Steroid lefu la tsoekere ke lefu le bakoang ke ho se sebetse hantle ha adrenal cortex kapa tšebeliso e telele ea lithethefatsi tsa lihormone.
Kotsi e kholo ea lefu la tsoekere la steroid ke ho batho ba reriloeng hore ba na le lefu la tsoekere, re tla tseba hore na ke eng, hore na hypercorticism e amanang le boemo bona, le hore na ba lokela ho etsa eng.
Boloetse bona bo na le phello e mpe makhophong, bo senya lisele tsa mmele le ho sitisa tlhahiso e tloaelehileng ea insulin. Ka lebaka lena, lefu la tsoekere la steroid hangata le bitsoa mofuta oa 1 oa lefu la tsoekere.
Mabaka
Ho na le mabaka a mabeli a bohlokoa a nts'etsopele ea lefu la tsoekere la steroid:
Joaloka motsoako oa maloetse a qholotsang tlhahiso ea lihormone tsa adrenal cortex, mohlala, lefu la Itsenko-Cushing;
Ka lebaka la kalafo ea nako e telele le lithethefatsi tsa lihormone.
Hangata, lebaka la ponahalo ea lefu la tsoekere la steroid ke tšebeliso ea lithethefatsi tsa lihormone, ke ka lebaka leo ka linako tse ling li bitsoang lefu la tsoekere la lithethefatsi. Lefu lena le kotsi le lula le e-ba le litlamorao tse mpe ka kalafo ea nako e telele le lithethefatsi tsa glucocorticoid tse kang:
- Hydrocortisone;
- Prednisone;
- Dexamethasone.
Hangata lithethefatsi tsena li laetsoe ho loants'oa ts'oaetso ea mafu a mafu a sa foleng le bakeng sa kalafo ea methapo ea methapo. Ka hona, lefu la tsoekere la steroid hangata le ama bakuli ba nang le mafu a latelang:
- Lerotholi la bronchial;
- Rheumatoid ramatiki;
- Maloetse a fapaneng a autoimmune (pemphigus, eczema, lupus erythematosus);
- Multiple sclerosis.
Ntle le moo, tšebeliso ea li-diuretics tse itseng li ka ama nts'etsopele ea lefu la tsoekere la steroid. Tse tummeng har'a tsona ke lisebelisoa tse latelang:
- Dichlothiazide;
- Hypothiazide;
- Nephrix
- Navidrex.
Hape, mofuta ona oa lefu la tsoekere o fumanoa hangata ho basali ba sebelisitseng lithibela-pelehi tsa lihormone nako e telele ho li sireletsa khahlanong le boimana bo sa batleheng.
Ntle le moo, batho ba kileng ba etsa opereishene ea ho tsamaisa meno le bona ba kotsing.
Matšoao
Ho fumana hore na li-steroid le lefu la tsoekere li amana joang, u hloka ho utloisisa hore na lithethefatsi tsa lihormone li sebetsa joang 'meleng oa motho. Ka tšebeliso ea nako e telele ea chelete ena ho mokuli, biochemistry ea mali e fetoha haholo. Tabeng ena, boemo ba corticosteroids ho eona bo eketseha haholo.
Li-Steroid li ama hampe li-cell tsa "pancreatic b", tse lebisang ho necrosis ea tsona ea butle-butle. Sena se ama boemo ba insulin ea 'mele' meleng oa mokuli, bo fokotsa bonyane le ho hlohlelletsa kholo ea lefu la tsoekere. Ho feta moo, lihormone tsa steroid li etsa hore lisele tsa 'mele li se ke tsa tšoaroa ke insulin, tse sitisang metabolism ea carbohydrate.
Kahoo, matšoao a lefu la tsoekere la mofuta oa 1 le mofuta oa 2 ke tšobotsi ea lefu la tsoekere la steroid. Ka lebaka leo, lefu lena le ka ba matla haholo mme la baka mathata a tebileng.
Ho lokela ho hopoloa hore lefu la tsoekere, le halefisitsoeng ke li-steroid, le hlaha butle butle mme maemong a pele a lefu lena ha le khone ho iponahatsa. Matšoao a latelang a bontša ho ba teng ha lefu la tsoekere la sethoathoa ho motho:
- Lenyora le leholo. Ho mo khotsofatsa, mokuli o ja metsi a mangata;
- Mokhathala le ts'ebetso e fokotsehileng. Ho ba thata hore motho a phethe mesebetsi e tloaelehileng ea letsatsi le letsatsi;
- Khafetsa ho ntša. Ka ketelo e 'ngoe le e' ngoe ea ntloaneng, moroto o mongata o abeloa mokuli;
Ho feta moo, ho fapana le lefu la tsoekere la mofuta oa 2 le ho bakuli ba nang le mofuta oa lefu lena la steroid, boemo ba tsoekere maling le moroto ha bo fetelle ka tloaelo. Hoa tšoana le maemong a acetone, eo hangata e sa feteng ka mokhoa o lumelloang. Sena se tiisa mathata a lefu lena.
