Oktolipen ke meriana ea meloko ea ho qetela ka mokhoa oa tharollo ea infusion. Oktolipen ea mofuta oa 2 lefu la tsoekere e sebelisoa ho laola metabolism ea carbohydrate le lipid, ho fokotsa tsoekere ea mali le ho lahleheloa ke liponto tse eketsehileng.
Moriana o boetse o sebelisoa haholo bakeng sa mefuta e meng ea lefu la tsoekere e le karolo ea kalafo e rarahaneng. Oktolipen e na le litlhahlobo tse ntle haholo tse tsoang ho batho ba nang le lefu la tsoekere.
Oktolipen e fumaneha hape ka sebopeho sa capsule le tafole.
Oktolipen
Oktolipen ke antioxidant ea endo native e tlamang li-radicals tsa mahala. Ts'ebetso ena e etsahala nakong ea oxidative decarboxylation ea alpha-keto acid.
Ha e le coenzyme, sethethefatsi se kenella ho decarboxylation ea pyruvic acid le alpha-keto acid. E na le matla a ho theola tsoekere ea mali, hammoho le ho eketsa glycogen sebete le ho hlola insulin ho hanyetsa. Kahoo, e ka sebelisoa bakeng sa lefu la tsoekere la mofuta oa 2.
Thioctic acid e haufi le livithamini tsa B. Ntho ena e na le litlamorao tse latelang:
· E nka karolo taolong ea metabolism ea lipid le carbohydrate,
· E ntlafatsa metabolism ea cholesterol,
· E thusa sebete.
Setlhare se na le:
1. Hypocholesterolemic,
2. hepatoprotective,
3. lipid-theoha,
4. phello ea hypoglycemic.
Ka thuso ea sesebelisoa trophism ea li-neurons e ntlafalitsoe, hammoho le kholiseho ea axonal le ho teba ha joala le tahi ea polyneuropathy e fokotsehile.
Lithethefatsi Okolipen le laetsoe feela ke ngaka e eang ka bonngoe. Ho thibetsoe ho etsa kalafo ka kalafo ena.
Octolipene ka ampoules ke sesebelisoa se kopanetsoeng se hlokahalang ho theha tharollo ea methapo. Mokelikeli o pepesitsoe, o putsoa ka botala le o mosehla.
Ho 1 millilita ea lithethefatsi ke thioctic kapa lipic acid e 30 mg. Ampoule e le 'ngoe e na le makholo a mararo a metsoako ea ntho ena.
Likarolo tse thusang ke:
- disodium edetate,
- ethylenediamine
- metsi a qhibilihileng.
Setlhare sena se fumaneha ka li-ampoules tsa khalase tse lefifi ka bongata ba limililitara tse 10. Sephutheloana ke pakete ea karete, ka pakete e le 'ngoe - 5 ampoules.
Setlhare sena se boetse se rekisoa ho li-capsules tsa Octolipen 300 le matlapa a Okolipen 600.
Litaelo tsa ho sebelisoa Oktolipen
Ho lokisa tharollo ea infusion, ho hlokahala hore u hlapolle li-ampoule tse 1 kapa tse 2 ho 50-250 di ml tsa 0,9% sodium chloride. Tharollo e fanoa ke lerotholi, ka methapo. E sebelisoa hang ka letsatsi bakeng sa 300-600 mg bakeng sa libeke tsa 2-4. E latelang, o hloka ho fetohela kalafo ea molomo.
Sesebelisoa se na le photosensitivity, ho bolelang hore li-ampoules li tlameha ho tlosoa hang-hang pele li sebelisoa.
Ho molemo ho sireletsa sejana ka tharollo ho tloha leseli nakong ea infusion, ka mohlala, u sebelisa mekotla ea foil kapa e sireletsang bobebe. Tharollo e entsoeng e bolokiloe sebakeng se lefifi mme e sebelisoa lihora tse tšeletseng kamora ho itokisa.
Haeba ngaka e laetse tsela ea kalafo le Oktolipen, ho bohlokoa ho nahana ka lintlha tse latelang:
- lipoic acid e ka hloka liphetoho litekanyetso tsa lithethefatsi tse ling le lihlahisoa tsa lijo,
- haeba moriana o kenyelelitsoe ho thibelo e felletseng le kalafo ea lefu la tsoekere, ho bohlokoa ho lekola palo ea tsoekere maling e sebelisa glucometer, ho etsa liphetoho ka tekanyo ea li-hypoglycemic agents.
- Sesebelisoa se sebetsang sa lithethefatsi se ts'oana le ts'ebetso ho livithamini tsa B, empa ha se tlatsetso ea vithamine. Ho sebelisa sehlahisoa ntle le ho buisana le ngaka ho ka mpefatsa mathata a bophelo bo botle.
