Cyprolet 250 mg ke sethethefatsi se sebetsang sa antibacterial se nang le litla-morao tse fapaneng tsa kalafo. E sebelisoa ho phekola mafu a mangata a tšoaetsanoang. Moriana o ka fuoa bakuli ba nang le ts'oaetso ea mmele e fokotsang.
ATX
Setlhare sena se kenyelelitsoe sehlopheng sa lithibela-mafu tsa "quinolone" molokong oa bobeli. Ho latela sehlopha sa ATX, e na le khoutu ea J01MA02.
Cyprolet 250 mg ke sethethefatsi se sebetsang sa antibacterial.
Lokolla liforomo le sebopeho
Setlhare se rekisoa ka mefuta e latelang ea litekanyetso:
- matlapa a koahetsoeng ka filimi ea 250 kapa 500 mg;
- tharollo bakeng sa tsamaiso ea methapo ea 2 mg / ml;
- ophthalmic e theoha 3 mg / ml.
Cyprolet ka mokhoa oa liente, litlolo, litlolo ha li etsoe.
Matlapa a pota-potile, a biconvex, a na le khetla e tšoeu, e mosehla nakong ea khefu. Ciprofloxacin hydrochloride e ile ea hlahisoa ka har'a motsoako e le ntho e sebetsang. Ho tlatsa ho thusang ho kenyeletsa microcrystalline cellulose, anhydrous colloidal silicon diabetes, starch, croscarmellose sodium, stearate le magnesium hydrosilicate. Motsoako oa enteric o na le talc, polyethylene glycol, hypromellose, dimethicone, polysorbate 80, titanium dioxide (E171), le sorbic acid.
Matlapa a 10 a pakiloe. ka har'a mekotla ea lithutsoana. Lerata le le leng le kentsoe lipakete tsa karete hammoho le litaelo tsa ho li sebelisa.
Mefuta e meng ea lithethefatsi ka tekanyetso ea 250 mg ha e fumanehe.
Ciprofloxacin ke ntho e sebetsang ea Ciprolet 250.
Ketso ea pharmacological
Setlhare se bonts'a thepa ea bactericidal. Ha e le ntho e sebetsang, ciprofloxacin e sebelisoa - anti-wide spectrum fluoroquinolone antibiotic. Ka seleng ea baktheria, e sebetsa e le ntho e thibelang li-enzyme tsa topoisomerase, eo ho buuoang ka eona ka ho theknoloji ea DNA. Ka lebaka la ketso ea eona:
- biosynthesis ea protheine e senyehile;
- Ho pheta-pheta ha DNA ho thibetsoe;
- liphetoho tsa sebopeho sa membrane;
- khetla ea kantle e felisitsoe;
- kholo ea lisele ea emisa;
- ho hlahisa likokoana-hloko ho fetoha;
- likokoana-hloko lia shoa.
Ho jala likokoana-hloko tse sebetsang le tse kenang habonolo li angoa ke moriana. Ho hang ha ho na mefuta e phehellang ka mor'a kalafo, ka hona ho loants'oa lithibela-mafu ho hlahisoa butle butle.
Cyprolet e sebetsa hantle ntoeng khahlanong le li-aerobes tse ngata.
Ciprofloxacin e sebetsa hantle ho loants'eng li-aerobes tse ngata, tse ntle tsa gram, tse seng ntle le gram, intracellular, β-lactamase tse hlahisang likokoana-hloko:
- staphylococci;
- mefuta e meng ea streptococci;
- ntaramane ea mokokotlo;
- Liprotheine
- li-vibrioes;
- legionella;
- Klebsiella;
- Enterobacteria;
- salmonella;
- Escherichia coli;
- lisare;
- cytobacteria;
- brucella;
- Pseudomonas aeruginosa;
- Shigella
- chlamydia.
Motsoako o mongata oa lithibela-mafu o ama anaerobes, o sitoa ho sebetsana le Stenotrophomonas maltophilia, Bacteroides fragilis, Burkholderia cepacia, treponema, myco- le ureaplasma, pneumococcus, bacteroids, pathogens ea pseudomembranous colitis le nocardiosis, haholo methicystic. Ha nako e ntse e tsamaea le ho latela sebaka, maikutlo a likokoana-hloko a ka fetoha.
