Boholo ba bakuli ba nang le lefu la tsoekere ba na le mefuta eohle ea maloetse a amanang le eona a mpefatsang boemo ba motho mme a ama lijana tsohle le litho tsohle. E 'ngoe ea maloetse ana ke lefu la tsoekere.
Ntho ea bohlokoa ea lefu lena ke hore methapo eohle ea methapo ea methapo e amehile. Haeba feela likepe tse nyane li senyehile, joale lefu lena le khetholloa e le lefu la tsoekere la tsoekere.
Haeba feela likepe tse kholo tsa sistimi li hlaseloa, lefu lena le bitsoa lefu la tsoekere la macroangiopathy. Empa ana ha se ona feela bothata boo mokuli oa lefu la tsoekere a ka bang le bona. Ka angiopathy, homeostasis e boetse ea ameha.
Matšoao a amanang le lefu la tsoekere la Microangiopathy
Ha u nahana ka matšoao a mantlha a microangiopathy, ho hlahella lintlha tse tharo tse kholo, tse bitsoang Virchow-Sinako triad. Matšoao aa ke eng?
- Mabota a likepe a fetoha.
- Ho ruruha ha mali hoa senyeha.
- Lebelo la mali le fokotseha.
Ka lebaka la ts'ebetso e eketsehileng ea liplatelete le ho eketseha ha methapo ea mali, e ba ntho e mpe haholo. Lisebelisoa tse phetseng hantle li na le lubricant e khethehileng e sa lumelle mali ho khomarela mabota. Sena se tiisa phallo e nepahetseng ea mali.
Lisebelisoa tse ferekaneng ha li khone ho hlahisa monko ona, 'me ho tsamaea butle ha mali hoa etsahala. Lits'oaetso tsena kaofela ha li lebise timetsong ea methapo ea mali feela, empa hape le sebopeho sa microtubuse.
Nakong ea nts'etsopele ea lefu la tsoekere, lefu la mofuta ona le kenyelletsa likepe tse ngata le ho feta. Khafetsa sebaka se anngoeng ke sena ke:
- litho tsa pono;
- myocardium;
- liphio
- tsamaiso ea methapo ea kutlo;
- letlalo le hlakileng.
Liphetho tsa litlolo tsena, joalo ka molao, ke:
- neuropathy;
- lefu la tsoekere;
- cardiopathy
- dermatopathy.
Empa matšoao a pele a hlaha lipheletsong tse tlase, tse bakoang ke ho se sebetse hantle ha methapo ea mali sebakeng sena. Ngoliso ea linyeoe tse joalo e batla e le 65%.
Lingaka tse ling li tloaetse ho pheha khang ea hore microangiopathy ha se lefu le arohaneng, ke hore, ke letšoao la lefu la tsoekere. Ho feta moo, ba lumela hore microangiopathy ke litholoana tsa neuropathy, tse etsahalang pele.
Bo-rasaense ba bang ba bolela hore nerve ischemia e baka neuropathy, 'me' nete ena ha e amanang le tšenyo ea methapo. Ho ea ka khopolo ena, lefu la tsoekere le baka lefu la neuropathy, 'me microangiopathy ha e amane le letho.
Empa ho boetse ho na le khopolo ea boraro, balateli ba eona ba reng ho tlola tšebetso ea methapo ho ka senya methapo ea mali.
Diabetesic Microangiopathy e arotsoe ka mefuta e 'maloa, e bakoang ke tekanyo ea tšenyo lipheletsong tse tlase.
- Ka sekhahla sa tsenyo ea letlalo 'meleng oa motho ha le eo.
- Mokhahlelo oa pele - ho na le mefokolo e nyane letlalong, empa ha e na mekhoa ea ho ruruha mme e fumaneha habobebe.
- Boemong ba bobeli, ho na le liso tsa letlalo tse bonahala tse ka teba hoo li ka lematsang methapo le masapo.
- Karolo ea boraro e tšoantšoa le liso tsa letlalo le lipontšo tsa pele tsa lefu la tishu maotong. Mathata a joalo a ka hlaha hammoho le ts'ebetso ea ts'oaetso, tšoaetso, edema, hyperemia, abscesses le osteomyelitis.
- Boemong ba bone, makhopho a monoana a le mong kapa a 'maloa a qala ho hola.
- Boemo ba bohlano ke leoto kaofela, kapa boholo ba lona bo angoa ke bohlasoa.
Litšobotsi tse ikhethang tsa macroangiopathy
Ntho e ka sehloohong e bakang lefu le phahameng la bakuli ba nang le lefu la tsoekere ke lefu la tsoekere la diabetes. Ke macroangiopathy e atisang ho hlaha ho bakuli ba lefu la tsoekere.
Pele ho tsohle, likepe tse kholo tsa mabalane a tlase lia ameha, ka lebaka leo methapo ea methapo ea kutlo le methapo ea methapo e utloang bohloko.