Ketso ea pharmacological
Lipoic acid e thehoa kahare ho mmele nakong ea lits'oaetso tsa oxidative tsa acid ea keto. Matla a eona a ho felisa karabelo ea metabolic ea metabolism ho insulin e netefalitsoe. Lipoic acid e ama sebete ka ho toba, e leng bohlokoa ho lefu la tsoekere la mofuta oa 2.
Hona joale moriana o sebelisoa khafetsa botoneng haeba ho na le tlhahlobo ea lefu la tsoekere la mofuta oa 2 kapa ntle le tlhahlobo e joalo.
Lipoic acid e ama hantle litokelo tsa polokelo ea mafura a 'mele. Tlas'a tšusumetso ea asiti ena, libaka tsa polokelo ea mafura lia senyeha ebe ho lokolloa matla a mangata. Bakeng sa ho fokotsa boima ba 'mele, ho bohlokoa hape ho eketsa ts'ebetso ea' mele le ho latela lijo tsa kalafo.
Lipoic acid e nka lik'habohaedreite, empa li li fetisetsa eseng li-adipose tiske, empa ho li isa mesifa ea mesifa, moo li sebelisoang kapa li sebelisetsoang mosebetsi oa mesifa. Ka hona, moriana o sebelisoa ho fokotsa boima ba 'mele feela hammoho le lijo le lipapali.
Liphuputso tse ngata li bontša hore thioctic acid ha e na phello e tobileng ea anabolic.
Oktolipen e fokotsa ka nepo palo ea acid e lactic liseleng tsa mesifa e thehang nakong ea boikoetliso. Motho o fumana monyetla oa ho mamella khatello ea maikutlo le nako e telele, e amang hantle boiketlo ba motho le ponahalo ea hae.
Lipoic acid e eketsa tsoekere ea tsoekere ka lisele tsa mesifa. Kahoo, le thupelo e nyane e tla etsa hore ho be le boemo bo tšoanang ka mor'a ho noa tee. Re lokela ho hopola hore ha o ikoetlisa, metabolism e ka seleng e eketseha ka potlako, 'me palo e kholo ea li-radicals tsa mahala li hlaha, tse sa nke lehlakore habonolo ke lipoic acid.
Contraindication le lipontšo
Oktolipen e laeloa batho ba nang le polyneuropathy e thehiloeng ea lefu la tsoekere le joala.
E boetse e bontšoa bakeng sa cirrhosis le neuralgia, tahi e nang le letsoai la tšepe e boima. Batho ba nang le maikutlo a phahameng ba lokela ho nka lithethefatsi ka hloko.
Ha o sebelisa meriana ena, ho ka ba le litlamorao tse latelang:
- ho opeloa ke pelo, ho nyekeloa ke pelo, ho hlatsa,
- ho hlaha hoa karohano e bakoang ke lintho tsohle,
- hypoglycemia
Matšoao a bosholu ba maikutlo ke:
- ho hlatsa
- ho nyekeloa
- hlooho e bohloko.
Haeba ha u nka thioctic acid ka bongata ba 10 ho isa ho 40 g, lipilisi tse fetang tse leshome tsa 600 mg, kapa ka lethal dose ea tse fetang 50 mg ka kilogram ea boima ba 'mele ho bana, ponahalo ea:
- ho ferekana kelellong kapa ho ferekana ha kelello,
- ho ts'oaroa ka kakaretso
- Liphapang tse tebileng tsa tekano ea acid-msingi le lactic acidosis,
- hypoglycemia (ho fihlela sebopeho sa komisi),
- skeletal skeletal misuli,
- hemolysis
- DIC syndrome
- masapo a mokokotlo
- ho hloleha hoa litho tse ngata.
Haeba e 'ngoe ea lithethefatsi e sebelisoa' me ho hlaha lithethefatsi tse ngata, ho pepesetsoa sepetlele hanghang le ts'ebeliso ea mehato e thehiloeng ho melaoana e akaretsang haeba chefo ea kotsi e ka ba teng. O ka:
- ho hlatsa
- hlatsoa mpa
- nka mashala a sebetsang.
Phekolo ea ho ts'oaroa ka kakaretso, lactic acidosis le litlamorao tse ling tse sokelang bophelo li lokela ho etsoa ho latela melao ea tlhokomelo e matla mme e be sesupo. Ha e na ho tlisa sephetho:
- hemoperfusion,
- hemodialysis
- Mekhoa ea ho filtara ha thioctic acid e hlohlolisoa.
Ho sebelisana le lithethefatsi
Phello ea hypoglycemic ea lithethefatsi e eketseha haeba e nkuoa ka insulin le matlapa a nang le phello e tšoanang. Sena se ka lebisa ho theoha ha tsoekere e maling haholo.