Ka media ea otitis, ho bontšitsoe Cyprolet 250 mg.
Mofumahali
Ho tsoa ho tšilo ea lijo, moriana o kenngoa ka lihora tse 1-2. Litaba tsa plasma tsa ciprofloxacin ka tekanyo ea 250 mg ke 1,2 μg / ml. Bioavailability e ka ba 75%. Ho ja ho fokotsa sekhahla sa ho kenngoa ka mpeng e nyane, empa ha ho ame matšoao a mang. Ha e sebelisoa kaholimo ho sebopeho sa pono (marotholi), ho kenella ka mokhoa o fokolang maling ho bonoa.
Motsoako oa lithibela-mafu o ajoa hantle 'meleng. E feta sehikeng sa placental, e pepesetsoeng lebeseng la matsoele, e ikemiselitsoe ka har'a mokelikeli oa "cerebrospinal" leha ho se na ts'oaetso ea lehae. Likahare tsa eona linama li na le makhetlo a mangata ho feta likhakanyo tsa plasma. Ka bophahamo bo sebetsang, e kena mats'oafong, mokokotlong oa bronchial, seshe, sebete, bile, musculoskeletal system, mokelikeli o kopaneng, litho tsa genitourinary, tonsils, lits'oants'o.
Metabolism ha e fetele 30%, e tsamaisoang ke sebete. Lihlahisoa tsohle tse bolileng lia sebetsa, empa kenella phallo ea mali maemong a tlase. Ho hloekisa 'mele ho nka lihora tse 6 ho isa ho tse tšeletseng. Metabolites le ciprofloxacin e sa fetoheng e pepesitsoe haholo ka har'a moroto. Palo e nyane e ntšoa ka mantle. Ka litlolo tse amanang le lefu la mokokotlo, nako ea bophelo ke lihora tse 12. Nako ea lilemo ha e ame pharmacokinetics.
Ho thusang
Moemeli oa meriana eo ho buuoang ka eona o sebelisetsoa ho felisa tšoaetso ea baktheria, ho kenyelletsa le e sa boleloang. Matšoao a sebeliso:
- Maloetse a ENT - otitis media, mastoiditis, sinusitis, tonsillitis, pharyngitis, nasopharyngitis, tonsillitis.
- Matsoafo a tsamaiso ea methapo - bronchitis (a hlobaetsang le a sa foleng a sa foleng), leqhetsoana la matšoafo le empyma, pleurisy, pneumonia, ntle le ha a halefisitse Streptococcus pneumoniae.
- Maloetse a amanang le lijo tsa lijo tse amanang le lijo tse amanang le tšilo ea lijo a re ts'oara - Campylobacteriosis, k'holera, salmonellosis, shigellosis, typhoid, enteritis, colitis.
- Tšoaetso ea liphio le ducts ea moroto - cystitis, nephritis, urethral syndrome.
- Tšoaetso ea genital - oophoritis, ho ruruha ha tšoelesa ea senya, endometritis, adnexitis, chancre e bonolo, lesapo la chlamydial, gonorrhea.
- Peritonitis
- Anthrax (tšoaetso ea pulmonary).
- Septicemia.
- Tšenyo ea masapo, manonyeletso a 'ona, letlalo le linama tse sa potang - osteomyelitis, carbuncle, furuncle, phlegmon, abscess, ts'oaetso ea libaka tsa maqeba, ramatiki ea purulent, bursitis.
Ciprolet e ka sebelisoa e le karolo ea kalafo e rarahaneng ea antibacterial. Ka linako tse ling e sebelisetsoa merero ea thibelo - ka ho buoa, bakuli ba nang le neutropenia, bakuli ba noang meriana ea immunosuppressive, ho kenyelletsa le ho thibela nts'etsopele ea anthrax le meningitis.
Cyprolet 250 ha e khethoe nakong ea kemolo.
Contraindication
Lithethefatsi ha li fuoe ho latela:
- mamello ho sebopeho;
- nalane ea allergy ho fluoroquinolones;
- ho hlaseloa ha pseudomembranous colitis;
- boimana
- sefuba.