Lintho tse kenyang letsoho ho nts'etsopele ea lefu la tsoekere la steroid:
- Phekolo ea nako e telele le corticosteroids;
- Ho ja khafetsa lithethefatsi tsa li-hormonal ho tekanyetso e phahameng;
- Keketseho khafetsa ea tsoekere ea mali ka mabaka a sa tsejoeng;
- Boima bo bongata haholo.
Ho bohlokoa ho totobatsa hore bakuli ba bangata ba sebelisang lithethefatsi tsa lihormone ba ka ba le lefu la tsoekere. Leha ho le joalo, hangata e tsoela pele ka mokhoa o bonolo ebe e nyamela ka botlalo kamora ho qeta kalafo.
Mokhoa o matla oa lefu lena, e le molao, o bonoa feela bathong ba nang le lefu la tsoekere kapa ba seng ba ntse ba tšoeroe ke lefu lena. Batho ba bangata ba nang le lefu la tsoekere ha ba tsebe ka lefu la bona, ha lefu lena le ntse le tsoela pele. Leha ho le joalo, ho nka corticosteroids ho ntlafatsa tsela ea lefu lena le ho potlakisa kholo ea lona.
Ntho e 'ngoe e tlatsetsang ho hlaha ha lefu la tsoekere la steroid ke boima bo fetisisang, bo paka hore lefu la tsoekere le botenya li kopane.
Batho ba nang le bothata ba botenya ba lokela ho nka meriana ea lihormone ka hloko e kholo ha feela ho na le khothatso ea ngaka bakeng sa sena.
Phekolo
Phekolo ea lefu la tsoekere la steroid e lokela ho etsoa ho latela sethala sa lefu lena. Haeba secretion ea insulin 'meleng e ne e emisitsoe ka botlalo, joale ntoa khahlanong le lefu lena e lokela ho etsoa ka tsela e ts'oanang le lefu la tsoekere la mofuta oa 1.
Phekolo ea lefu la tsoekere e itšetlehileng ka insulin e kenyelletsa mekhoa e latelang:
- Liente tsa insulin tsa letsatsi le letsatsi;
- Ho tsamaellana le phepo e nepahetseng (hona e kanna ea ba sejo se tlase sa carb, empa se kopantsoe le batho ba nang le lefu la liphio);
- Boikoetliso bo phahameng ba 'mele (ho tsamaea, ho matha, boikoetliso ba' mele);
Ho feta moo, lijo le ho ikoetlisa ke tsa bohlokoa haholo ho ntlafatsa boemo ba mokuli. Phekolo ena e thusa ho boloka tsoekere e tloaelehileng ea mali.
Ho bohlokoa ho totobatsa hore lefu la tsoekere le itšetlehileng ka insulin ke lefu le sa phekoleheng, hobane li-b-cell tsa manyeme a senotsoeng ke corticosteroids ha li sa khutlisoa.
Haeba tlhahiso ea "insulin" e sa senyeha ka botlalo 'me lisele tsa tšoelesa li tsoela pele ho hlahisa li-hormone, joale mokuli o etsa tsoekere e sa itšetleheng ka insulin, e lumellanang le lefu la tsoekere la mofuta oa 2.
Bakeng sa kalafo ea eona e hloka:
- Ho tsamaellana le sejo se tlase sa carb;
- Boikoetliso bo tlamehang;
- Ho sebelisa lithethefatsi tse eketsang kutloisiso ea lisele tsa mmele ho insulin: Glucophage, Thiazolidinedione le Siofor;
- Ho loantša boima bo feteletseng (haeba bo teng);
- E lumelletsoe liente tsa insulin ho boloka tšoelesa e amehang.
Ka mofuta ona oa lefu la tsoekere, ts'ebetso ea pancreatic e ka fola ka botlalo, ho bolelang hore lefu la tsoekere le sa itšetleheng ka insulin le ka phekoleha.
Haeba mokuli a fumanoe a e-na le lefu la tsoekere, empa a sa khone ho hana ho nka corticosteroids (mohlala, ka ho fetisoa hoa meno kapa asthma e matla ea bronchial), o fuoa lihormone tsa anabolic ho thusa ho fokotsa matla a lithethefatsi tsa glucocorticoid. Phekolo e joalo e thusa ho boloka bophelo ba mokuli. Lintlha tse mabapi le bothata li videong ena.