Haeba tšebeliso e kopaneng ea hlokahala, joale hangata e tsamaisana le ho lekola khafetsa tekanyo ea tsoekere e maling. Ha ho kheloha litsela tse sa amoheleheng, litekanyetso tsa insulin kapa li-agents tse ling tsa hypoglycemic li lokela ho fetoloa ka potlako.
Ethanol le metabolites li eketsa monyetla oa litla-morao. Oktolipen ha e lumellane le tharollo ea dextrose le Ringer, hammoho le likhakanyo le tharollo tse arabelang ka ho se lumellane le lihlopha tsa SH le ethanol.
Hape o lokela ho boloka phomolo ea metsotso e 30 pakeng tsa ho ja Okolipen le ho nka lihlahisoa tsa lebese. Ntle le moo, khefu e joalo e sebetsa le ho lithethefatsi tse nang le:
- tšepe
- calcium
Ho boetse ho hlokahala tlhokomeliso ho kopanya Oktolipen le lithethefatsi tse thehiloeng ho magnesium tsa lefu la tsoekere.
Tabeng ena, ho molemo ho sebelisa Oktolipen hoseng, le litokisetso ka magnesium, tšepe le calcium ka shoalane.
Ntle le moo, moriana o joalo o fokotsa botebo ba ketso ea cisplatin, haeba mekhoa e sebelisoa ka nako e le ngoe.
Litšenyehelo le li-analogues
Theko ea lithethefatsi Okolipen ha e holimo haholo. Likarete tse nang le 300 mg ea ntho ea mantlha li tla bitsa li-ruble tse 310.
Matlapa a Octolipen 600 mg a tla bitsa li-ruble tse 640. Ka litlama tsa meriana, u ka fumana alpha lipoic acid ka boeona. E theko e nyane - ke li-ruble tse 80 feela. Theko ea Tiolept e batla e le li-ruble tse 600, Tiogamm e bitsa li-ruble tse 200, Espa-lipon - li-ruble tse ka bang 800.
Mokhoa ha o fapana ka ho sebetsa mme o ka nkeloa sebaka ke o mong:
- Tiolepta
- Berlition,
- Lipothioxone;
- Alpha lipoic acid,
- Tiogamma
- Thioctacid
- Lipamide
- Neuro lipone
- Espa lipon
- Thiolipone.
E atileng ka ho fetisisa, joale ke sethethefatsi Neyrolipon, ke mokhoa o motle bakeng sa Oktolipen.
Thioctacid
Thioctic acid e teng ka tharollo ea Thioctacid, 'me thioctate trometamol e sebelisoa phetolelong ea matlapa.
Thioctacid ke lithethefatsi tsa metabolic tse thusang ho fokotsa lipontšo tsa lefu la tsoekere le joala le noopropathy.
Sesebelisoa se na le:
- antioxidant
- hypoglycemic,
- hepatoprotective effect.
Thioctacid fetisa ts'ebetso ea metabolic 'meleng, e leng bohlokoa ho lefu la tsoekere la mofuta oa 2.
Ho na le mefuta ea litekanyetso:
- lipilisi
- tharollo ea entetso.
Karolo e ka sehloohong ea moriana ke antioxidant ea mehleng. Ho ba teng ha ntho ea 'mele ho fana ka:
- Ho tlosa tsoekere,
- humanization of trophic neurons,
- tšireletso ea selekaneng le chefo,
- ponahatso e fokotsang ea lefu lena.
Antioxidant ena hangata e le 'meleng ka tekanyo e nepahetseng,' me e ts'ehetsa tšebetso ea eona e tloaelehileng.
Ntho e sebetsang e fumanehang ka har'a moriana oa Thioctacid e kenella ka potlako le ka botlalo, 'me e batla e tsoa' meleng ho isa halofo ea hora. Empa ts'ebeliso ea lithethefatsi ka lijo e ama ho amoha ntho ea mantlha. Bioavailability ke 20%.
Ha e le hantle, metabolism e phethoa ka oxidation le conjugation. Ho tlosoa ha bongata ba lithethefatsi ho etsoa ke liphio. Thioctacid hangata e fuoa li-neuropathies tsa lefu la tsoekere.
Setlhare se joalo se boetse se laetsoe li-pathologies tsa sebete. Mohlala, pheko e fanoe ho tsoa ho:
- cirrhosis
- hepatitis e sa foleng
- mafura a senyehileng,
- fibrosis.
Thioctacid e etsa hore ho khonehe ho tlosa phello e chefo e fetohang tšepe.
Theko ea lithethefatsi ka mokhoa oa li-ampoules ke li-ruble tse 1,500, matlapa a theko e phahameng ho tloha ho li-ruble tse 1,700 ho isa ho tse 3 200.
Fumana qeto ea hore na ho molemo ke eng: Thioctacid kapa Oktolipen, ngaka e eang teng e tla thusa. Melemo ea lipoic acid bakeng sa lefu la tsoekere e tla akaretsoa ka video sehloohong sena.
