Formetin ke lithethefatsi tse sebetsang tsa metformin hydrochloride. Tekanyetso: 0.5 g; 0.85 g kapa 1 g. Analogs: Gliformin, Metadiene, Nova Met, NovoFormin, Siofor, Sofamet.
Lintho tse thusang: croscarmellose sodium; seaplane e boima ba molek'hule e phahameng (polyvinylpyrrolidone), magnesium stearate bakeng sa indasteri ea meriana.
Sebopeho sa ho lokolloa: matlapa a tšoeu a potileng-cylindrical a masoeu a nang le facet le kotsi (litekanyetso tsa 0.5 g) le matlapa a tšoeu a oval biconvex a nang le kotsi ka lehlakoreng le le leng (litekanyetso tsa 0,85 g le 1,0 g).
Matšoao a pharmacological
Formethine e fokotsa ho monya ha tsoekere e ka mpeng, e thibela tšebetso ea gluconeogenesis bokong, e ntlafatsa tlhahiso ea glucose, e eketsa kutloisiso ea lisele tsa mmele ho litokisetso tsa insulin.
Maemong ana, formethine:
- Ha e ame tlhahiso ea insulin ke lisele tsa beta tse fumanehang manyeme.
- Ha e tsose nts'etsopele ea boemo ba hypoglycemic.
- Fokotsa palo ea lipoprotein tse fokolang haholo le triglycerides maling.
- E fokotsa boima ba 'mele, e tiisa boima ba' mele ka mokhoa o tloaelehileng.
- E na le phello ea fibrinolytic ka lebaka la khatello ea activator ea tisy ea plasminogen.
Formaline, kamora ho tsamaisoa ka molomo, e kenella butle butle ho tsoa pampiring ea mala. Palo ea lintho tse fumanehang ka mor'a ho sebelisa tekanyetso e tloaelehileng e ka ba 60%.
Khokahano ea tlhapi ea moriana maling e hlaha lihora tse 2,5 kamora ts'ebeliso ea kahare.
Formethine e batla e sa kopanye le liprotheine tsa plasma; e bokellana sebeteng, liphio, mesifa, litšoelesa tse thellang; e pepesitsoeng ke liphio ka mokhoa o sa reroang. Bophelo ba ntho e halofo ke lihora tse 1.5 - 4.5.
Ela hloko! Haeba mokuli a fokolisitse tšebetso ea renal, ho bokelloa hoa moriana 'meleng hoa khoneha.
Matšoao a ho sebelisoa
Litlhare li fuoe mofuta oa lefu la tsoekere la mofuta oa 2, ha phekolo ea lijo e sa tlise litholoana tse ntle (ho bakuli ba nang le botenya), sena sohle se bontšoa ke litaelo tsa lithethefatsi.
Litekanyetso tsa lithethefatsi li fanoa ke ngaka ka bonngoe ho mokuli ka mong. Phapang ea litekanyetso li bakoa ke ho kenella ha tsoekere maling. Matlapa a formethine a lokela ho nooa nakong ea ha mokuli a qeta ho ja lijo, ntle le ho hlafuna le ho noa metsi a mangata.
Boemong ba pele ba kalafo, tekanyetso e lokela ho ba 0,85g. Nako e le 1 ka letsatsi kapa 0.5g. Makhetlo a 1-2 ka letsatsi. Butle-butle eketsa tekanyetso ho 3g. ka letsatsi.
Bohlokoa! Bakeng sa bakuli ba tsofetseng, tloaelo ea letsatsi le letsatsi ha ea lokela ho feta 1g. Ka lebaka la kotsi e kholo ea lactic acidosis, ka metabolism e matla ea metabolic, lethal dose e lokela ho fokotsoa.
Litlhahiso tse khethehileng bakeng sa tšebeliso
Litaelo: nakong ea kalafo, o hloka ho sebelisa taolo e nepahetseng holim'a ts'ebetso ea renal. Hang kamora likhoeli tse ling le tse ling tse tšeletseng le ka nts'etsopele ea myalgia, ho hlokahala ho tseba hore na lactate e kae ka plasma.
Formetin e ka sebelisoa hammoho le lintho tse tsoang ho sulfonylurea. Tabeng ena, ho hlokahala tlhokomelo e hlokolosi ea khatello ea tsoekere ea mali.
Foromo ka nako ya monotherapy ha e ame bokhoni ba ho sebetsa ka mechini e rarahaneng le ho khanna likoloi. Haeba sethethefatsi se kopantsoe le lithethefatsi tse ling tsa hypoglycemic, tsoelo-pele ea hypoglycemia e ka ba teng, moo ho se nang bokhoni ba ho khanna koloi le ho sebetsa ka mekhoa e rarahaneng e hlokang tlhokomelo e phahameng.
Lintho tse fapaneng tse tla etsahala
Ho tsoa ts'ebetsong ea tšilo ea lijo:
- tatso ea tšepe;
- ho nyekeloa ke pelo, ho hlatsa
- flatulence, lets'ollo;
- tahlehelo ea takatso ea lijo
- bohloko ba ka mpeng.
