joala, cirrhosis.
Sesebelisoa se sebelisoa maemong a dyskinesia le intrauterine anomaly ea bile duct. Ka thuso ea Ursosan, cholangitis, cystic fibrosis, Reflux esophagitis kapa gastritis li phekoloa ka katleho.
Setlhare sena se sebelisetsoa ho se sebetse hantle hantle ka mpeng mochini o silafalitsoeng ke pherekano. Setlhare sena se sebelisetsoa ho fokotsa litlamorao tse mpe sebeteng kamora ho nka lithibela-mafu, lithethefatsi tse khahlanong le mofets'e, lithibela-pelehi tsa molomo. Ursosan e boetse e laeloa ho jaundice ho masea le hepatosis.
Empa na Ursosan cholesterol e tlase ea mali? Tlhahlobo ea lingaka tse ngata e bonts'a hore moriana o ka fokotsa palo ea lipoprotein tse tlase maling. Hypocholesterolemic effect e fihlelleha ka ho thibela tlhahiso ea cholesterol 'meleng, e fokotsa ho tsoa ha eona ka har'a bile e sitise ho kenngoa ha eona ka ka popelong.
Ursosan e ka fokotsa le monyetla oa ho ba le ponahalo ea letheba la atherosselotic. Hape, hepatoprotector e khona ho tlosa mafura liseleng tsa sebete. Ka hona, e laeloa bakeng sa botenya bo bakoang ke ho bokellana ha cholesterol ke hepatocytes.
Ursodeoxycholic acid e ka eketsa phello ea kalafo ea li-agents tse ling tse nang le phello ea anticholesterolemic. Maemong ana, ntho e sireletsa liseleng liphellong tse mpe tsa meriana.
Ursosan e mamelloa hantle ke 'mele, empa maemong a' maloa ts'ebeliso ea eona e hanana. Lithethefatsi ha li fanoe maemong a latelang:
- boteng ba li-fistulas tsa biliary;
- ho se sebetse hantle ha liphio le sebete;
- ho mpefatsa ha mafu a sistimi ea hepatobiliary;
- ho fokotseha ha ts'ebetso ea gallbladder;
- ho hloka mamello ho likarolo tsa sehlahisoa;
- blockage ea bile duct;
- ho ba teng hoa sistimi ea urogenital ea majoe a nang le calcium;
- cirrhosis e fokotsitsoeng;
- tsamaiso ea tšilo ea lijo
- lilemo ho isa ho lilemo tse 4.
Tlolo ea molao mabapi le ho nka Ursosan ke ho ima. Empa ha ho hlokahala, ngaka e ka u fa moriana o nang le moriana o mong oa marang-rang oa 2-3.
Litaelo tsa tšebeliso ea lithethefatsi
Ursosan o nkuoa ka molomo ntle le ho hlafuna botlolo.
Li hlatsoa metsi a mangata.
Ho khothalletsoa ho noa moriana mantsiboea.
Tekanyetso le nako ea phekolo e tla khethoa ke botebo le mofuta oa lefu lena. Hangata moriana o nooa ho tloha likhoeli tse 6 ho isa ho lilemo tse peli.
Ka karolelano, bongata ba lithethefatsi li khethoa ho latela boima ba mokuli:
- ho fihlela ho 60 kg - likhabapo tse 2 ka letsatsi;
- 60-80 kg - matlapa a 3 ka letsatsi;
- 80-100 kg - li-capsules tse 4 ka letsatsi;
- ho feta 100 - li-capsules tse 5 ka letsatsi.
Ha Ursosan e laetsoe molemong oa ho qhala majoe a cholesterol, boemo ba bohlokoa ke hore majoe a be X-ray a nang le bophara ba limilimithara tse 20. Maemong ana, gallbladder e lokela ho sebetsa ka tsela e tloaelehileng, 'me ho ke ke ha khoneha hore palo ea majoe ho eona e feta halofo ea palo ea litho tsa setho.
Hape, bakeng sa resorption ea gallstones, ho hlokahala hore li-ducts tsa bile li be le patency e ntle. Kamora ho qhala majoe a cholesterol, ho hlokahala hore u noe Ursosan matsatsi a mang a 90 e le mokhoa oa ho thibela pelehi. Sena se o lumella ho hlakola masala a majoe a khale le ho thibela sebopeho sa majoe a macha.
Pele o nka Ursosan e le hore a fokotse cholesterol e phahameng, ho kgothaletswa ho nka liteko bakeng sa AST, ALT le ho etsa lipatlisiso ho fumana hore na cholesterol e kae maling. Liphetho tsa liteko li bapisoa pele le kamora kalafo, e lumellang ngaka ho utloisisa hore na Ursosan e thusitse k'holeseterole e kae.