E tšoaelitsoe bakuli ba ka tlase ho lilemo tse 18. Ts'ebeliso ea moriana o thibelang likokoana-hloko ho bana e lumelletsoe feela ho bana ba nang le mathata a tšoaetsanoang a cystic fibrosis kapa, haeba ho hlokahala, kalafo / prophylaxis ea anthrax ea pulmonary. Mona monyako oa lilemo o theotsoe ho lilemo tse 5.
Ka tlhokomelo
Ho lokela hore ho sebelisoe tlhokomeliso maemong a sa foleng a a amanang le a renal, "myasthenia gravis" e senyehileng, tšenyo ea sebete, ts'oaetso ea mali e kenang bokong, monyetla oa ho ts'oaroa ke sethoathoa, ho lemala ha mafu a kelello le ha o fana ka litlhare ho bakuli ba tsofetseng.
Ciprolet 250 e laetsoe ka hloko bakeng sa tšenyo ea sebete.
U ka nka Ziprolet 250 joang
Sethethefatsi se laetsoe ke ngaka. Matlapa a koahetsoe ka membrane e sirelletsang mucosa ea ka mpeng litlamong tse mpe tsa meriana e thibelang likokoana-hloko, ka hona ha ea lokela ho sithabetsoa kapa ho hlafuna. Moriana oa molomo o tsamaea le mokelikeli o mongata. Cyprolet ha e lumellane le lihlahisoa tsa lebese. Ho ja lijo ho thibela ho kenngoa ha motsoako o sebetsang. Tabeng ena, matlapa a khothalletsoa hore a noe ka mpeng e se nang letho kapa lihora tse peli kamora ho fela ha lijo.
Litekanyetso li beoa ke ngaka, li ela hloko mefuta e mengata e fapaneng. Nako e khothalletsoang pakeng tsa tekanyetso ke lihora tse 12. Ka ho kheloha ho matla mosebetsing oa liphio, tekanyetso e tlase e behiloe, khafetsa ea ho amoheloa e fokotsoa ho 1 nako ka letsatsi. Ka linako tse ling tsela ea kalafo ho bakuli ba baholo e qala ka ho kenyelletsa infusion ea ciprofloxacin.
Ebe mokuli o lokela ho nka moriana o thibelang likokoana-hloko ka molomo.
Mokelikeli oa infusion o lumellana le tharollo:
- sodium chloride 0,9%;
- dextrose 5% le 10%;
- fructose 10%;
- Ringer's.
Matlapa a 250 mg a ka sebelisoa ho phekola bana ho tloha ho lilemo tse 5 ho loantša Pseudomonas aeruginosa le Bacillus anthracis (tlasa taolo e thata ea bongaka).
Cyprolet 250 e ka nkuoa boteng ba lefu la tsoekere.
Tsela ea kalafo e ka fapana. Hangata ke matsatsi a 5-7, empa ka linako tse ling ho nka libeke kapa likhoeli tse 'maloa ho felisa tšoaetso. Likokoana-hloko tse ling li na le tšekamelo e tlase ea ts'ebetso ea moriana, ka hona, ho fanoa ka litlhare tse eketsehileng tsa lithibela-mafu, ka mohlala, ka tšoaetso ea lefua la lefutso la lefutso - beta-lactams.
Na hoa khoneha ho nka moriana oa lefu la tsoekere?
Lithethefatsi tse ho buuoang ka tsona li ka nooa boteng ba lefu la tsoekere. Le ha ho le joalo, re lokela ho hopola hore e ka baka tsoelo-pele ea hypo- kapa hyperglycemia.
Ho laoloa tsoekere ea mali hoa hlokahala.
Litlamorao
Moriana o ka baka karabelo e mpe litsing tse fapaneng. Li hlaha khafetsa, litlamorao tse mpe li etsahala khafetsa.
Phekolo ea ka mpeng
Takatso ea lijo e theohileng kapa ho se be teng ha eona, lets'ollo, ho nyekeloa le pelo le ho hlatsa, bohloko ba ka mpeng, ho senyeha hoa mala, ts'ebetso e eketsehileng ea li-enzyme tsa sebete, hepatitis, jaundice ka lebaka la cholestasis, hepatonecrosis.