Macroangiopathy e ka nts'etsapele ts'ebetsong ea ho eketsa sekhahla sa nts'etsopele ea lefu la atherosclerotic. Lefu lena le arotsoe ka mekhahlelo e mengata ea kholo.
- Mokhahlelong oa pele, hoseng mokuli o eketsehile ho tepella, ho fufuleloa ho feteletseng, bofokoli, ho otsela, ho ikutloa o bata le matsoho le ho tsitsipana ha ona. Sena se supa puseletso ho potoloha ho potoloha.
- Mokhahlelong oa bobeli, maoto a motho a qala ho akheha, o thella haholo, bokantle ba lipekere bo qala ho roba. Ka linako tse ling lameness e hlaha sethaleng sena. Ebe ho na le bohloko maotong, ha u tsamaea le ha u phomola. Letlalo le fetoha le boreleli hape le le bosesane. Ho senyeha ho hokahaneng hoa bonoa.
- Mokhahlelo oa ho qetela ke sethoathoa sa lefu la tsoekere la leoto, menoana le leoto le tlase.
Mokhoa oa ho phekola angiopathy
Macro le microangiopathy ho lefu la tsoekere le phekoloa ka mokhoa o tšoanang. Ntho ea pele eo mokuli a lokelang ho e etsa ke ho tlisa ts'ebetso ea metabolic ea mmele maemong a tloaelehileng. Metabolism ea Carbohydrate e lokela ho khutlisoa, hobane hyperglycemia ke lona lebaka le ka sehloohong la nts'etsopele ea atherosulinosis ea methapo ea mali.
Bohlokoa ka mokhoa o lekanang ts'ebetsong ea kalafo ke ho lekola boemo ba metabolism ea lipid. Haeba boemo ba lipoprotein bo nang le matšoao a tlase a letsoalo bo eketsehile ka tšohanyetso, 'me boemo ba li-triglycerides, ka lehlakoreng le leng, bo fokotsehile, sena se bontša hore ke nako ea ho kenyelletsa lithethefatsi tsa hypolipidic kalafong.
Re bua ka li-statins, li-fibrate le li-antioxidants. Macro- le microangiopathy ho lefu la tsoekere mellitus e tšoaroa ka kenyelletso e tlamang ea litlhare tsa kalafo tsa ts'ebetso ea metabolic, mohlala, trimetazidine.
Meriana e joalo e kenya letsoho ts'ebetsong ea oxidation ea tsoekere ho myocardium, e etsahalang ka lebaka la oxidation ea mafura acid. Nakong ea kalafo ea mefuta eohle ea lefu lena, bakuli ba fuoa li-anticoagulants.
Tsena ke lithethefatsi tse thusang ho qhibilihisa mali maling le ho fokolisa tšebetso ea liplatelese ha ho fumanoa hore o na le macroangiopathy.
Ka lebaka la lintho tsena, mali ha a na mali le maemo ha a etsetsoa ho thijoa ha methapo ea mali. Li-anticoagulants li kenyelletsa:
- Acetylsalicylic acid.
- Tiklid.
- Vazaprostan.
- Heparin.
- Dipyridamole.
Bohlokoa! Kaha khatello ea khatello ea mali hangata e ba teng khafetsa ho lefu la tsoekere, ho hlokahala hore o fane ka litlhare tse etsang hore khatello ea mali e tloaelehe. Haeba letšoao lena le tloaelehile, ho ntse ho khothaletsoa ho le lekola kamehla.
Ho tsoekere ea lefu la tsoekere, litekanyetso tse nepahetseng ke 130/85 mm Hg. Mehato e joalo ea taolo e tla thusa ho thibela nts'etsopele ea nephropathy le retinopathy, ho fokotsa haholo kotsi ea ho otloa ke lefu la pelo le ho otla ha pelo.
Har'a lithethefatsi tsena, bahanyetsi ba kananelo ea calcium calcium, li-inhibitors le lithethefatsi tse ling lia khetholoha.
Nakong ea kalafo, ho hlokahala hore ho fetole matšoao a autonomic homeostasis. Bakeng sa sena, lingaka li fana ka lithethefatsi tse eketsang ts'ebetso ea sorbitol dehydrogenase. Ho bohlokoa hape ka ho tšoanang ho etsa mesebetsi e khothalletsang ts'ireletso ea antioxidant.
Ho joalo, ho molemo ho thibela lefu lena qalong. Ho etsa sena, o hloka ho phela bophelo bo nepahetseng mme o shebelle bophelo ba hao bo botle kamehla. Empa haeba ho na le matšoao a lefu la tsoekere, o lokela ho ikopanya le setsi sa bongaka hanghang.
Mekhoa ea sejoale-joale ea kalafo ea lefu la tsoekere le ts'ehetso ea thibelo e ka thusa motho ho qoba litlamorao tse matla tse kang macro- le microangiopathy.