Hoa hlokomeleha hore ho bakuli ba sa tšoaroeng ke hypercholesterolemia le atherosclerosis, kamora ho nka hepatoprotector, palo ea cholesterol 'meleng e ka fokola ho feta e tloaelehileng.
Leha ho le joalo, boemo bona ha bo kotsi ho bophelo bo botle mme qetellong ea kalafo ea feta.
Litla-morao le ho sebelisa overdose haholo
Khafetsa, ho ba le maikutlo a fosahetseng ka mor'a ho nka Ursosan ho etsahala ho bakuli ba sa lateleng litaelo tsa bongaka. Lintho tse ngata tse sa thabiseng li amana le ho sitisoa ha tšilo ea lijo. Ho hlatsa hona, ho nyekeloa hoa pelo, khase e eketsehileng, bohloko ba ka mpeng le ho senyeha hoa mala ka mpeng (ho sokela kapa lets'ollo).
Ho sebelisoa ha Ursosan nako e telele ho ka etsa hore majoe a cholesterol a sebetse. Phekolo ea Hepatoprotective ka linako tse ling e kenya letsoho ho nts'etsopele ea maloetse 'me e lebisa ho hlobaeleng, bohloko ba morao, alopecia, baldness, exacerbation ea psoriasis.
Haeba ho na le overdose ea Ursosan, lets'ollo hangata le hlaha, litla-morao tse sa thabiseng li hlaha ha tekanyetso e fetisoa. Maemong ana, ntho e sebetsang ea lithethefatsi e qala ho kenella ka mpeng ea mala mme e siea 'mele hammoho le mantle.
Haeba lefu la makhopho le bonoa kamora ho nka Ursosan, ho lokela ho nkuoa mehato e latelang:
- fokotsa litekanyetso tsa lithethefatsi kapa u tlohele ho li sebelisa ka botlalo;
- nwa metsi a mangata a hloekileng;
- khutlisetsa chelete ea electrolyte.
Tšebelisano ea lithethefatsi le li-Analog
Taeo ea lithethefatsi e re Ursosan e ke ke ea kopanngoa le aluminium le li-antacid tse nang le lits'oants'o tsa phapanyetsano ea ion. Sena se ka fokotsa ho monya ha ursodeoxycholic acid.
Ts'ebetso e le 'ngoe ea lithethefatsi ka li-estrogens, Neomycyon, clofibrate le Progestin li tla lebisa ho eketseha ha cholesterol' meleng. Ts'ebeliso ea Ursosan e nang le k'holeseterole le cholestyramine, e leng bahanyetsi le eona ha e ratehe.
Hepatoprotector e ntlafatsa phello ea Razuvastatin, ka hona, litekanyetso tsa morao-rao li lokela ho fokotsoa. Ursosan e theola katleho ea kalafo ea litlhare tse latelang:
- Dapson;
- Li-cyclosporins;
- Nifedipine;
- Nitrendipine;
- Baprofloxacin.
Nakong ea kalafo le Ursosan, ho ke ke ho sa ratehe ho noa joala le tinctures ka ethanol. Ho khothalletsoa hape ho latela nomoro ea 5 ea lijo, ntle le tšebeliso ea lijo tse mafura, nama e tsubelloang, lijo tse ka makotikoting le lino tse tahiloeng.
Litšenyehelo tsa Ursosan bakeng sa li-capsules tse 10 (250 mg) - ho tloha li-ruble tse 180, li-capsules tse 50 - ho tloha li-ruble tse 750, li-capsules tse 100 - ho tloha ho li-ruble tse 1370. Haeba letlapa le le leng le na le 500 mg ea ntho e sebetsang, joale theko ea lithethefatsi e eketseha (likotoana tse 50 - 1880 p., Likotoana tse 100 - 3400 p.).
Litšoantšo tse tummeng tsa Ursosan ke Aeshol, Ursokhol, Livodeksa, Holudexan, Ursofalk, Urso 100 le Ursomax. Hape, lithethefatsi li ka nkeloa sebaka ke mekhoa e kang Grinterol, Ursacline, Ursodez, Allohol le Ursofalk.
Litlhahlobo mabapi le Ursosan li ntle haholo. Bakuli ba hlokomela hore moriana o hlile o qhibilihisa majoe mme o thibela sebopeho sa ona se tlang. Leha ho le joalo, phello ea kalafo e fihlella bonyane likhoeli tse 3 kamora ho qala ha moriana.
Ursosan e na le litlhahlobo tse mpe. Khafetsa li amahanngoa le ntlafatso ea litla-morao tse kang setuloana se matla le ho nyekeloa hoa pelo. Empa leha ho le joalo, lingaka le bakuli ha ba hane tšebetso e phahameng ea lithethefatsi kalafong ea mafu a gallstone le hypercholesterolemia.
Tlhahlobo ea Ursosan e fanoa ka video videong ena.