Ho nyekeloa ke pelo le ho hlatsa hangata ke litla-morao tsa Ciprolet 250.
Hematopoietic litho tsa ka hare
Khatello ea moko oa masapo, phetoho ea sebopeho sa mali ho fihlela pancytopenia.
Tsamaiso ea methapo e bohareng
Vertigo, migraine, ho felloa ke matla, khatello ea maikutlo, ho tšoenyeha, ho tšoha haholo, ho ferekana ha maikutlo a psychomotor, pono, ho hloka boroko, ho lora bosiu, ho tepella maikutlo, ho felloa ke matla ha maikutlo, ho ferekana, ho thothomela, bohloko mesifa le manonyeletso.
Ho tsoa ts'ebetsong ea moroto
Motsoako o fokotsehile, ho hlahella ha litšila tse nang le mali le likristale tsa letsoai ho lona, le tšenyo e bakang liphio.
Ho tsoa ho tsamaiso ea methapo ea pelo
Ho sutumetsa ha mali hloohong, ho utloa mocheso, ho ferekana ha morethetho oa pelo, ho fokotseha ha khatello ea mali, tachycardia ea nakoana, ho lelefatsa nako ea QT ho ECG, litekanyetso tse phahameng tsa bilirubin, urea le tsoekere ea mali.
Nakong ea kalafo le Ciprolet 250, ho nwa joala ho kontšoa.
Allergie
Ho hlohlona, ho ruruha, ho ruruha, ho ruruha, feberu, ho boloka secretion, Stevens-Johnson syndrome, bronchospasm, anaphylactoid reaction.
Litaelo tse khethehileng
Kamora ho felisa matšoao a lefu lena, matlapa a lokela ho nooa matsatsi a mang a 2-3.
Ka lebaka la ho nka meriana, pseudomembranous colitis e ka hlaha, e hloka kalafo e potlakileng. Lets'ollo le amanang le lithibela-mafu ha le khone ho felisoa ka khatello ea mokokotlo.
Haeba matšoao a senya ts'ebetsong ea hepatobiliary (bohloko ba ka mpeng, jaundice, moroto o lefifi, ho hlohlona) o lokela ho emisa ho nka Ciprolet mme o batle thuso ea bongaka.
Ho na le kotsi ea tendinopathy, ho phatloha ha tendon ho ka etsahala. Ho ka hlaha tumela-khoela.
Ka tloaelo ea ho tsitsipana, lefu la sethoathoa, tšenyo ea boko, ho lemala ha methapo ea mokokotlo, ho lemala ka lehata le ka mor'a ho otloa, setlhare sa antibacterial se sebelisoa ka hloko.
E lumelletse ho khethoa ha Cyprolet 250 ho tloha ho lilemo tse 5.
Tekanyo ea joala
Nakong ea kalafo, ho noa joala ho hanyetsoa.
Tšusumetso ho bokhoni ba taolo ea methapo
Lintho tse ka 'nang tsa hlaha ho tsoa ho tsamaiso ea methapo e bohareng, ho kenyelletsa ho tsekela, ho akheha, pono e habeli, ho hokahana ka tsela e fapaneng. Ha matšoao a joalo a hlaha, ho sebetsa ka mekhoa e rarahaneng hoa thibeloa.
Sebelisa nakong ea bokhachane le pelehi
Tšireletseho ea ciprofloxacin bakeng sa lesea le sa tsoa emoloa e-so ka e thehoa, ka hona, sethaleng sa moimana, basali ha ba fuoe meriana. Haeba ho hlokahala ho nka motsoako oa motsoako ke mme ea anyesang nakong ea kalafo, ngoana o lokela ho fetisetsoa phepong ea maiketsetso.
Ho khethoa bana ba bana ba 250
Karolo e sebetsang ea lithethefatsi e ka qala nts'etsopele ea arthropathy, ka hona, ho fihlela a le lilemo li 18, ho fihlela ho thehoa likarolo tsa mokokotlo oa mokokotlo, ho sa rateheng haholo ho sebelisa lithibela-mafu. E ka laeloa ho bakuli ho tloha lilemong tse 5 ho hatella ts'ebetso ea Pseudomonas aeruginosa ho cystic fibrosis le joalo ka moemeli oa kalafo le prophylactic bakeng sa anthrax (ts'oaetso ea pulmonary).