Ho tsoa lithong tsa hemopoietic, maemong a mang ho ba le anemia ea megalobast ho bonoa.
Mabapi le metabolism:
- e hlokang ho khaotsa ho phekoloa, lactic acidosis ha e fumanehe;
- ka kalafo ea nako e telele, ho hlaha hypovitaminosis B12.
Sistimi ea endocrine ka tekanyetso e sa lekaneng e ka arabela ka hypoglycemia.
Liponahatso tsa ho kula: lekhopho la letlalo.
Ho sebelisana le lithethefatsi tse ling
Phello ea hypoglycemic ea metformin e ka ntlafatsoa ha e sebelisoa ka nako e tšoanang le:
- insulin;
- derivatives ea sulfonylurea;
- oxytetracycline;
- acarbose;
- lithethefatsi tse seng khahlanong le ho ruruha tsa lithethefatsi;
- cyclophosphamide;
- angiotensin e fetolang li-inhibitor tsa enzyme;
- li-inhibitors tsa monoamine oxidase;
- Li-blocker;
- derivatives of clofibrate.
Ho fokotseha ha phello ea hypoglycemic ea metformin ho bonoa ka tšebeliso e tšoanang le:
- loopide le thiazide diuretics;
- lithibela-pelehi tsa molomo
- glucocorticosteroids;
- glucagon;
- epinephrine;
- Lintho tse tsoang ho phenothiazine;
- sympathomimetics;
- nicotinic acid e tsoang ho eona;
- lihormone tsa qoqotho.
Contraindication
Se ke oa nka FORMETINE le:
- ho senyeha ho matla ha renal;
- lefu la tsoekere la ketoacidosis, precoma, coma;
- ho hema le ho nyekeloa ke pelo;
- ho omella;
- kotsi ea methapo ea pelo e mpe haholo;
- ho lemalla joala bo sa foleng le maemo a mang a tlatsetsang kholisong ea lactic acidosis;
- nakong ea bokhachane le pelehi;
- hypersensitivity ho likarolo tsa moriana;
- likotsi le ho kena lipakeng tse tebileng;
- mafu a tšoaetsanoang a matla;
- ho itlopa joala haholo
- lactic acidosis.
Taelo e tsamaeang le ena e re ts'ebeliso ea Formetin ha ea lokela ho tla pele ho lithuto tsa radiology le radioisotope ka kenyelletso ea ntho e fapaneng e nang le iodine ka hare ho matsatsi a mabeli.
Forometine ha e khothalletsoe hore e sebelisoe ke batho ba fetang 60 ba etsang mosebetsi o boima oa 'mele. Haeba molao ona o sa bonoe, bakuli ba joalo ba ka ba le lactic acidosis.
Se boleloang ke thuto ea overdose
Litaelo bakeng sa lithethefatsi Forame ea litlolo li lemosa hore ka ho fetella, ho na le monyetla oa ho nts'etsapele lactic acidosis ka sephetho se bolaeang. Sesosa sa boemo bona e ka ba ho bokellana ha moriana 'meleng ka lebaka la ts'ebetso ea renal e sa sebetseng.
Matšoao a latelang ke matšoao a mantlha a lactic acidosis:
- Ho nyekeloa ke pelo, ho hlatsa.
- Letšollo, bohloko ba ka mpeng.
- Bofokoli, hypothermia.
- Ho tsekela
- Bohloko ba mesifa.
- Reflex bradyarrhythmia.
- Ho theola khatello ea mali.
- Ho sithabela maikutlo le ho holofala
Haeba mokuli a e-na le matšoao a mantlha a lactic acidosis, Foromo e lokela ho qheleloa ka thoko mehatong ea kalafo, mokuli o lokela ho fetisetsoa sepetlele moo ngaka e khonang ho tseba hore na o na le lactate e kae ebe e etsa tlhahlobo e sa utloahaleng.
Mokhoa o sebetsang haholo oa ho tlosa metformin le lactate 'meleng ke hemodialysis, hammoho le kalafo ea matšoao.
Foromo - polokelo, theko
Bophelo ba Shelf ba moriana ke likhoeli tse 24, ka mor'a moo Foromo e ke ke ea sebelisoa. Setlhare ke sa lethathamo la B. E tlameha ho bolokoa sebakeng se lefifi se sa fumanehe ho bana ka mocheso o sa feteng 25 ° C.
Moetsi oa lihlahisoa - Pharmaceard.
Fomu ea tokollo - matlapa a 850 mg. Likotoana tse 60.
Theko - li-ruble tse 177.
Moetsi oa lihlahisoa - Pharmaceard.
Fomu ea tokollo - matlapa a 1gr. Likotoana tse 60.
Theko - 252 rub.
Tse ling tsa li-analogu li theko e boima haholo.
