Bakeng sa kalafo ea mafu a ea gastrointestinal pampitsana le mathata a metabolic nka metabolic mahlahana. Setlhare se seng se sebetsang ke thioctic (alpha lipoic) acid.
Lebitso la Machaba le sa Tšoanelehang
Thioctic asiti.
Bakeng sa kalafo ea mafu a gastrointestinal pampitsana le mathata a metabolic, ho nkoa thioctic acid.
ATX
A16AX01
Sebopeho
Ho hlophisoa ha letlapa le le leng ho kenyelletsa 300 mg le 600 mg ea thioctic acid (karolo e sebetsang). Motsoako oa filimi oa letlapa o na le lintho tse kang: hypromellose, titanium oxide, silicon oxide, dibutylsebacate, talc. Sesebelisoa se kenngoa ka mekotleng ea karete.
Ketso ea pharmacological
Moriana o na le litlamorao ho 'mele joalo ka:
- antioxidant;
- hypocholesterolemic;
- lipid-lowing;
- hepatoprotective;
- phetisetso.
Matlapa a Thioctic acid ke antioxidant ea emong. Ka mofuta oa ts'ebetso ea biochemical, lithethefatsi li haufi le livithamini tsa B. Moriana o thusa ho ntlafatsa trophism ea li-neurons, o fokotsa bongata ba mali maling, o eketsa seleng ea glycogen ka har'a sebete, hape o fokotsa ho hanyetsa insulin.
Moriana o kentse letsoho taolong ea metabolism.
Mori o nka karolo taolong ea metabolism (lipid le carbohydrate), e ntlafatsa metabolism ea cholesterol, e ntlafatsa ts'ebetso ea sebete. Alfa-lipoic acid e boetse e kenella ho metabolism ea mitochondrial kahare ho sele.
Mofumahali
Kamora ho tsamaisoa ka molomo, sethethefatsi se kenngoa ka potlako ho tsoa mokokotlong oa mpa. C max e fihlelleha kamora 0.5 -1 h. Bioavailability ke 30-60% ka lebaka la kemiso ea lintho tsa tlhaho. E kopantsoe le ho kopanngoa 'meleng,' me e buelloa ke liphio ka 80-90% ka sebopeho sa metabolites.
Matlapa a thioctic acid ke afe?
Setlhare sena se ka sebelisoa ho phekola li-pathologies tse latelang:
- hepatitis e sa foleng;
- ho hloleha ha sebete ho matla;
- cirrhosis ea sebete;
- lino tse tahang;
- coronary atherosclerosis;
- mofuta o sa foleng oa cholecystopancreatitis;
- jaundice e nang le vaerase ea hepatitis;
- joala le lefu la tsoekere la polyneuropathy;
- dyslipidemia;
- pancreatitis e sa foleng e hlahisoang ke bokhoba ba tahi;
- chefo ka lipilisi tsa ho robala, carbon tetrachloride, tšepe tse boima kapa khabone;
- lefu la sebete la mafura;
- phallo ea mali e tlase ea mali;
- tšoaetso ea likokonyana;
- botenya.
Contraindication
Se ke oa sebelisa meriana:
- nakong ea ho anyesa;
- boteng ba mamello ea motho ka mong ho likarolo tsa moriana;
- basali baimana;
- bana ba ka tlase ho lilemo tse 6.
Mokhoa oa ho nka matlapa a thioctic acid
Haeba u batla ho theola boima ba 'mele, ho hlokahala hore u noe 50 mg ea moriana pele ho lijo tsa hoseng kapa ka mor'a tsona.
Boteng ba mafu a sebete le botaoa, ba nooa ka molomo makhetlo a 50 mg makhetlo a 3-4 ka letsatsi (batho ba baholo). Bana ba lilemo li 6 - 12-24 mg makhetlo a mararo ka letsatsi. Lipilisi li nooa metsotso e 30 pele ho lijo. Tsela ea kalafo e nka matsatsi a 20 ho isa ho a 30.
Ka ho haha 'mele
Baatlelete ba baholo ba hloka ho noa makhetlo a 50 mg makhetlo a 3-4 ka letsatsi ka mor'a lijo. Ka ho ikoetlisa haholo 'meleng, litekanyetso tsa letsatsi le letsatsi li eketseha ho fihlela 300-600 mg.
Baatlelete ba baholo ba hloka ho noa moriana ona ka makhetlo a 50 mg makhetlo a 3-4 ka letsatsi ka mor'a lijo.
Khafetsa ho haha 'mele, matlapa ana a kopantsoe le Levocarnitine le li-complexes tsa vithamine, kaha li thusa ho lokolla mafura liseleng, ho susumetsa tšebeliso ea matla.
Le lefu la tsoekere
Batho ba nang le lefu la tsoekere ba lokela ho nka karolo ea 600 mg ea moriana hang ka letsatsi, ba noe pompo ka metsi a hloekileng. Phekolo e qala feela kamora 'libeke tse 2-4 tsa ho tsamaisoa ha moriana ka meriana. Nako e fokolang ea ho phekoloa ka matlapa ke matsatsi a 90.
Litla-morao tsa matlapa a thioctic acid
Khahlano le semelo sa ho sebelisa lithethefatsi, ho ka hlaha tse latelang:
- ho nyekeloa
- ho hlatsa
- pelo e bohloko;
- ho thothomela ha anaphylactic;
- urticaria;
- hypoglycemia (metabolism ea glucose e senyehileng);
- khatello e eketsehileng ea intracranial;
- diplopia (ho pheta-pheta ha lintho tse bonahalang);
- hemorrhages e kenang letlalong le li-membrane tsa mucous;
- tloaelo ea ho tsoa mali ka lebaka la ts'ebetso ea mokopu o senyehileng.