Analog ea Cyprolet 250 ke Citral.
Bongata
Ha u nka tekanyetso e phahameng, matšoao a itseng ha a hlahe. Matšoao a chefo, hlooho ea hlooho, makhopho, hematuria a bonoa, ho lahleheloa ke kelello ho ka etsahala. Kamora ho hlaseloa ke mpa, ho phekoloa ka matšoao. U sebelisa dialysis, ho ke ke ha khoneha ho tlosa ho feta 10% ea ciprofloxacin.
Ho sebelisana le lithethefatsi tse ling
Motsoako oa koprofloxacin le tizanidine ha o amohelehe. Sena se ka lebisa ho fokotseha ho matla ha khatello, ho tsekela le ho akheha. Kameho ea lithethefatsi e ka matlafatsoa ke Vancomycin, Clindamycin, Tetracycline, Metronidazole, penicillin le aminoglycoside lithibela-mafu, Zinnat le li-cephalosporins tse ling. Boteng ba hae, ho tsepamisa mohopolo oa plasma ea anticoagulants, xanthines, hypoglycemic le lithibela-mafu tse seng khahlanong le ho ruruha (ntle le Aspirin) li eketseha.
Ho amoheloa ha ciprofloxacin ho tsoa mokokotlong oa mokokotlo ho kenngoa ts'ebeliso ea meriana e nang le aluminium, zinki, tšepe kapa ion ea magnesium, 'me tlhahiso ea eona e liehisoa ke tsamaiso ea Probenecid. Tšebeliso e tšoanang ea lithethefatsi tse amanang le Cyclosporine e ka baka keketseho ea mahlaseli a plasma a creatinine.
Cyprolet 250 ke lengolo la ngaka.
Li-analog tsa Tsiprolet 250
Lithethefatsi tse tšoanang le ena:
- Ciprofloxacin;
- Tsiprova;
- Arflox;
- Athenoxime;
- Cypropane;
- Citral
- Medociprine, jj.
Lipehelo tsa khefu ea khemisi
Motsoako oa lithibela-mafu ha o reretsoe ho rekisoa mahala.
A na nka reka ntle le lengolo la ngaka?
Moriana ke ngaka.
Theko
Litsenyehelo tsa matlapa a ho kopantseng ha enteric li tsoa li-ruble tse 56. bakeng sa li-pcs tse 10.
Maemo a polokelo ea Tsiprolet 250
Mocheso oa polokelo - ho fihlela ho + 25 ° С. Qoba mongobo o phahameng le khanya ea letsatsi ka kotloloho.
Letsatsi la ho felloa ke nako
Setlhare se ka sebelisoa nakong ea lilemo tse 3 ho tloha ka letsatsi la tlhahiso. Meriana e felileng e tlameha ho lahloa.
Tlhahlobo ea Tsiprolet 250
Moemeli oa pharmacological tlas'a tlhokomelo e fumana litlhahlobo tse ntle haholo. Likarabo tse mpe li amahanngoa le ho se sebetse hantle ha pathogen kapa mamello e mpe maemong a le mong.
Lingaka
Zinovieva T. A., otolaryngologist, Saratov
Sesebelisoa se matla sa lithibela-mafu, ke se sebelisa hangata tloaelong ea ka.
Tishchenko K.F., ngaka e akaretsang, Moscow
Sesebelisoa se hantle sa antibacterial se nang le mofuta o bonolo oa litekanyetso. Ke khothaletsa ho e nka ka li-probiotic ho boloka microflora ea mala.
Bakuli
Anna, ea lilemo li 24, Rostov
Ke nkile lipilisi tsa cystitis. Ke ile ka ikutloa ke imoloha kapele. Ha ke a hlokomela litla-morao.
Tatyana, ea lilemo li 56, Irkutsk
Sesebelisoa se theko e tlaase le se sebetsang. Ke e noetse ka sefuba se matla, ebe ke furunculosis. E mamelloa hantle, ho fapana le lithibela-mafu tse ling, 'me ha e baketsele.