Litaelo tse khethehileng
Ha u sebelisa litafole ho bakuli ba nang le lefu la tsoekere, ho hlokahala hore o laole tsoekere ea mali hangata. Haeba ho hlokahala, fokotsa litekanyetso tsa lithethefatsi tsa antidiabetes.
Mosebetsi ho bana
Moriana ona ha o fuoe bacha ba ka tlase ho lilemo tse 18 kalafo ea lefu la tsoekere le joala la joala.
Sebelisa nakong ea bokhachane le pelehi
Ha ho khothalletsoe ho sebelisa lithethefatsi nakong ea ho emara le ho lactation.
Tekanyo ea joala
Setlhare se ke ke sa kopantsoe le tšebeliso ea lino tse tahang, hobane li fokolisa phello ea thioctic acid.
Tšusumetso ho bokhoni ba taolo ea methapo
Moriana ha o ame bokhoni ba taolo ea methapo.
Bongata
Haeba litekanyetso tsa lithethefatsi tse lumelloang li feta, ho ka etsahala:
- lets'ollo
- ho nyekeloa
- bohloko ba epigastric;
- ho hema ka thata
- lekhopho la letlalo;
- migraine
- pelo lippitations.
Ho sebelisana le lithethefatsi tse ling
Moriana ka mokhoa oa litafole o ntlafatsa phello ea kalafo ea lithethefatsi tsa hypoglycemic ea molomo le insulin.
Moriana o ka ntlafatsa phello ea li-glucocorticosteroids le ho thibela tšebetso ea cosplatin.
Matlapa ana ha a khothalletsoe ho kopanngoa le meriana e nang le li-ion tsa tšepe.
Li-analog
Lethathamo la analogues:
- Alpha lipoic acid (phofo);
- Tiolepta;
- Thiogamma;
- Thioctacid;
- Espa-Lipon (tharollo ea ente).
Lipehelo tsa khefu ea khemisi
Matsatsi a phomolo a ho fuoa lengolo.
A na nka reka ntle le lengolo la ngaka?
Che.
Theko
Litsenyehelo tsa pakete e le 'ngoe ea meriana (matlapa a 50) ke li-ruble tse 60.
Maemo a polokelo ea moriana
Ho hlokahala ho boloka lithethefatsi ka mocheso oa + 15 ... + 25 ° C mochesong o omileng, o lefifi ebile o sa fihlelehe ho bana.
Ho hlokahala ho boloka lithethefatsi ka mocheso oa + 15 ... + 25 ° C mochesong o omileng, o lefifi ebile o sa fihlelehe ho bana.
Letsatsi la ho felloa ke nako
Likhoeli tse 36 ho tloha ka letsatsi la tlhahiso, tse bontšitsoeng lebokoseng la karete.
Moqapi
OJSC "Marbiopharm", Russia.
Litlhahlobo
Lingaka
Petr Sergeevich, ea lilemo li 50, setsebi sa phepo e nepahetseng, Volgograd
Thioctic acid e potlakisa phetoho ea lik'habohaedreite tse sa hlokahaleng hore e be matla. Ka lebaka la sena, li-depositi tsa mafura li qala ho fokotseha, 'me takatso ea lijo ea fokotseha. Bakeng sa batho ba batenya haholo, ke khothaletsa ho sebelisa meriana ena hammoho le phepo e nepahetseng le boikoetliso ba 'mele.
Maria Stepanovna, ea lilemo li 54, setsebi sa mafu a kelello, Yalta
Matlapa ana ke sesebelisoa se sebetsang kalafo ea mafu a mangata. Ketso ea sethethefatsi e etselitsoe ho laola metabolism ea carbohydrate le lipid, ho etsa hore maemo a cholesterol a fokotsehe, hammoho le ho ntlafatsa ts'ebetso ea sebete le ho loants'a tahi ea methapo e mengata. Setlhare se mamelletsoe hantle, maemong a sa tloaelehang, ho na le litletlebo tsa hlooho le mokhathala.
Ekaterina Viktorovna, ea lilemo li 36, setsebi sa endocrinologist, Saratov
Ke fana ka moriana ona ho bakuli ba nang le lefu la tsoekere la polyneuropathy. Ka nako e ts'oanang, ke hlahloba boemo ba tsoekere maling maling haholo-holo qalong ea kalafo. Thioctic acid e bonts'a katleho e phahameng ho kalafo ea lefu lena.
Bakuli
Victor, ea lilemo li 45, Tufall
Ke nwa lipilisi tsena joalo ka ha ke laetsoe ke ngaka ho theola cholesterol ea mali. Setlhare ha se tlose li-acid tse kotsi tse tsoang 'meleng feela, empa se ama le' mele oohle. Kamora 'nete ea maemo, boemo bo ile ba ntlafala. Kamora matsatsi a 14 a ho nka lipilisi tsena, boemo ba cholesterol bo ile ba fokotseha.
Grigory, ea lilemo li 42, Novorossiysk
O ile a sebelisa kalafo ena ka khothaletso ea ngaka ea hore a fetole tsoekere e maling. Ho latela lipontšo tsa laboratori - ntho e tloaelehileng, sethethefatsi se khahloa ke ts'ebetso. Hona joale ke nooa lipilisi tsena hang ka selemo molemong oa thibelo.
